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Kara Lopez-Lengowski

Center for Genomic Medicine

Massachusetts General Hospital

BIOGRAPHY

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PUBLICATIONS

Synaptic deficits in iPSC-derived cortical interneurons in schizophrenia are mediated by NLGN2 and rescued by N-acetylcysteine.

Translational psychiatry 11, 2019 | Pubmed ID: 31780643

Transcriptomic Landscape and Functional Characterization of Induced Pluripotent Stem Cell-Derived Cerebral Organoids in Schizophrenia.

JAMA psychiatry Jul, 2020 | Pubmed ID: 32186681

Transcriptome analysis and functional characterization of cerebral organoids in bipolar disorder.

Genome medicine 04, 2020 | Pubmed ID: 32306996

Can Computational Modeling Predict Disease Phenotype?

Biological psychiatry 07, 2020 | Pubmed ID: 32616198

Comparative Transcriptomic Analysis of Cerebral Organoids and Cortical Neuron Cultures Derived from Human Induced Pluripotent Stem Cells.

Stem cells and development Sep, 2020 | Pubmed ID: 32862797

INSTITUTIONS

Massachusetts General Hospital

Broad Institute of MIT & Harvard

JOVE ARTICLES

Co-Culturing Microglia and Cortical Neurons Differentiated from Human Induced Pluripotent Stem Cells

Kara Lopez-Lengowski^1,2,

Annie Kathuria^1,2,3,

Kaia Gerlovin^1,2,

Rakesh Karmacharya^{1,2,3,4,5,6,7}

¹Center for Genomic Medicine, Massachusetts General Hospital,

²Chemical Biology Program, Broad Institute of MIT & Harvard,

³Department of Psychiatry, Harvard Medical School,

⁴Schizophrenia and Bipolar Disorder Program, McLean Hospital,

⁵Program in Neuroscience, Harvard University,

⁶Program in Chemical Biology, Harvard University,

⁷, Harvard Stem Cell Institute

Neuroscience

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Kara Lopez-Lengowski

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Massachusetts General Hospital

Co-Culturing Microglia and Cortical Neurons Differentiated from Human Induced Pluripotent Stem Cells

Center for Genomic Medicine