Department of Microbiology and Immunology,
Yong Loo Lin School of Medicine,
NUHS Infectious Diseases Translational Research Program,
Department of Microbiology and Immunology, Yong Loo Lin School of Medicine,
NUHS Infectious Diseases Translational Research Program, Yong Loo Lin School of Medicine
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The human DENN gene: genomic organization, alternative splicing, and localization to chromosome 11p11.21-p11.22.
Genome Aug, 1998 | Pubmed ID: 9796103
Identification of multiple genital HPV types and sequence variants by consensus and nested type-specific PCR coupled with cycle sequencing.
Pathology Aug, 2000 | Pubmed ID: 10968397
Diagnosis of nipah virus encephalitis by electron microscopy of cerebrospinal fluid.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology Dec, 2000 | Pubmed ID: 11090749
Phylogenetic relationships of the seven coat protein subunits of the coatomer complex, and comparative sequence analysis of murine xenin and proxenin.
Biochemical genetics Jun, 2001 | Pubmed ID: 11530856
Complete sequence analyses of enterovirus 71 strains from fatal and non-fatal cases of the hand, foot and mouth disease outbreak in Singapore (2000).
Microbiology and immunology , 2002 | Pubmed ID: 12516778
Measurement of serum leptin concentrations in university undergraduates by competitive ELISA reveals correlations with body mass index and sex.
Advances in physiology education Dec, 2003 | Pubmed ID: 12760843
Differential expression of metallothionein 1 and 2 isoforms in breast cancer lines with different invasive potential: identification of a novel nonsilent metallothionein-1H mutant variant.
The American journal of pathology Nov, 2003 | Pubmed ID: 14578200
Differential expression of metallothionein isoforms in nasopharyngeal cancer and inhibition of cell growth by antisense down-regulation of metallothionein-2A.
Oncology reports Jan, 2005 | Pubmed ID: 15583813
Recombinant non-structural 1 (NS1) protein of dengue-2 virus interacts with human STAT3beta protein.
Virus research Sep, 2005 | Pubmed ID: 15878791
RNA interference against enterovirus 71 infection.
Virology Oct, 2005 | Pubmed ID: 16083932
Specific detection of enterovirus 71 directly from clinical specimens using real-time RT-PCR hybridization probe assay.
Molecular and cellular probes Apr, 2006 | Pubmed ID: 16460910
Identification of neutralizing linear epitopes from the VP1 capsid protein of Enterovirus 71 using synthetic peptides.
Virus research Apr, 2007 | Pubmed ID: 17222936
Enhanced potency and efficacy of 29-mer shRNAs in inhibition of Enterovirus 71.
Antiviral research Apr, 2007 | Pubmed ID: 17316836
Inhibition of enterovirus 71 in virus-infected mice by RNA interference.
Molecular therapy : the journal of the American Society of Gene Therapy Nov, 2007 | Pubmed ID: 17712333
Passive protection against lethal enterovirus 71 infection in newborn mice by neutralizing antibodies elicited by a synthetic peptide.
Microbes and infection Sep, 2007 | Pubmed ID: 17890123
Rapid detection of enterovirus 71 by real-time TaqMan RT-PCR.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology Jun, 2008 | Pubmed ID: 18304867
Development of multiplex real-time hybridization probe reverse transcriptase polymerase chain reaction for specific detection and differentiation of Enterovirus 71 and Coxsackievirus A16.
Diagnostic microbiology and infectious disease Jul, 2008 | Pubmed ID: 18394844
MCP-1 antibody treatment enhances damage and impedes repair of the alveolar epithelium in influenza pneumonitis.
American journal of respiratory cell and molecular biology Jun, 2010 | Pubmed ID: 19617401
Characterization of a monoclonal antibody against the 3D polymerase of enterovirus 71 and its use for the detection of human enterovirus A infection.
Journal of virological methods Mar, 2012 | Pubmed ID: 22226793
Characterization and specificity of the linear epitope of the enterovirus 71 VP2 protein.
Virology journal Feb, 2012 | Pubmed ID: 22361222
Neutrophils infected with highly virulent influenza H3N2 virus exhibit augmented early cell death and rapid induction of type I interferon signaling pathways.
Genomics Nov, 2012 | Pubmed ID: 23195410
A novel universal neutralizing monoclonal antibody against enterovirus 71 that targets the highly conserved "knob" region of VP3 protein.
PLoS neglected tropical diseases , 2014 | Pubmed ID: 24875055
Combination therapy with hepatocyte growth factor and oseltamivir confers enhanced protection against influenza viral pneumonia.
Current molecular medicine , 2014 | Pubmed ID: 24894172
Angiopoietin-like 4 Increases Pulmonary Tissue Leakiness and Damage during Influenza Pneumonia.
Cell reports Feb, 2015 | Pubmed ID: 25660016
A monoclonal antibody binds to threonine 49 in the non-structural 1 protein of influenza A virus and interferes with its ability to modulate viral replication.
Antiviral research Apr, 2015 | Pubmed ID: 25666762
Impedimetric cell-based biosensor for real-time monitoring of cytopathic effects induced by dengue viruses.
Biosensors & bioelectronics Aug, 2015 | Pubmed ID: 25794961
Seroepidemiology of Coxsackievirus A6, Coxsackievirus A16, and Enterovirus 71 Infections among Children and Adolescents in Singapore, 2008-2010.
PloS one , 2015 | Pubmed ID: 26011735
Evaluation of antiviral activities of Houttuynia cordata Thunb. extract, quercetin, quercetrin and cinanserin on murine coronavirus and dengue virus infection.
Asian Pacific journal of tropical medicine Jan, 2016 | Pubmed ID: 26851778
Capsules of virulent pneumococcal serotypes enhance formation of neutrophil extracellular traps during in vivo pathogenesis of pneumonia.
Oncotarget Apr, 2016 | Pubmed ID: 27034012
Biochemical and structural characterization of the interface mediating interaction between the influenza A virus non-structural protein-1 and a monoclonal antibody.
Scientific reports 09, 2016 | Pubmed ID: 27633136
Human genome-wide RNAi screen reveals host factors required for enterovirus 71 replication.
Nature communications 10, 2016 | Pubmed ID: 27748395
Effective in vivo therapeutic IgG antibody against VP3 of enterovirus 71 with receptor-competing activity.
Scientific reports 04, 2017 | Pubmed ID: 28422137
Epidemiology and Relative Severity of Influenza Subtypes in Singapore in the Post-Pandemic Period from 2009 to 2010.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America Nov, 2017 | Pubmed ID: 29028950
Antibody Treatment against Angiopoietin-Like 4 Reduces Pulmonary Edema and Injury in Secondary Pneumococcal Pneumonia.
mBio 06, 2019 | Pubmed ID: 31164474
Insights into Early Recovery from Influenza Pneumonia by Spatial and Temporal Quantification of Putative Lung Regenerating Cells and by Lung Proteomics.
Cells 08, 2019 | Pubmed ID: 31455003
RNA Sequencing of H3N2 Influenza Virus-Infected Human Nasal Epithelial Cells from Multiple Subjects Reveals Molecular Pathways Associated with Tissue Injury and Complications.
Cells 08, 2019 | Pubmed ID: 31461941
Molecular insights into evolution, mutations and receptor-binding specificity of influenza A and B viruses from outpatients and hospitalized patients in Singapore.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases Jan, 2020 | Pubmed ID: 31669593
Monoclonal antibodies for the S2 subunit of spike of SARS-CoV-1 cross-react with the newly-emerged SARS-CoV-2.
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 07, 2020 | Pubmed ID: 32700671
Enteroviral 3C protease activates the human NLRP1 inflammasome in airway epithelia.
Science (New York, N.Y.) 12, 2020 | Pubmed ID: 33093214
Zhe Zhang Ryan Lew*,1,
Jing Liu*,1,
Hsiao Hui Ong1,
Vivian Jiayi Tan2,
Annika Luukkainen3,
Yew Kwang Ong1,4,
Mark Thong1,4,
Kia Joo Puan5,
Vincent Tak Kwong Chow2,6,
Kai Sen Tan1,2,6,
De Yun Wang1,6
1Department of Otolaryngology, Yong Loo Lin School of Medicine, National University of Singapore,
2Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore,
3Haartman Institute, Medicum, University of Helsinki,
4Department of Otolaryngology, Head and Neck Surgery, National University Hospital, National University Health System,
5Agency for Science, Technology and Research (A*STAR), Singapore Immunology Network (SIgN),
6NUHS Infectious Diseases Translational Research Program, Yong Loo Lin School of Medicine, National University of Singapore