In 1980 Giovanni Paganelli received his degree in Medicine and Surgery at University of Bologna, Italy. In 1997 he optimized the lymphoscintigraphic technique for the detection of the sentinel node in breast cancer and conceived Radio-guided Occult Lesion Localization (ROLL), a new non-palpable lesions localization system. His main field of interest is the in vivo application of the avidin-biotin system and radiolabelled peptides. He is engaged in investigating new radiopharmaceuticals for targeted molecular radionuclide therapy in oncology and radiolabeled peptides in neuroendocrine tumors as well as new approach in their application for diagnostic and therapeutical purposes. Among other honors, Prof. Paganelli is the 1998 recipient of the Marie Curie Award from the European Association of Nuclear Medicine. He is the owner of several International Patents and has been an invited lecturer at several Italian and International Universities. From February 2001 to December 2003, he served as an Expert of the Consiglio Superiore di Sanità (Italian Health Commission). His Official H index it’s equal to 67.0 and he is Author/co-author of more than 360 articles in leading international peer-reviewed journals as well as he is member of the editorial board of several scientific Journals (e.g. EJNMMI, QJNMMI, Cancer Bioth & Rad, Clin.Trans.Imag. ).