Laboratory of Ion Channel Research (LICR),
VIB-KU Leuven Center for Brain & Disease Research,
Leuven,
Belgium & Department of Cellular and Molecular Medicine,
Laboratory of Ion Channel Research (LICR), VIB-KU Leuven Center for Brain & Disease Research, Leuven, Belgium & Department of Cellular and Molecular Medicine
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Molecular determinants of permeation through the cation channel TRPV4.
The Journal of biological chemistry Sep, 2002 | Pubmed ID: 12093812
Mg2+-dependent gating and strong inward rectification of the cation channel TRPV6.
The Journal of general physiology Mar, 2003 | Pubmed ID: 12601087
Pore structure influences gating properties of the T-type Ca2+ channel alpha1G.
The Journal of general physiology Jun, 2003 | Pubmed ID: 12743166
Extracellular Ca2+ modulates the effects of protons on gating and conduction properties of the T-type Ca2+ channel alpha1G (CaV3.1).
The Journal of general physiology Jun, 2003 | Pubmed ID: 12743167
Modulation of TRPV4 gating by intra- and extracellular Ca2+.
Cell calcium May-Jun, 2003 | Pubmed ID: 12765694
Outer pore architecture of a Ca2+-selective TRP channel.
The Journal of biological chemistry Apr, 2004 | Pubmed ID: 14736889
The principle of temperature-dependent gating in cold- and heat-sensitive TRP channels.
Nature Aug, 2004 | Pubmed ID: 15306801
Mechanism of arachidonic acid modulation of the T-type Ca2+ channel alpha1G.
The Journal of general physiology Sep, 2004 | Pubmed ID: 15314070
Decavanadate modulates gating of TRPM4 cation channels.
The Journal of physiology Nov, 2004 | Pubmed ID: 15331675
Regulation of the Ca2+ sensitivity of the nonselective cation channel TRPM4.
The Journal of biological chemistry Feb, 2005 | Pubmed ID: 15590641
The selectivity filter of the cation channel TRPM4.
The Journal of biological chemistry Jun, 2005 | Pubmed ID: 15845551
The Ca2+-activated cation channel TRPM4 is regulated by phosphatidylinositol 4,5-biphosphate.
The EMBO journal Feb, 2006 | Pubmed ID: 16424899
TRPM8-independent menthol-induced Ca2+ release from endoplasmic reticulum and Golgi.
The Journal of biological chemistry Feb, 2007 | Pubmed ID: 17142461
TRPM8 voltage sensor mutants reveal a mechanism for integrating thermal and chemical stimuli.
Nature chemical biology Mar, 2007 | Pubmed ID: 17293875
Determinants of 4 alpha-phorbol sensitivity in transmembrane domains 3 and 4 of the cation channel TRPV4.
The Journal of biological chemistry Apr, 2007 | Pubmed ID: 17341586
Gain-of-function mutations in TRPV4 cause autosomal dominant brachyolmia.
Nature genetics Aug, 2008 | Pubmed ID: 18587396
Mutations in the gene encoding the calcium-permeable ion channel TRPV4 produce spondylometaphyseal dysplasia, Kozlowski type and metatropic dysplasia.
American journal of human genetics Mar, 2009 | Pubmed ID: 19232556
Nicotine activates the chemosensory cation channel TRPA1.
Nature neuroscience Oct, 2009 | Pubmed ID: 19749751
Modulation of the cold-activated cation channel TRPM8 by surface charge screening.
The Journal of physiology Jan, 2010 | Pubmed ID: 19948654
TRPM3 is a nociceptor channel involved in the detection of noxious heat.
Neuron May, 2011 | Pubmed ID: 21555074
Ligand stoichiometry of the cold- and menthol-activated channel TRPM8.
The Journal of physiology Oct, 2011 | Pubmed ID: 21878524
Mechanisms of transient receptor potential vanilloid 1 activation and sensitization by allyl isothiocyanate.
Molecular pharmacology Sep, 2013 | Pubmed ID: 23757176
Single point mutations of aromatic residues in transmembrane helices 5 and -6 differentially affect TRPV4 activation by 4α-PDD and hypotonicity: implications for the role of the pore region in regulating TRPV4 activity.
Cell calcium Jan, 2014 | Pubmed ID: 24342753
Opening of an alternative ion permeation pathway in a nociceptor TRP channel.
Nature chemical biology Mar, 2014 | Pubmed ID: 24390427
Parents' and Adolescents' Perspectives on Parenting: Evaluating Conceptual Structure, Measurement Invariance, and Criterion Validity.
Assessment Aug, 2015 | Pubmed ID: 25225229
Externalizing Problem Behavior in Adolescence: Dopaminergic Genes in Interaction with Peer Acceptance and Rejection.
Journal of youth and adolescence Jul, 2015 | Pubmed ID: 26006708
VAMP7 regulates constitutive membrane incorporation of the cold-activated channel TRPM8.
Nature communications Feb, 2016 | Pubmed ID: 26843440
Adolescent externalizing behaviour, psychological control, and peer rejection: Transactional links and dopaminergic moderation.
The British journal of developmental psychology 09, 2017 | Pubmed ID: 28338224
Externalizing Problem Behavior in Adolescence: Parenting Interacting With DAT1 and DRD4 Genes.
Journal of research on adolescence : the official journal of the Society for Research on Adolescence 06, 2017 | Pubmed ID: 28876518
Mutations in the voltage-sensing domain affect the alternative ion permeation pathway in the TRPM3 channel.
The Journal of physiology 06, 2018 | Pubmed ID: 29604058
Δ-tetrahydrocannabivarin impairs epithelial calcium transport through inhibition of TRPV5 and TRPV6.
Pharmacological research 10, 2018 | Pubmed ID: 30170189
Gain of channel function and modified gating properties in TRPM3 mutants causing intellectual disability and epilepsy.
eLife May, 2020 | Pubmed ID: 32427099
The Zinc-Finger Domain Containing Protein ZC4H2 Interacts with TRPV4, Enhancing Channel Activity and Turnover at the Plasma Membrane.
International journal of molecular sciences May, 2020 | Pubmed ID: 32443528
Pharmacological properties of TRPM3 isoforms are determined by the length of the pore loop.
British journal of pharmacology Aug, 2020 | Pubmed ID: 32780479
Caspr2 autoantibody-associated Morvan syndrome predating thymoma relapse by 30 months.
Lung cancer (Amsterdam, Netherlands) 03, 2021 | Pubmed ID: 33485137
Noémie Luyts1,
Greetje Vande Velde2,
Matthias Vanneste1,
Helene De Bruyn1,
Annelies Janssens1,
Natalie Verstraeten3,
Thomas Voets1,
Wouter Everaerts4
1Laboratory of Ion Channel Research (LICR), VIB-KU Leuven Center for Brain & Disease Research, Leuven, Belgium & Department of Cellular and Molecular Medicine, KU Leuven,
2Biomedical MRI, Department of Imaging & Pathology, KU Leuven,
3Belgium & KU Leuven Centre of Microbial and Plant Genetics, VIB-KU Leuven Center for Microbiology, Leuven,
4Laboratory of Experimental Urology, Department of Development and Regeneration, KU Leuven