Gerhard Leinenga

What Renders TAU Toxic.

Scanning ultrasound removes amyloid-β and restores memory in an Alzheimer's disease mouse model.

Ultrasound treatment of neurological diseases--current and emerging applications.

Scanning Ultrasound (SUS) Causes No Changes to Neuronal Excitability and Prevents Age-Related Reductions in Hippocampal CA1 Dendritic Structure in Wild-Type Mice.

Combined effects of scanning ultrasound and a tau-specific single chain antibody in a tau transgenic mouse model.

Establishing sheep as an experimental species to validate ultrasound-mediated blood-brain barrier opening for potential therapeutic interventions.

Modeling ultrasound propagation through material of increasing geometrical complexity.

Ultrasound-mediated blood-brain barrier opening enhances delivery of therapeutically relevant formats of a tau-specific antibody.

Repeated ultrasound treatment of tau transgenic mice clears neuronal tau by autophagy and improves behavioral functions.

Scanning ultrasound in the absence of blood-brain barrier opening is not sufficient to clear β-amyloid plaques in the APP23 mouse model of Alzheimer's disease.