Stephen Kadlecek

Hyperpolarized 3He MRI in asthma measurements of regional ventilation following allergic sensitization and challenge in mice--preliminary results.

Measurements of regional alveolar oxygen pressure using hyperpolarized 3He MRI.

Multiple regression method for pulmonary apparent diffusion coefficient measurement by hyperpolarized 3He MRI.

Optimization of scan parameters in pulmonary partial pressure oxygen measurement by hyperpolarized 3He MRI.

Early changes of lung function and structure in an elastase model of emphysema--a hyperpolarized 3He MRI study.

Measurement of pulmonary partial pressure of oxygen and oxygen depletion rate with hyperpolarized helium-3 MRI: a preliminary reproducibility study on pig model.

A robust method for estimating regional pulmonary parameters in presence of noise.

Simultaneous measurement of pulmonary partial pressure of oxygen and apparent diffusion coefficient by hyperpolarized 3He MRI.

Quantitative assessment of lung using hyperpolarized magnetic resonance imaging.

Improved technique for measurement of regional fractional ventilation by hyperpolarized 3He MRI.

Optimal transfer of spin-order between a singlet nuclear pair and a heteronucleus.

Regional correlation of emphysematous changes in lung function and structure: a comparison between pulmonary function testing and hyperpolarized MRI metrics.

Quantitative assessment of lung ventilation and microstructure in an animal model of idiopathic pulmonary fibrosis using hyperpolarized gas MRI.

Quantitative imaging of alveolar recruitment with hyperpolarized gas MRI during mechanical ventilation.

Regional determination of oxygen uptake in rodent lungs using hyperpolarized gas and an analytical treatment of intrapulmonary gas redistribution.

A simple and low-cost device for generating hyperpolarized contrast agents using parahydrogen.

Regional function-structure relationships in lungs of an elastase murine model of emphysema.

A multislice single breath-hold scheme for imaging alveolar oxygen tension in humans.

Multislice fractional ventilation imaging in large animals with hyperpolarized gas MRI.

Determination of the singlet state lifetime of dissolved nitrous oxide from high field relaxation measurements.

Imaging the interaction of atelectasis and overdistension in surfactant-depleted lungs.

A variability study of regional alveolar oxygen tension measurement in humans using hyperpolarized (3) He MRI.

Accelerated fractional ventilation imaging with hyperpolarized Gas MRI.

Positive end-expiratory pressure increments during anesthesia in normal lung result in hysteresis and greater numbers of smaller aerated airspaces.

Regional alveolar partial pressure of oxygen measurement with parallel accelerated hyperpolarized gas MRI.

Metabolic spectroscopy of inflammation in a bleomycin-induced lung injury model using hyperpolarized 1-(13) C pyruvate.

Hyperpolarized gas diffusion MRI for the study of atelectasis and acute respiratory distress syndrome.

Alterations of regional alveolar oxygen tension in asymptomatic current smokers: assessment with hyperpolarized (3)He MR imaging.

The effect of exogenous substrate concentrations on true and apparent metabolism of hyperpolarized pyruvate in the isolated perfused lung.

Efficient production of hyperpolarized bicarbonate by chemical reaction on a DNP precursor to measure pH.

Vertical gradients in regional alveolar oxygen tension in supine human lung imaged by hyperpolarized 3He MRI.

Semiautomatic segmentation of longitudinal computed tomography images in a rat model of lung injury by surfactant depletion.

Versatile pulse sequence device to conserve hyperpolarization for NMR and MRI studies.

Oxygen-weighted Hyperpolarized (3)He MR Imaging: A Short-term Reproducibility Study in Human Subjects.

Ascorbic acid prolongs the viability and stability of isolated perfused lungs: A mechanistic study using 31P and hyperpolarized 13C nuclear magnetic resonance.

Low-temperature dynamic nuclear polarization of gases in Frozen mixtures.

Multibreath alveolar oxygen tension imaging.

Visualizing the Propagation of Acute Lung Injury.

Mild loss of lung aeration augments stretch in healthy lung regions.

Regional Fractional Ventilation by Using Multibreath Wash-in (3)He MR Imaging.

The use of hyperpolarized carbon-13 magnetic resonance for molecular imaging.

In vivo pH mapping of injured lungs using hyperpolarized [1- C]pyruvate.

A hybrid multibreath wash-in wash-out lung function quantification scheme in human subjects using hyperpolarized He MRI for simultaneous assessment of specific ventilation, alveolar oxygen tension, oxygen uptake, and air trapping.

In vivo imaging of the progression of acute lung injury using hyperpolarized [1- C] pyruvate.

Hyperpolarized gas diffusion MRI of biphasic lung inflation in short- and long-term emphysema models.

Tidal changes on CT and progression of ARDS.

Quantifying reaction kinetics of the non-enzymatic decarboxylation of pyruvate and production of peroxymonocarbonate with hyperpolarized C-NMR.

Unstable Inflation Causing Injury. Insight from Prone Position and Paired Computed Tomography Scans.

Lung Metabolism and Inflammation during Mechanical Ventilation; An Imaging Approach.

Rapid assessment of pulmonary gas transport with hyperpolarized 129Xe MRI using a 3D radial double golden-means acquisition with variable flip angles.

Assessment of Pulmonary Gas Transport in Rabbits Using Hyperpolarized Xenon-129 Magnetic Resonance Imaging.

A Model for Predicting Future FEV1 Decline in Smokers Using Hyperpolarized He Magnetic Resonance Imaging.

Assessment of flip angle-TR equivalence for standardized dissolved-phase imaging of the lung with hyperpolarized 129Xe MRI.

Multibreath Hyperpolarized He Imaging Scheme to Measure Alveolar Oxygen Tension and Apparent Diffusion Coefficient.

Measurement of Regional 2D Gas Transport Efficiency in Rabbit Lung Using Hyperpolarized 129Xe MRI.

Quantification of Ventilation and Gas Uptake in Free-Breathing Mice With Hyperpolarized Xe MRI.

Detection of lung transplant rejection in a rat model using hyperpolarized [1- C] pyruvate-based metabolic imaging.

Hyperpolarized Metabolic Imaging Detects Latent Hepatocellular Carcinoma Domains Surviving Locoregional Therapy.

Computational pipeline for estimation of small-molecule T1 relaxation times.

Investigating biases in the measurement of apparent alveolar septal wall thickness with hyperpolarized 129Xe MRI.

Pulmonary pyruvate metabolism as an index of inflammation and injury in a rat model of acute respiratory distress syndrome.

Positional Therapy and Regional Pulmonary Ventilation.

Metabolic Imaging and Biological Assessment: Platforms to Evaluate Acute Lung Injury and Inflammation.

Measuring pulmonary gas exchange using compartment-selective xenon-polarization transfer contrast (XTC) MRI.

Diminishing Efficacy of Prone Positioning With Late Application in Evolving Lung Injury.

Ventilation heterogeneity imaged by multibreath wash-ins of hyperpolarized He and Xe in healthy rabbits.

Deriving Regionally Specific Biomarkers of Emphysema and Small Airways Disease Using Variable Threshold Parametric Response Mapping on Volumetric Lung CT Images.

Radial Flow Perfusion Enables Real-Time Profiling of Cellular Metabolism at Low Oxygen Levels with Hyperpolarized C NMR Spectroscopy.

Hyperpolarized Xe MRI of the rat brain with chemical shift saturation recovery and spiral-IDEAL readout.

Simultaneous Imaging of Ventilation and Gas Exchange with Hyperpolarized Xe MRI for Monitoring Patients with Endobronchial Valve Interventions.

Imatinib alleviates lung injury and prolongs survival in ventilated rats.

Investigating the impact of RF saturation-pulse parameters on compartment-selective gas-phase depolarization with xenon polarization transfer contrast MRI.

Preclinical MRI Using Hyperpolarized Xe.

Simultaneous quantification of hyperpolarized xenon-129 ventilation and gas exchange with multi-breath xenon-polarization transfer contrast (XTC) MRI.