Research Center for Pharmacology & Toxicology,
Institute of Medicinal Plant Development (IMPLAD),
Research Center for Pharmacology & Toxicology, Institute of Medicinal Plant Development (IMPLAD)
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Immune responses in mice to arecoline mediated by lymphocyte muscarinic acetylcholine receptor.
Cell biology international Dec, 2006 | Pubmed ID: 17084646
Comparison of ginsenosides Rg1 and Rb1 for their effects on improving scopolamine-induced learning and memory impairment in mice.
Phytotherapy research : PTR Dec, 2010 | Pubmed ID: 20564503
Cognitive-enhancing effects of polygalasaponin hydrolysate in aβ(25-35)-induced amnesic mice.
Evidence-based complementary and alternative medicine : eCAM , 2011 | Pubmed ID: 21423642
Neuroprotective effects of forsythiaside on learning and memory deficits in senescence-accelerated mouse prone (SAMP8) mice.
Pharmacology, biochemistry, and behavior Apr, 2013 | Pubmed ID: 23290932
Different pharmacokinetics of the two structurally similar dammarane sapogenins, protopanaxatriol and protopanaxadiol, in rats.
Fitoterapia Apr, 2013 | Pubmed ID: 23391424
Antidepressant-like effects and memory enhancement of a herbal formula in mice exposed to chronic mild stress.
Neuroscience bulletin Dec, 2013 | Pubmed ID: 24132797
Identification and characterization of potent CYP2D6 inhibitors in lotus leaves.
Journal of ethnopharmacology Apr, 2014 | Pubmed ID: 24561383
Antidepressant-like effects and mechanism of action of SYG in depression model in rats.
Neuro endocrinology letters , 2014 | Pubmed ID: 24878971
Cajaninstilbene acid protects corticosterone-induced injury in PC12 cells by inhibiting oxidative and endoplasmic reticulum stress-mediated apoptosis.
Neurochemistry international Dec, 2014 | Pubmed ID: 25193317
Tenuifolin, a secondary saponin from hydrolysates of polygalasaponins, counteracts the neurotoxicity induced by Aβ25-35 peptides in vitro and in vivo.
Pharmacology, biochemistry, and behavior Jan, 2015 | Pubmed ID: 25444865
Tong Luo Jiu Nao ameliorates Aβ1-40-induced cognitive impairment on adaptive behavior learning by modulating ERK/CaMKII/CREB signaling in the hippocampus.
BMC complementary and alternative medicine Mar, 2015 | Pubmed ID: 25888276
An LC-MS/MS method for simultaneous determination of three Polygala saponin hydrolysates in rat plasma and its application to a pharmacokinetic study.
Journal of ethnopharmacology Jul, 2015 | Pubmed ID: 25922266
Lotus Leaf Alkaloid Extract Displays Sedative-Hypnotic and Anxiolytic Effects through GABAA Receptor.
Journal of agricultural and food chemistry Oct, 2015 | Pubmed ID: 26448283
Antioxidant and Anti-Fatigue Constituents of Okra.
Nutrients Oct, 2015 | Pubmed ID: 26516905
Metabolism profiles of nuciferine in rats using ultrafast liquid chromatography with tandem mass spectrometry.
Biomedical chromatography : BMC Aug, 2016 | Pubmed ID: 26682724
Chronical sleep interruption-induced cognitive decline assessed by a metabolomics method.
Behavioural brain research Apr, 2016 | Pubmed ID: 26747207
LC/MS-based metabolomics strategy to assess the amelioration effects of ginseng total saponins on memory deficiency induced by simulated microgravity.
Journal of pharmaceutical and biomedical analysis Jun, 2016 | Pubmed ID: 27100700
The memory enhancement effect of Kai Xin San on cognitive deficit induced by simulated weightlessness in rats.
Journal of ethnopharmacology Jul, 2016 | Pubmed ID: 27103112
Cognitive-enhancing effects of hydrolysate of polygalasaponin in SAMP8 mice.
Journal of Zhejiang University. Science. B Jul, 2016 | Pubmed ID: 27381727
Protective effect of lavender oil on scopolamine induced cognitive deficits in mice and HO induced cytotoxicity in PC12 cells.
Journal of ethnopharmacology Dec, 2016 | Pubmed ID: 27558947
Antidepressant-like effects and cognitive enhancement of the total phenols extract of Hemerocallis citrina Baroni in chronic unpredictable mild stress rats and its related mechanism.
Journal of ethnopharmacology Dec, 2016 | Pubmed ID: 27623554
Kai Xin San aqueous extract improves Aβ1-40-induced cognitive deficits on adaptive behavior learning by enhancing memory-related molecules expression in the hippocampus.
Journal of ethnopharmacology Apr, 2017 | Pubmed ID: 27751826
Effects of the chronic restraint stress induced depression on reward-related learning in rats.
Behavioural brain research 03, 2017 | Pubmed ID: 28065844
Effects of phenolic constituents of daylily flowers on corticosterone- and glutamate-treated PC12 cells.
BMC complementary and alternative medicine Jan, 2017 | Pubmed ID: 28109297
Plasma and brain pharmacokinetics of ganoderic acid A in rats determined by a developed UFLC-MS/MS method.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences May, 2017 | Pubmed ID: 28346885
[Antidepressant effects of the extract of Dendrobium nobile Lindl on chronic unpredictable mild stress-induced depressive mice].
Sheng li xue bao : [Acta physiologica Sinica] Apr, 2017 | Pubmed ID: 28435974
Pharmacokinetics of Cajaninstilbene Acid and Its Main Glucuronide Metabolite in Rats.
Journal of agricultural and food chemistry May, 2017 | Pubmed ID: 28485147
20(S)-protopanaxadiol (PPD) alleviates scopolamine-induced memory impairment via regulation of cholinergic and antioxidant systems, and expression of Egr-1, c-Fos and c-Jun in mice.
Chemico-biological interactions Jan, 2018 | Pubmed ID: 29133030
Agarwood Essential Oil Displays Sedative-Hypnotic Effects through the GABAergic System.
Molecules (Basel, Switzerland) Dec, 2017 | Pubmed ID: 29232839
Antidepressant effects of dammarane sapogenins in chronic unpredictable mild stress-induced depressive mice.
Phytotherapy research : PTR Jun, 2018 | Pubmed ID: 29468732
Rapid Determination of Active Compounds and Antioxidant Activity of Okra Seeds Using Fourier Transform Near Infrared (FT-NIR) Spectroscopy.
Molecules (Basel, Switzerland) Mar, 2018 | Pubmed ID: 29498632
Effect of Ginkgo biloba extract-761 on motor functions in permanent middle cerebral artery occlusion rats.
Phytomedicine : international journal of phytotherapy and phytopharmacology Sep, 2018 | Pubmed ID: 30195885
Resolving neuroinflammation, the therapeutic potential of the anti-malaria drug family of artemisinin.
Pharmacological research 10, 2018 | Pubmed ID: 30196102
Agarwood Essential Oil Ameliorates Restrain Stress-Induced Anxiety and Depression by Inhibiting HPA Axis Hyperactivity.
International journal of molecular sciences Nov, 2018 | Pubmed ID: 30400578
Liquid chromatography-mass spectrometry-based urinary metabolomics study on a rat model of simulated microgravity-induced depression.
Journal of pharmaceutical and biomedical analysis Feb, 2019 | Pubmed ID: 30502550
Alginate Hydrogel Modified with a Ligand Interacting with α3β1 Integrin Receptor Promotes the Differentiation of 3D Neural Spheroids toward Oligodendrocytes in Vitro.
ACS applied materials & interfaces Feb, 2019 | Pubmed ID: 30645095
LC-MS/MS-based quantification of tryptophan metabolites and neurotransmitters in the serum and brain of mice.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences Apr, 2019 | Pubmed ID: 30836315
Postweaning Isolation Rearing Alters the Adult Social, Sexual Preference and Mating Behaviors of Male CD-1 Mice.
Frontiers in behavioral neuroscience , 2019 | Pubmed ID: 30873013
Time-dependent impairments in learning and memory in Streptozotocin-induced hyperglycemic rats.
Metabolic brain disease 10, 2019 | Pubmed ID: 31286327
Antidepressant-like effects of 20(S)-protopanaxadiol in a mouse model of chronic social defeat stress and the related mechanisms.
Phytotherapy research : PTR Oct, 2019 | Pubmed ID: 31353678
Urinary metabolic disturbance in the olfactory bulbectomized rats and the modulatory effects of fluoxetine.
Life sciences Oct, 2019 | Pubmed ID: 31415771
Dammarane sapogenins alleviates depression-like behaviours induced by chronic social defeat stress in mice through the promotion of the BDNF signalling pathway and neurogenesis in the hippocampus.
Brain research bulletin Nov, 2019 | Pubmed ID: 31542427
Cajaninstilbene Acid Ameliorates Cognitive Impairment Induced by Intrahippocampal Injection of Amyloid-β Oligomers.
Frontiers in pharmacology , 2019 | Pubmed ID: 31680939
Antidepressant-like effects of cajaninstilbene acid and its related mechanisms in mice.
Fitoterapia Mar, 2020 | Pubmed ID: 31837410
1Department of Psychiatry, The Second Xiangya Hospital, Central South University, National Clinical Research Center for Mental Disorders and National Technology Institute on Mental Disorders, Hunan Key Laboratory of Psychiatry and Mental Health,
2Research Center for Pharmacology & Toxicology, Institute of Medicinal Plant Development (IMPLAD), Chinese Academy of Medical Sciences and Peking Union Medical College,
3Department of Social Medicine and Health Management, Xiangya School of Public Health, Central South University