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Cardiovascular Research Center
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Small molecule-mediated directed differentiation of human embryonic stem cells toward ventricular cardiomyocytes.
Stem cells translational medicine Jan, 2014 | Pubmed ID: 24324277
Considerations for pre-clinical models and clinical trials of pluripotent stem cell-derived cardiomyocytes.
Stem cell research & therapy Jan, 2014 | Pubmed ID: 24405778
Correction of human phospholamban R14del mutation associated with cardiomyopathy using targeted nucleases and combination therapy.
Nature communications , 2015 | Pubmed ID: 25923014
Genomic correction of familial cardiomyopathy in human engineered cardiac tissues.
European heart journal Nov, 2016 | Pubmed ID: 27450564
Gene Transfer in Cardiomyocytes Derived from ES and iPS Cells.
Methods in molecular biology (Clifton, N.J.) , 2017 | Pubmed ID: 27910049
Modeling susceptibility to drug-induced long QT with a panel of subject-specific induced pluripotent stem cells.
eLife 01, 2017 | Pubmed ID: 28134617
Functional Human Beige Adipocytes From Induced Pluripotent Stem Cells.
Diabetes 06, 2017 | Pubmed ID: 28270520
Exosomal microRNA-21-5p Mediates Mesenchymal Stem Cell Paracrine Effects on Human Cardiac Tissue Contractility.
Circulation research 03, 2018 | Pubmed ID: 29449318
Functional and transcriptomic insights into pathogenesis of R9C phospholamban mutation using human induced pluripotent stem cell-derived cardiomyocytes.
Journal of molecular and cellular cardiology Jun, 2018 | Pubmed ID: 29752948
Cardiac Tissue Engineering Models of Inherited and Acquired Cardiomyopathies.
Methods in molecular biology (Clifton, N.J.) , 2018 | Pubmed ID: 29987817
Adult human cardiac stem cell supplementation effectively increases contractile function and maturation in human engineered cardiac tissues.
Stem cell research & therapy Dec, 2019 | Pubmed ID: 31801634
Impaired Right Ventricular Calcium Cycling Is an Early Risk Factor in R14del-Phospholamban Arrhythmias.
Journal of personalized medicine Jun, 2021 | Pubmed ID: 34204946
Generation of human induced pluripotent stem cell (iPSC) lines derived from five patients carrying the pathogenic phospholamban-R14del (PLN-R14del) variant and three non-carrier family members.
Stem cell research Apr, 2022 | Pubmed ID: 35247838
Isoform changes of action potential regulators in the ventricles of arrhythmogenic phospholamban-R14del humanized mouse hearts.
Metabolism: clinical and experimental Jan, 2023 | Pubmed ID: 36375644
Myofilament Alterations Associated with Human R14del-Phospholamban Cardiomyopathy.
International journal of molecular sciences Jan, 2023 | Pubmed ID: 36768995
Icahn School of Medicine at Mount Sinai
University Medical Center Utrecht
Jae Gyun Oh1,
Jaydev Dave1,
Changwon Kho1,
Francesca Stillitano1
1Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai
Renee G. C. Maas1,
Tess Beekink*,1,
Nino Chirico*,1,
Christian J. B. Snijders Blok1,
Inge Dokter1,
Vasco Sampaio-Pinto1,
Alain van Mil1,
Pieter A. Doevendans1,
Jan W. Buikema2,
Joost P. G. Sluijter*,1,
Francesca Stillitano*,1
1Utrecht Regenerative Medicine Center, Circulatory Health Laboratory, University Utrecht, Department of Cardiology, University Medical Center Utrecht,
2Amsterdam Cardiovascular Sciences, Department of Physiology, Amsterdam University Medical Center
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