Antonino Cattaneo

Intranasal administration of nerve growth factor (NGF) rescues recognition memory deficits in AD11 anti-NGF transgenic mice.

Annual fishes of the genus Nothobranchius as a model system for aging research.

Resveratrol prolongs lifespan and retards the onset of age-related markers in a short-lived vertebrate.

Temperature affects longevity and age-related locomotor and cognitive decay in the short-lived fish Nothobranchius furzeri.

Large differences in aging phenotype between strains of the short-lived annual fish Nothobranchius furzeri.

In the adult hippocampus, chronic nerve growth factor deprivation shifts GABAergic signaling from the hyperpolarizing to the depolarizing direction.

Dissecting the involvement of tropomyosin-related kinase A and p75 neurotrophin receptor signaling in NGF deficit-induced neurodegeneration.

Transgenic mice with chronic NGF deprivation and Alzheimer's disease-like pathology display hippocampal region-specific impairments in short- and long-term plasticities.

Taking pain out of NGF: a "painless" NGF mutant, linked to hereditary sensory autonomic neuropathy type V, with full neurotrophic activity.

Intranasal delivery of therapeutic proteins for neurological diseases.

NGF and proNGF regulate functionally distinct mRNAs in PC12 cells: an early gene expression profiling.

Conformational plasticity of proNGF.

Single particle tracking of acyl carrier protein (ACP)-tagged TrkA receptors in PC12nnr5 cells.

Single cycle structure-based humanization of an anti-nerve growth factor therapeutic antibody.

Pathogen free conditions slow the onset of neurodegeneration in a mouse model of nerve growth factor deprivation.

RACK1 is a ribosome scaffold protein for β-actin mRNA/ZBP1 complex.

Intranasal "painless" human Nerve Growth Factor [corrected] slows amyloid neurodegeneration and prevents memory deficits in App X PS1 mice.

IGF-1 restores visual cortex plasticity in adult life by reducing local GABA levels.

SorLA deficiency dissects amyloid pathology from tau and cholinergic neurodegeneration in a mouse model of Alzheimer's disease.

Dissecting the role of sortilin receptor signaling in neurodegeneration induced by NGF deprivation.

Nerve growth factor scales endocannabinoid signaling by regulating monoacylglycerol lipase turnover in developing cholinergic neurons.

Immunosympathectomy as the first phenotypic knockout with antibodies.

Ligand signature in the membrane dynamics of single TrkA receptor molecules.

Characterization of mitochondrial dysfunction in the 7PA2 cell model of Alzheimer's disease.

proNGF/NGF mixtures induce gene expression changes in PC12 cells that neither singly produces.

Amyloid plaque-independent deficit of early postnatal visual cortical plasticity in the 5XFAD transgenic model of Alzheimer's disease.

Conformational targeting of intracellular Aβ oligomers demonstrates their pathological oligomerization inside the endoplasmic reticulum.

Site-specific labeling of neurotrophins and their receptors via short and versatile peptide tags.

A comparative analysis of the structural, functional and biological differences between Mouse and Human Nerve Growth Factor.

Ligand-induced dynamics of neurotrophin receptors investigated by single-molecule imaging approaches.

The conundrum of the high-affinity NGF binding site formation unveiled?

Time dynamics of protein complexes in the AD11 transgenic mouse model for Alzheimer's disease like pathology.

New strategies to address the pharmacodynamics and pharmacokinetics of tumor necrosis factor (TNF) inhibitors: A systematic analysis.

Functional Characterization of Human ProNGF and NGF Mutants: Identification of NGF P61SR100E as a "Painless" Lead Investigational Candidate for Therapeutic Applications.

TIMP3 interplays with apelin to regulate cardiovascular metabolism in hypercholesterolemic mice.

Precursor and mature NGF live tracking: one versus many at a time in the axons.

The chemokine CXCL12 mediates the anti-amyloidogenic action of painless human nerve growth factor.

Post-translational selective intracellular silencing of acetylated proteins with de novo selected intrabodies.

Increased cytoplasmic TDP-43 reduces global protein synthesis by interacting with RACK1 on polyribosomes.

Nerve growth factor derivative NGF61/100 promotes outgrowth of primary sensory neurons with reduced signs of nociceptive sensitization.

An Optimized Procedure for the Site-Directed Labeling of NGF and proNGF for Imaging Purposes.

ProNGF Drives Localized and Cell Selective Parvalbumin Interneuron and Perineuronal Net Depletion in the Dentate Gyrus of Transgenic Mice.

Assessment of antibody library diversity through next generation sequencing and technical error compensation.

Activity-dependent expression of Channelrhodopsin at neuronal synapses.

Site-Specific Direct Labeling of Neurotrophins and Their Receptors: From Biochemistry to Advanced Imaging Applications.

Toxic properties of microsome-associated alpha-synuclein species in mouse primary neurons.

NGF steers microglia toward a neuroprotective phenotype.

The retina as a window to early dysfunctions of Alzheimer's disease following studies with a 5xFAD mouse model.

Arc 3' UTR Splicing Leads to Dual and Antagonistic Effects in Fine-Tuning Arc Expression Upon BDNF Signaling.

Painless Nerve Growth Factor: A TrkA biased agonist mediating a broad neuroprotection via its actions on microglia cells.

The Structure of the Pro-domain of Mouse proNGF in Contact with the NGF Domain.

Corrigendum: Increased cytoplasmic TDP-43 reduces global protein synthesis by interacting with RACK1 on polyribosomes.

Targeting the Post-translational Proteome with Intrabodies.

Cholinergic striatal neurons are increased in HSAN V homozygous mice despite reduced NGF bioavailability.

A triheptanoin-supplemented diet rescues hippocampal hyperexcitability and seizure susceptibility in FoxG1 mice.

A continuous model of physiological prion aggregation suggests a role for Orb2 in gating long-term synaptic information.

Tau Modulates VGluT1 Expression.

Constipation, deficit in colon contractions and alpha-synuclein inclusions within the colon precede motor abnormalities and neurodegeneration in the central nervous system in a mouse model of alpha-synucleinopathy.

ProNGF Is a Cell-Type-Specific Mitogen for Adult Hippocampal and for Induced Neural Stem Cells.

Tuning GABAergic Inhibition: Gephyrin Molecular Organization and Functions.

Cortical Seizures in Mice are Accompanied by Akt/S6 Overactivation, Excitation/Inhibition Imbalance and Impaired Synaptic Transmission.

Identification of an ERK Inhibitor as a Therapeutic Drug Against Tau Aggregation in a New Cell-Based Assay.

Fast-diffusing p75 monomers support apoptosis and growth cone collapse by neurotrophin ligands.

Impaired adult neurogenesis is an early event in Alzheimer's disease neurodegeneration, mediated by intracellular Aβ oligomers.

Protein Structural Information and Evolutionary Landscape by In Vitro Evolution.

The NGF Mutation Specifically Impairs Nociception without Affecting Cognitive Performance in a Mouse Model of Hereditary Sensory and Autonomic Neuropathy Type V.