Merab Kokaia

Long-Term Effects of Myoinositol on Behavioural Seizures and Biochemical Changes Evoked by Kainic Acid Induced Epileptogenesis.

The treatment of neurological diseases under a new light: the importance of optogenetics.

Seizure-induced neurogenesis in the adult brain.

Light-activated channels in acute seizures.

An optogenetic approach in epilepsy.

VEGF receptor-2 (Flk-1) overexpression in mice counteracts focal epileptic seizures.

Novel approaches to epilepsy treatment.

Encapsulated galanin-producing cells attenuate focal epileptic seizures in the hippocampus.

Optogenetic inhibition of chemically induced hypersynchronized bursting in mice.

Global optogenetic activation of inhibitory interneurons during epileptiform activity.

Optogenetics reveal delayed afferent synaptogenesis on grafted human-induced pluripotent stem cell-derived neural progenitors.

Differential Effect of Neuropeptides on Excitatory Synaptic Transmission in Human Epileptic Hippocampus.

Translational approach for gene therapy in epilepsy: Model system and unilateral overexpression of neuropeptide Y and Y2 receptors.

Optogenetic control of human neurons in organotypic brain cultures.

Advances in the development of biomarkers for epilepsy.

Epilepsy and optogenetics: can seizures be controlled by light?

Directly Converted Human Fibroblasts Mature to Neurons and Show Long-Term Survival in Adult Rodent Hippocampus.

Altered Chloride Homeostasis Decreases the Action Potential Threshold and Increases Hyperexcitability in Hippocampal Neurons.

Dynamic interaction of local and transhemispheric networks is necessary for progressive intensification of hippocampal seizures.

Unilateral ex vivo gene therapy by GDNF in epileptic rats.

Long-Term, Targeted Delivery of GDNF from Encapsulated Cells Is Neuroprotective and Reduces Seizures in the Pilocarpine Model of Epilepsy.

Concentration- and time-dependent effects of myo-inositol on evoked epileptic afterdischarge in the hippocampus in vivo.

Disease Modification by Combinatorial Single Vector Gene Therapy: A Preclinical Translational Study in Epilepsy.

Inhibition of epileptiform activity by neuropeptide Y in brain tissue from drug-resistant temporal lobe epilepsy patients.

Leaky Optoelectrical Fiber for Optogenetic Stimulation and Electrochemical Detection of Dopamine Exocytosis from Human Dopaminergic Neurons.

Gene Therapy Vector Encoding Neuropeptide Y and Its Receptor Y2 for Future Treatment of Epilepsy: Preclinical Data in Rats.

Human stem cell-derived GABAergic neurons functionally integrate into human neuronal networks.

Human Stem Cell-Derived GABAergic Interneurons Establish Efferent Synapses onto Host Neurons in Rat Epileptic Hippocampus and Inhibit Spontaneous Recurrent Seizures.

Myo-Inositol Limits Kainic Acid-Induced Epileptogenesis in Rats.