Marion MacFarlane

c-Myc protein synthesis is initiated from the internal ribosome entry segment during apoptosis.

Mechanisms of resistance to TRAIL-induced apoptosis in primary B cell chronic lymphocytic leukaemia.

TRAIL-induced signalling and apoptosis.

Caspase activation inhibits proteasome function during apoptosis.

Apoptosis and disease: a life or death decision.

TRAIL signals to apoptosis in chronic lymphocytic leukaemia cells primarily through TRAIL-R1 whereas cross-linked agonistic TRAIL-R2 antibodies facilitate signalling via TRAIL-R2.

Recombinant TRAIL and TRAIL receptor analysis.

Cell death pathways--potential therapeutic targets.

Mitochondrial fragmentation and neuronal cell death in response to the Bcl-2/Bcl-x(L)/Bcl-w antagonist ABT-737.

cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms.

The 'complexities' of life and death: death receptor signalling platforms.

A death effector domain chain DISC model reveals a crucial role for caspase-8 chain assembly in mediating apoptotic cell death.

Glucose--a sweet way to die: metabolic switching modulates tumor cell death.

Isolation, characterisation and reconstitution of cell death signalling complexes.

Notch4 Signaling Confers Susceptibility to TRAIL-Induced Apoptosis in Breast Cancer Cells.

Autophagy limits proliferation and glycolytic metabolism in acute myeloid leukemia.

In Vitro Assembly and Analysis of the Apoptosome Complex.

Activation, Isolation, and Analysis of the Death-Inducing Signaling Complex.

Biochemical Analysis of Initiator Caspase-Activating Complexes: The Apoptosome and the Death-Inducing Signaling Complex.

Co-operative and Hierarchical Binding of c-FLIP and Caspase-8: A Unified Model Defines How c-FLIP Isoforms Differentially Control Cell Fate.

Targeting cell death signalling in cancer: minimising 'Collateral damage'.

Explant Cultures of Non-Small Cell Lung Carcinoma Enable Evaluation of Primary Tumor Responses to Anticancer Therapy.

Caspase-10 Negatively Regulates Caspase-8-Mediated Cell Death, Switching the Response to CD95L in Favor of NF-κB Activation and Cell Survival.

Long-Fiber Carbon Nanotubes Replicate Asbestos-Induced Mesothelioma with Disruption of the Tumor Suppressor Gene Cdkn2a (Ink4a/Arf).

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

N-glycosylation of mouse TRAIL-R restrains TRAIL-induced apoptosis.

Asbestos: Modern Insights for Toxicology in the Era of Engineered Nanomaterials.

Evaluation of apoptosis imaging biomarkers in a genetic model of cell death.

Patient-derived explants, xenografts and organoids: 3-dimensional patient-relevant pre-clinical models in endometrial cancer.

Patient-derived explants (PDEs) as a powerful preclinical platform for anti-cancer drug and biomarker discovery.

Identification of a novel toxicophore in anti-cancer chemotherapeutics that targets mitochondrial respiratory complex I.

Exploration of Matrix Effects in Laser Ablation Inductively Coupled Plasma Mass Spectrometry Imaging of Cisplatin-Treated Tumors.

Development of a patient-derived explant model for prediction of drug responses in endometrial cancer.

Evaluating and comparing immunostaining and computational methods for spatial profiling of drug response in patient-derived explants.