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Guy Poirier

Department of Molecular Biology,
Medical Biochemistry,
and Pathology,
Department of Molecular Biology, Medical Biochemistry, and Pathology

Laval University Cancer Research Center

BIOGRAPHY

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PUBLICATIONS

Disruptor of telomeric silencing-1 is a chromatin-specific histone H3 methyltransferase.

The Journal of biological chemistry Aug, 2002 | Pubmed ID: 12097318

A key role for poly(ADP-ribose) polymerase 3 in ectodermal specification and neural crest development.

PloS one , 2011 | Pubmed ID: 21264220

CBX4-mediated SUMO modification regulates BMI1 recruitment at sites of DNA damage.

Nucleic acids research Jul, 2012 | Pubmed ID: 22402492

PARP activation regulates the RNA-binding protein NONO in the DNA damage response to DNA double-strand breaks.

Nucleic acids research Nov, 2012 | Pubmed ID: 22941645

Reprogramming cellular events by poly(ADP-ribose)-binding proteins.

Molecular aspects of medicine Dec, 2013 | Pubmed ID: 23268355

Germline mutations in BAP1 impair its function in DNA double-strand break repair.

Cancer research Aug, 2014 | Pubmed ID: 24894717

Emerging roles of eraser enzymes in the dynamic control of protein ADP-ribosylation.

Nature communications 03, 2019 | Pubmed ID: 30862789

Poly(ADP-ribose) polymerase-1 antagonizes DNA resection at double-strand breaks.

Nature communications 07, 2019 | Pubmed ID: 31273204

The SARS-CoV-2 Conserved Macrodomain Is a Mono-ADP-Ribosylhydrolase.

Journal of virology 01, 2021 | Pubmed ID: 33158944

Zinc finger protein E4F1 cooperates with PARP-1 and BRG1 to promote DNA double-strand break repair.

Proceedings of the National Academy of Sciences of the United States of America Mar, 2021 | Pubmed ID: 33692124

INSTITUTIONS

Laval University Cancer Research Center

CHU de Québec Research Center, CHUL Pavilion

JOVE ARTICLES

Assessment of Global DNA Double-Strand End Resection using BrdU-DNA Labeling coupled with Cell Cycle Discrimination Imaging

Julia O'Sullivan^*,1,2,

Sofiane Y. Mersaoui^*,1,2,

Guy Poirier^2,3,

Jean-Yves Masson^1,2

¹Oncology Division, Genome Stability Laboratory, CHU de Québec Research Center, HDQ Pavilion,

²Department of Molecular Biology, Medical Biochemistry, and Pathology, Laval University Cancer Research Center,

³Oncology Division, CHU de Québec Research Center, CHUL Pavilion

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Guy Poirier

Department of Molecular Biology,Medical Biochemistry,and Pathology,Department of Molecular Biology, Medical Biochemistry, and Pathology

Laval University Cancer Research Center

Assessment of Global DNA Double-Strand End Resection using BrdU-DNA Labeling coupled with Cell Cycle Discrimination Imaging

Department of Molecular Biology,
Medical Biochemistry,
and Pathology,
Department of Molecular Biology, Medical Biochemistry, and Pathology