Mariana J. Kaplan

Peptidylarginine deiminase inhibition reduces vascular damage and modulates innate immune responses in murine models of atherosclerosis.

Detection of SLE antigens in neutrophil extracellular traps (NETs).

Neutrophil extracellular traps induce endothelial dysfunction in systemic lupus erythematosus through the activation of matrix metalloproteinase-2.

Neutrophil extracellular trap-derived enzymes oxidize high-density lipoprotein: an additional proatherogenic mechanism in systemic lupus erythematosus.

The inflammasome and lupus: another innate immune mechanism contributing to disease pathogenesis?

Peptidylarginine deiminase inhibition disrupts NET formation and protects against kidney, skin and vascular disease in lupus-prone MRL/lpr mice.

Interleukin 10 hampers endothelial cell differentiation and enhances the effects of interferon α on lupus endothelial cell progenitors.

Epigenome profiling reveals significant DNA demethylation of interferon signature genes in lupus neutrophils.

A novel image-based quantitative method for the characterization of NETosis.

The development of depressive symptoms during medical internship stress predicts worsening vascular function.

The role of neutrophils in the pathogenesis of systemic lupus erythematosus.

Inhibition of Neutrophil Extracellular Trap Formation after Stem Cell Transplant by Prostaglandin E2.

At the Bench: Neutrophil extracellular traps (NETs) highlight novel aspects of innate immune system involvement in autoimmune diseases.

Severity of Psoriasis Associates With Aortic Vascular Inflammation Detected by FDG PET/CT and Neutrophil Activation in a Prospective Observational Study.

Memory Stem T Cells in Autoimmune Disease: High Frequency of Circulating CD8+ Memory Stem Cells in Acquired Aplastic Anemia.

Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease.

Placental histology and neutrophil extracellular traps in lupus and pre-eclampsia pregnancies.

Update on cardiovascular disease in lupus.

The role of neutrophils and NETosis in autoimmune and renal diseases.

Alterations in nuclear structure promote lupus autoimmunity in a mouse model.

Dysfunction of endothelial progenitor cells is associated with the type I IFN pathway in patients with polymyositis and dermatomyositis.

Cell death in the pathogenesis of systemic lupus erythematosus and lupus nephritis.

Lupus high-density lipoprotein induces proinflammatory responses in macrophages by binding lectin-like oxidised low-density lipoprotein receptor 1 and failing to promote activating transcription factor 3 activity.

Disentangling the role of neutrophil extracellular traps in rheumatic diseases.

Multicenter Systems Analysis of Human Blood Reveals Immature Neutrophils in Males and During Pregnancy.

A role for muscarinic receptors in neutrophil extracellular trap formation and levamisole-induced autoimmunity.

Metabolic abnormalities and oxidative stress in lupus.

Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis.

Unraveling Vascular Inflammation: From Immunology to Imaging.

A High-Throughput Real-Time Imaging Technique To Quantify NETosis and Distinguish Mechanisms of Cell Death in Human Neutrophils.

Differential ubiquitination in NETs regulates macrophage responses in systemic lupus erythematosus.

Response to comment on "Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis".

Hepatocytes and neutrophils cooperatively suppress bacterial infection by differentially regulating lipocalin-2 and neutrophil extracellular traps.

Accelerated model of lupus autoimmunity and vasculopathy driven by toll-like receptor 7/9 imbalance.

Cardiovascular disease in systemic lupus erythematosus: an update.

Dysregulated neutrophil responses and neutrophil extracellular trap formation and degradation in PAPA syndrome.

Myeloid-Specific Deletion of Peptidylarginine Deiminase 4 Mitigates Atherosclerosis.

Revealing the cellular degradome by mass spectrometry analysis of proteasome-cleaved peptides.

Genome-wide DNA methylation analysis in primary antiphospholipid syndrome neutrophils.

To NET or not to NET:current opinions and state of the science regarding the formation of neutrophil extracellular traps.

Neutrophils in Rheumatoid Arthritis: Breaking Immune Tolerance and Fueling Disease.

Real-time deformability cytometry reveals sequential contraction and expansion during neutrophil priming.

Neutrophil Subsets, Platelets, and Vascular Disease in Psoriasis.

Deficiency of adenosine deaminase 2 triggers adenosine-mediated NETosis and TNF production in patients with DADA2.

Low-density granulocytes activate T cells and demonstrate a non-suppressive role in systemic lupus erythematosus.

Response to: 'Neutrophil extracellular traps and low-density granulocytes are associated with the interferon signature in systemic lupus erythematosus, but not in antiphospholipid syndrome' by van den Hoogen .

Association of lipoprotein subfractions and glycoprotein acetylation with coronary plaque burden in SLE.

The Role of Neutrophils and Neutrophil Extracellular Traps in Vascular Damage in Systemic Lupus Erythematosus.

Neutrophil extracellular traps, B cells, and type I interferons contribute to immune dysregulation in hidradenitis suppurativa.

NETched in Stone.

Deadliest catch: neutrophil extracellular traps in autoimmunity.

Transcriptomic, epigenetic, and functional analyses implicate neutrophil diversity in the pathogenesis of systemic lupus erythematosus.

NETs spread ever wider in rheumatic diseases.

The mechanics of myeloid cells.

Of larks and owls.

Technical comment on "Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis".

Erratum for Research Article "Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis" by C. Carmona-Rivera, P. M. Carlucci, E. Moore, N. Lingampalli, H. Uchtenhagen, E. James, Y. Liu, K. L. Bicker, H. Wahamma, V. Hoffman, A. I. Catrina, P. Thompson, J. H. Buckner, W. H. Robinson, D. A. Fox, M. J. Kaplan.

Interferon lambda promotes immune dysregulation and tissue inflammation in TLR7-induced lupus.

Using the circulating proteome to assess type I interferon activity in systemic lupus erythematosus.

Diapedesis-Induced Integrin Signaling via LFA-1 Facilitates Tissue Immunity by Inducing Intrinsic Complement C3 Expression in Immune Cells.

Targeting mitochondrial oxidative stress with MitoQ reduces NET formation and kidney disease in lupus-prone MRL- mice.

Macrophage metabolic reprogramming presents a therapeutic target in lupus nephritis.

Sex differences in neutrophil biology modulate response to type I interferons and immunometabolism.

Lupus-like autoimmunity and increased interferon response in patients with STAT3-deficient hyper-IgE syndrome.

Immunometabolism in the pathogenesis of systemic lupus erythematosus: an update.

Proteomic, biomechanical and functional analyses define neutrophil heterogeneity in systemic lupus erythematosus.

Oxidative DNA Damage Accelerates Skin Inflammation in Pristane-Induced Lupus Model.

Somatic Mutations in and Severe Adult-Onset Autoinflammatory Disease.

Neutrophil-mediated carbamylation promotes articular damage in rheumatoid arthritis.

Neutrophils in the Pathogenesis of Rheumatic Diseases: Fueling the Fire.

Association between anti-interferon-alpha autoantibodies and COVID-19 in systemic lupus erythematosus.

Correspondence on 'Clinical course of coronavirus disease 2019 (COVID-19) in a series of 17 patients with systemic lupus erythematosus under long-term treatment with hydroxychloroquine'.

Linking clotting and autoimmunity.

Interferon lambda in inflammation and autoimmune rheumatic diseases.

Cholesterol-Induced M4-Like Macrophages Recruit Neutrophils and Induce NETosis.

Patients with COVID-19: in the dark-NETs of neutrophils.

Phase 1 double-blind randomized safety trial of the Janus kinase inhibitor tofacitinib in systemic lupus erythematosus.

Neutrophil Dysregulation in the Pathogenesis of Systemic Lupus Erythematosus.

Neutrophils as Drivers of Immune Dysregulation in Autoimmune Diseases with Skin Manifestations.

Anti-Carbamylated LL37 Antibodies Promote Pathogenic Bone Resorption in Rheumatoid Arthritis.

Autoantibodies Present in Hidradenitis Suppurativa Correlate with Disease Severity and Promote the Release of Proinflammatory Cytokines in Macrophages.

Mitochondrial dysfunction in the erythroid compartment.

Multicenter analysis of neutrophil extracellular trap dysregulation in adult and pediatric COVID-19.

Cardiovascular disease risk and pathogenesis in systemic lupus erythematosus.

Diseases of blood vessels: Immune system involvement in vasculitis and vasculopathy.

Neutrophil phenotypes and functions in cancer: A consensus statement.

FOXM1 network in association with TREM1 suppression regulates NET formation in diabetic foot ulcers.

Single-Cell Analysis Reveals the Range of Transcriptional States of Circulating Human Neutrophils.

Peroxisome proliferator activated receptor-γ agonist pioglitazone improves vascular and metabolic dysfunction in systemic lupus erythematosus.

Neutralizing Anti‒DNase 1 and ‒DNase 1L3 Antibodies Impair Neutrophil Extracellular Traps Degradation in Hidradenitis Suppurativa.

Coexisting autoantibodies against transcription factor Sp4 are associated with decreased cancer risk in patients with dermatomyositis with anti-TIF1γ autoantibodies.

Quantification of Neutrophils Undergoing NET Formation and Distinguishing Mechanisms of Neutrophil Cell Death by Use of a High-Throughput Method.

Casting a Wide NET.

Changes in cardiorespiratory function and fatigue following 12 weeks of exercise training in women with systemic lupus erythematosus: a pilot study.

Neutrophil extracellular traps in systemic autoimmune and autoinflammatory diseases.

Low-density granulocytes in systemic autoimmunity and autoinflammation.

Distinct pathogenic roles for resident and monocyte-derived macrophages in lupus nephritis.

Spleen tyrosine kinase inhibition restores myeloid homeostasis in COVID-19.

Neutrophil extracellular trap-associated carbamylation and histones trigger osteoclast formation in rheumatoid arthritis.

Constitutively active Lyn kinase causes a cutaneous small vessel vasculitis and liver fibrosis syndrome.

Apoptosis-induced nuclear expulsion in tumor cells drives S100a4-mediated metastatic outgrowth through the RAGE pathway.

Metabolic alterations of the immune system in the pathogenesis of autoimmune diseases.

Transmission disequilibrium analysis of whole genome data in childhood-onset systemic lupus erythematosus.

Inhibition of JAK-STAT pathway corrects salivary gland inflammation and interferon driven immune activation in Sjögren's Disease.