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Department of Physiology and Cell Biology,
Faculty of Health Sciences,
Department of Physiology and Cell Biology, Faculty of Health Sciences
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A zinc-sensing receptor triggers the release of intracellular Ca2+ and regulates ion transport.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2001 | Pubmed ID: 11573009
Distribution of the zinc transporter ZnT-1 in comparison with chelatable zinc in the mouse brain.
The Journal of comparative neurology Jun, 2002 | Pubmed ID: 11984815
Postnatal regulation of ZnT-1 expression in the mouse brain.
Brain research. Developmental brain research Aug, 2002 | Pubmed ID: 12220707
A sodium zinc exchange mechanism is mediating extrusion of zinc in mammalian cells.
The Journal of biological chemistry Feb, 2004 | Pubmed ID: 14581475
Inhibitory mechanism of store-operated Ca2+ channels by zinc.
The Journal of biological chemistry Mar, 2004 | Pubmed ID: 14715648
A role for ZnT-1 in regulating cellular cation influx.
Biochemical and biophysical research communications Oct, 2004 | Pubmed ID: 15451416
Crosstalk between L-type calcium channels and ZnT-1, a new player in rate-dependent cardiac electrical remodeling.
Cell calcium Jul, 2007 | Pubmed ID: 17196651
Enhanced astrocytic nitric oxide production and neuronal modifications in the neocortex of a NOS2 mutant mouse.
PloS one Sep, 2007 | Pubmed ID: 17786214
Molecular basis for zinc transporter 1 action as an endogenous inhibitor of L-type calcium channels.
The Journal of biological chemistry Nov, 2009 | Pubmed ID: 19767393
The involvement of ZnT-1, a new modulator of cardiac L-type calcium channels, in [corrected] atrial tachycardia remodeling. [corrected].
Annals of the New York Academy of Sciences Feb, 2010 | Pubmed ID: 20201890
INO-8875, a Highly-Selective A1 Adenosine Receptor Agonist: Evaluation of Chronotropic, Dromotropic and Hemodynamic Effects in Rats.
The Journal of pharmacology and experimental therapeutics Jun, 2010 | Pubmed ID: 20494956
ZnT-1 protects HL-1 cells from simulated ischemia-reperfusion through activation of Ras-ERK signaling.
Journal of molecular medicine (Berlin, Germany) Feb, 2012 | Pubmed ID: 22193398
ZnT-1 enhances the activity and surface expression of T-type calcium channels through activation of Ras-ERK signaling.
American journal of physiology. Cell physiology Jul, 2012 | Pubmed ID: 22572848
ZnT-1 extrudes zinc from mammalian cells functioning as a Zn(2+)/H(+) exchanger.
Metallomics : integrated biometal science Sep, 2014 | Pubmed ID: 24951051
Zinc transport and the inhibition of the L-type calcium channel are two separable functions of ZnT-1.
Metallomics : integrated biometal science 03, 2017 | Pubmed ID: 28091657
Obesity, diabetes and zinc: A workshop promoting knowledge and collaboration between the UK and Israel, november 28-30, 2016 - Israel.
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) Sep, 2018 | Pubmed ID: 29895375
Metal transport mechanism of the cation diffusion facilitator (CDF) protein family - a structural perspective on human CDF (ZnT)-related diseases.
RSC chemical biology Apr, 2021 | Pubmed ID: 34458794
ZnT1 induces a crosstalk between T-type and L-type calcium channels through interactions with Raf-1 kinase and the calcium channel β2 subunit.
Metallomics : integrated biometal science May, 2023 | Pubmed ID: 37193665
Ben-Gurion University
Tomer Eli Ben Yosef1,
Raz Zarivach1,
Arie Moran2
1Department of Life Sciences and National Institute for Biotechnology in the Negev, Ben-Gurion University,
2Department of Physiology and Cell Biology, Faculty of Health Sciences, Ben-Gurion University
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