Qun Lu

14-3-3ɛ/ζ Affects the stability of δ-catenin and regulates δ-catenin-induced dendrogenesis.

Nonreceptor tyrosine kinase c-Yes interacts with occludin during tight junction formation in canine kidney epithelial cells.

Dendrite-like process formation and cytoskeletal remodeling regulated by delta-catenin expression.

Association of nonreceptor tyrosine kinase c-yes with tight junction protein occludin by coimmunoprecipitation assay.

Abl tyrosine kinase promotes dendrogenesis by inducing actin cytoskeletal rearrangements in cooperation with Rho family small GTPases in hippocampal neurons.

Overexpression of claudin-7 decreases the paracellular Cl- conductance and increases the paracellular Na+ conductance in LLC-PK1 cells.

Increased expression of delta-catenin/neural plakophilin-related armadillo protein is associated with the down-regulation and redistribution of E-cadherin and p120ctn in human prostate cancer.

Presenilin-1 inhibits delta-catenin-induced cellular branching and promotes delta-catenin processing and turnover.

WNK4 phosphorylates ser(206) of claudin-7 and promotes paracellular Cl(-) permeability.

Delta-catenin-induced dendritic morphogenesis. An essential role of p190RhoGEF interaction through Akt1-mediated phosphorylation.

Identification of E2F1 as a positive transcriptional regulator for delta-catenin.

Anti-cancer drug induced neurotoxicity and identification of Rho pathway signaling modulators as potential neuroprotectants.

E-Cadherin negatively modulates delta-catenin-induced morphological changes and RhoA activity reduction by competing with p190RhoGEF for delta-catenin.

Increased nucleotide polymorphic changes in the 5'-untranslated region of delta-catenin (CTNND2) gene in prostate cancer.

Small molecule, non-peptide p75 ligands inhibit Abeta-induced neurodegeneration and synaptic impairment.

Identification of extracellular delta-catenin accumulation for prostate cancer detection.

Increased DJ-1 expression under oxidative stress and in Alzheimer's disease brains.

delta-Catenin promotes prostate cancer cell growth and progression by altering cell cycle and survival gene profiles.

Methodology to obtain a mixed sural nerve recording in mice.

Signaling through Rho GTPase pathway as viable drug target.

Analysis of claudin genes in pediatric patients with Bartter's syndrome.

GSK-3 phosphorylates delta-catenin and negatively regulates its stability via ubiquitination/proteosome-mediated proteolysis.

Renal salt wasting and chronic dehydration in claudin-7-deficient mice.

Xenopus delta-catenin is essential in early embryogenesis and is functionally linked to cadherins and small GTPases.

Rho kinase inhibitor Y-27632 facilitates recovery from experimental peripheral neuropathy induced by anti-cancer drug cisplatin.

Isoform- and dose-sensitive feedback interactions between paired box 6 gene and delta-catenin in cell differentiation and death.

Delta-catenin affects the localization and stability of p120-catenin by competitively interacting with E-cadherin.

Pro-oncogenic and anti-oncogenic pathways: opportunities and challenges of cancer therapy.

Delta-catenin/NPRAP: A new member of the glycogen synthase kinase-3beta signaling complex that promotes beta-catenin turnover in neurons.

δ-Catenin dysregulation in cancer: interactions with E-cadherin and beyond.

Alzheimer's disease-linked presenilin mutation (PS1M146L) induces filamin expression and γ-secretase independent redistribution.

Human homolog of Drosophila Hairy and enhancer of split 1, Hes1, negatively regulates δ-catenin (CTNND2) expression in cooperation with E2F1 in prostate cancer.

Fe3O4 nanoparticles with daunorubicin induce apoptosis through caspase 8-PARP pathway and inhibit K562 leukemia cell-induced tumor growth in vivo.

Hydroxycamptothecin-loaded Fe3O4 nanoparticles induce human lung cancer cell apoptosis through caspase-8 pathway activation and disrupt tight junctions.

Claudin-7 inhibits human lung cancer cell migration and invasion through ERK/MAPK signaling pathway.

Inflammation and disruption of the mucosal architecture in claudin-7-deficient mice.

δ-Catenin promotes E-cadherin processing and activates β-catenin-mediated signaling: Implications on human prostate cancer progression.

Small molecule targeting Cdc42-intersectin interaction disrupts Golgi organization and suppresses cell motility.

Claudin-7 increases chemosensitivity to cisplatin through the upregulation of caspase pathway in human NCI-H522 lung cancer cells.

The claudin family of proteins in human malignancy: a clinical perspective.

C-Src-mediated phosphorylation of δ-catenin increases its protein stability and the ability of inducing nuclear distribution of β-catenin.

Claudins in intestines: Distribution and functional significance in health and diseases.

Cytotoxicity of cyclometalated platinum complexes based on tridentate NCN and CNN-coordinating ligands: remarkable coordination dependence.

VASP activation via the Gα13/RhoA/PKA pathway mediates cucurbitacin-B-induced actin aggregation and cofilin-actin rod formation.

δ-Catenin, a Wnt/β-catenin modulator, reveals inducible mutagenesis promoting cancer cell survival adaptation and metabolic reprogramming.

δ-Catenin as a potential cancer biomarker.

Amelioration of cisplatin-induced experimental peripheral neuropathy by a small molecule targeting p75 NTR.

A non-tight junction function of claudin-7-Interaction with integrin signaling in suppressing lung cancer cell proliferation and detachment.

Early alterations in blood and brain RANTES and MCP-1 expression and the effect of exercise frequency in the 3xTg-AD mouse model of Alzheimer's disease.

Genetic alterations of δ-catenin/NPRAP/Neurojungin (CTNND2): functional implications in complex human diseases.

Cdc42 Signaling Pathway Inhibition as a Therapeutic Target in Ras- Related Cancers.

Rho GTPases as therapeutic targets in Alzheimer's disease.

Epithelial Mesenchymal Transition in Embryonic Development, Tissue Repair and Cancer: A Comprehensive Overview.

The effects of exercise on hypothalamic neurodegeneration of Alzheimer's disease mouse model.

Inhibition of Cdc42-intersectin interaction by small molecule ZCL367 impedes cancer cell cycle progression, proliferation, migration, and tumor growth.

Claudin-7 modulates cell-matrix adhesion that controls cell migration, invasion and attachment of human HCC827 lung cancer cells.

Therapeutic Effect of Y-27632 on Tumorigenesis and Cisplatin-Induced Peripheral Sensory Loss through RhoA-NF-κB.

Tight Junction Protein Claudin-7 Is Essential for Intestinal Epithelial Stem Cell Self-Renewal and Differentiation.

Intratumor δ-catenin heterogeneity driven by genomic rearrangement dictates growth factor dependent prostate cancer progression.

Selective axonal translation of the mRNA isoform encoding prenylated Cdc42 supports axon growth.

Pharmacological Modulators of Small GTPases of Rho Family in Neurodegenerative Diseases.

The effect of exercise on early sensorimotor performance alterations in the 3xTg-AD model of Alzheimer's disease.

TRPV4: En RhoA To a Cure?

Nanoarchitecture and molecular interactions of epithelial cell junction proteins revealed by super-resolution microscopy.