Ricerca
Didattica
Soluzioni
Accedi
IT
EN - English
CN - 中文
DE - Deutsch
ES - Español
KR - 한국어
IT - Italiano
FR - Français
PT - Português
TR - Turkish
JA - Japanese
NCI RAS Initiative,
Cancer Research Technology Program,
NCI RAS Initiative, Cancer Research Technology Program
Andrew G. Stephen has not added Biography.
If you are Andrew G. Stephen and would like to personalize this page please email our Author Liaison for assistance.
Dragging ras back in the ring.
Cancer cell Mar, 2014 | Pubmed ID: 24651010
Biochemical assays for the discovery of TDP1 inhibitors.
Molecular cancer therapeutics Aug, 2014 | Pubmed ID: 25024006
Farnesylated and methylated KRAS4b: high yield production of protein suitable for biophysical studies of prenylated protein-lipid interactions.
Scientific reports Nov, 2015 | Pubmed ID: 26522388
Structural basis of recognition of farnesylated and methylated KRAS4b by PDEδ.
Proceedings of the National Academy of Sciences of the United States of America 11, 2016 | Pubmed ID: 27791178
Inhibition of Ras/Raf/MEK/ERK Pathway Signaling by a Stress-Induced Phospho-Regulatory Circuit.
Molecular cell 12, 2016 | Pubmed ID: 27889448
K-Ras4B Remains Monomeric on Membranes over a Wide Range of Surface Densities and Lipid Compositions.
Biophysical journal 01, 2018 | Pubmed ID: 29320680
New weapons to penetrate the armor: Novel reagents and assays developed at the NCI RAS Initiative to enable discovery of RAS therapeutics.
Seminars in cancer biology 02, 2019 | Pubmed ID: 29432816
Molecular recognition of RAS/RAF complex at the membrane: Role of RAF cysteine-rich domain.
Scientific reports 05, 2018 | Pubmed ID: 29855542
The bacterial Ras/Rap1 site-specific endopeptidase RRSP cleaves Ras through an atypical mechanism to disrupt Ras-ERK signaling.
Science signaling 10, 2018 | Pubmed ID: 30279169
Quantitative biophysical analysis defines key components modulating recruitment of the GTPase KRAS to the plasma membrane.
The Journal of biological chemistry 02, 2019 | Pubmed ID: 30559287
KRAS Prenylation Is Required for Bivalent Binding with Calmodulin in a Nucleotide-Independent Manner.
Biophysical journal 03, 2019 | Pubmed ID: 30846362
Structures of N-terminally processed KRAS provide insight into the role of N-acetylation.
Scientific reports Jul, 2019 | Pubmed ID: 31324887
Organization of Farnesylated, Carboxymethylated KRAS4B on Membranes.
Journal of molecular biology Sep, 2019 | Pubmed ID: 31330153
PIP2 Influences the Conformational Dynamics of Membrane-Bound KRAS4b.
Biochemistry Aug, 2019 | Pubmed ID: 31339036
Second harmonic generation detection of Ras conformational changes and discovery of a small molecule binder.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2019 | Pubmed ID: 31399543
Frederick National Laboratory for Cancer Research
Constance Agamasu1,
Peter Frank1,
Shelley Perkins1,
Timothy Waybright1,
Simon Messing1,
William Gillette1,
Andrew G. Stephen1
1NCI RAS Initiative, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research
Riservatezza
Condizioni di utilizzo
Politiche
Contattaci
SUGGERISCI JOVE ALLA BIBLIOTECA
Newsletter di JoVE
JoVE Journal
Raccolta di metodi
JoVE Encyclopedia of Experiments
Archivio
JoVE Core
JoVE Business
JoVE Science Education
JoVE Lab Manual
Sportello unico per docenti
Autori
Personale delle biblioteche
Accesso
CHI SIAMO
Copyright © 2024 MyJoVE Corporation. Tutti i diritti riservati