Muhammad Tehseen

Dynamic structure mediates halophilic adaptation of a DNA polymerase from the deep-sea brines of the Red Sea.

Resolution of the Holliday junction recombination intermediate by human GEN1 at the single-molecule level.

Initial state of DNA-Dye complex sets the stage for protein induced fluorescence modulation.

Proliferating cell nuclear antigen-agarose column: A tag-free and tag-dependent tool for protein purification affinity chromatography.

Functional binding of E-selectin to its ligands is enhanced by structural features beyond its lectin domain.

Fusion of the Cas9 endonuclease and the VirD2 relaxase facilitates homology-directed repair for precise genome engineering in rice.

Structure of the processive human Pol δ holoenzyme.

Two chromatographic schemes for protein purification involving the biotin/avidin interaction under native conditions.

iSCAN: An RT-LAMP-coupled CRISPR-Cas12 module for rapid, sensitive detection of SARS-CoV-2.

Using Eukaryotic Expression Systems to Generate Human α1,3-Fucosyltransferases That Effectively Create Selectin-Binding Glycans on Stem Cells.

Quick and Easy Assembly of a One-Step qRT-PCR Kit for COVID-19 Diagnostics Using In-House Enzymes.

Vigilant: An Engineered VirD2-Cas9 Complex for Lateral Flow Assay-Based Detection of SARS-CoV2.

Implementing fluorescence enhancement, quenching, and FRET for investigating flap endonuclease 1 enzymatic reaction at the single-molecule level.

Cryo-EM structure of human Pol κ bound to DNA and mono-ubiquitylated PCNA.

Bio-SCAN: A CRISPR/dCas9-Based Lateral Flow Assay for Rapid, Specific, and Sensitive Detection of SARS-CoV-2.

Wiskott-Aldrich syndrome protein forms nuclear condensates and regulates alternative splicing.

Author Correction: Wiskott-Aldrich syndrome protein forms nuclear condensates and regulates alternative splicing.

Mechanistic investigation of human maturation of Okazaki fragments reveals slow kinetics.

A scanning-to-incision switch in TFIIH-XPG induced by DNA damage licenses nucleotide excision repair.

Mechanism of human Lig1 regulation by PCNA in Okazaki fragment sealing.

Author Correction: Mechanism of human Lig1 regulation by PCNA in Okazaki fragment sealing.

Interaction of human HelQ with DNA polymerase delta halts DNA synthesis and stimulates DNA single-strand annealing.

Efficient in planta production of amidated antimicrobial peptides that are active against drug-resistant ESKAPE pathogens.