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Nuclear RNR-α antagonizes cell proliferation by directly inhibiting ZRANB3.
Nature chemical biology Oct, 2018 | Pubmed ID: 30150681
Proteomics and Beyond: Cell Decision-Making Shaped by Reactive Electrophiles.
Trends in biochemical sciences Jan, 2019 | Pubmed ID: 30327250
Weighing up the Selenocysteome Uncovers New Sec-rets.
Cell chemical biology Nov, 2018 | Pubmed ID: 30445052
Interrogating Precision Electrophile Signaling.
Trends in biochemical sciences Apr, 2019 | Pubmed ID: 30765181
Genie in a bottle: controlled release helps tame natural polypharmacology?
Current opinion in chemical biology Aug, 2019 | Pubmed ID: 30913473
Editorial overview: From the iceman to modern medicine.
Current opinion in chemical biology Jun, 2019 | Pubmed ID: 31178257
Getting the Right Grip? How Understanding Electrophile Selectivity Profiles Could Illuminate Our Understanding of Redox Signaling.
Antioxidants & redox signaling Nov, 2020 | Pubmed ID: 31578876
Post-transcriptional regulation of Nrf2-mRNA by the mRNA-binding proteins HuR and AUF1.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Dec, 2019 | Pubmed ID: 31665914
The more the merrier: how homo-oligomerization alters the interactome and function of ribonucleotide reductase.
Current opinion in chemical biology Feb, 2020 | Pubmed ID: 31734537
Clofarabine Commandeers the RNR-α-ZRANB3 Nuclear Signaling Axis.
Cell chemical biology Jan, 2020 | Pubmed ID: 31836351
REX technologies for profiling and decoding the electrophile signaling axes mediated by Rosetta Stone proteins.
Methods in enzymology , 2020 | Pubmed ID: 32046846
Electrophile Signaling and Emerging Immuno- and Neuro-modulatory Electrophilic Pharmaceuticals.
Frontiers in aging neuroscience , 2020 | Pubmed ID: 32116644
Empowering Global Chemical Biology at the Dawn of the New Decade.
ACS chemical biology Jun, 2020 | Pubmed ID: 32315151
Precision Targeting of -Null Triple-Negative Breast Tumors Guided by Electrophilic Metabolite Sensing.
ACS central science Jun, 2020 | Pubmed ID: 32607436
Where Electrophile Signaling and Covalent Ligand-Target Mining Converge.
Chimia Sep, 2020 | Pubmed ID: 32958101
An Oculus to Profile and Probe Target Engagement In Vivo: How T-REX Was Born and Its Evolution into G-REX.
Accounts of chemical research Feb, 2021 | Pubmed ID: 33228351
Science's Response to CoVID-19.
ChemMedChem Aug, 2021 | Pubmed ID: 33811458
Can Precision Electrophile Signaling Make a Meaningful and Lasting Impression in Drug Design?
Chembiochem : a European journal of chemical biology Apr, 2022 | Pubmed ID: 33826211
The mRNA-Binding Protein HuR Is a Kinetically-Privileged Electrophile Sensor.
Helvetica chimica acta May, 2020 | Pubmed ID: 34113045
Neighborhood watch: tools for defining locale-dependent subproteomes and their contextual signaling activities.
RSC chemical biology Jun, 2020 | Pubmed ID: 34458747
Wdr1 and cofilin are necessary mediators of immune-cell-specific apoptosis triggered by Tecfidera.
Nature communications Sep, 2021 | Pubmed ID: 34593792
The not so identical twins: (dis)similarities between reactive electrophile and oxidant sensing and signaling.
Chemical Society reviews Nov, 2021 | Pubmed ID: 34779447
A primer on harnessing non-enzymatic post-translational modifications for drug design.
RSC medicinal chemistry Nov, 2021 | Pubmed ID: 34825181
Function-guided proximity mapping unveils electrophilic-metabolite sensing by proteins not present in their canonical locales.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2022 | Pubmed ID: 35082156
Keap 1: The new Janus word on the block.
Bioorganic & medicinal chemistry letters Sep, 2022 | Pubmed ID: 35537607
Hiding in Plain Sight: The Issue of Hidden Variables.
ACS chemical biology Jun, 2022 | Pubmed ID: 35603432
A Journey through the Life of Professor David A. Evans.
ACS chemical biology Aug, 2022 | Pubmed ID: 35852412
Still no Rest for the Reductases: Ribonucleotide Reductase (RNR) Structure and Function: An Update.
Sub-cellular biochemistry , 2022 | Pubmed ID: 36151376
Finding a vocation for validation: taking proteomics beyond association and location.
RSC chemical biology Feb, 2023 | Pubmed ID: 36794020
Z-REX: shepherding reactive electrophiles to specific proteins expressed tissue specifically or ubiquitously, and recording the resultant functional electrophile-induced redox responses in larval fish.
Nature protocols May, 2023 | Pubmed ID: 37020146