Key Laboratory of Medical Electrophysiology of Ministry of Education,
Collaborative Innovation Center for Prevention and Treatment of Cardiovascular Disease,
Institute of Cardiovascular Research,
Key Laboratory of Medical Electrophysiology of Ministry of Education, Collaborative Innovation Center for Prevention and Treatment of Cardiovascular Disease, Institute of Cardiovascular Research
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Different Effects of Hypertension and Age on the Function of Large Conductance Calcium- and Voltage-Activated Potassium Channels in Human Mesentery Artery Smooth Muscle Cells.
Journal of the American Heart Association Sep, 2016 | Pubmed ID: 27628569
Propofol attenuates HO-induced oxidative stress and apoptosis via the mitochondria- and ER-medicated pathways in neonatal rat cardiomyocytes.
Apoptosis : an international journal on programmed cell death May, 2017 | Pubmed ID: 28176145
Multi-walled carbon nanotubes act as a chemokine and recruit macrophages by activating the PLC/IP3/CRAC channel signaling pathway.
Scientific reports Mar, 2017 | Pubmed ID: 28331181
Bidirectional Regulatory Effects of Dexmedetomidine on Porcine Coronary Tone In Vitro.
Medical science monitor : international medical journal of experimental and clinical research Apr, 2017 | Pubmed ID: 28369032
[Reconstitution of large conductance calcium-activated potassium channels into artificial planar lipid bilayers].
Sheng li xue bao : [Acta physiologica Sinica] Jun, 2017 | Pubmed ID: 28638923
Plasma Growth Differentiation Factor-15 is a Potential Biomarker for Pediatric Pulmonary Arterial Hypertension Associated with Congenital Heart Disease.
Pediatric cardiology Dec, 2017 | Pubmed ID: 28819713
Synaptobrevin-2 facilitates the trafficking and function of atrial SK2 channel.
Science China. Life sciences May, 2018 | Pubmed ID: 28853059
Environmental perturbation of the circadian clock during pregnancy leads to transgenerational mood disorder-like behaviors in mice.
Scientific reports Oct, 2017 | Pubmed ID: 28974783
Dexmedetomidine attenuates H2O2-induced neonatal rat cardiomyocytes apoptosis through mitochondria- and ER-medicated oxidative stress pathways.
Molecular medicine reports May, 2018 | Pubmed ID: 29568958
Resveratrol alleviates hypoxia/reoxygenation injury‑induced mitochondrial oxidative stress in cardiomyocytes.
Molecular medicine reports Apr, 2019 | Pubmed ID: 30816439
Downregulation of ATR decreases the responsiveness of BK channels to angiotensin II in patients with hypertension.
Journal of molecular and cellular cardiology Jun, 2019 | Pubmed ID: 30998981
Mechanisms Underlying Spontaneous Action Potential Generation Induced by Catecholamine in Pulmonary Vein Cardiomyocytes: A Simulation Study.
International journal of molecular sciences Jun, 2019 | Pubmed ID: 31207916
Pnmt-Derived Cardiomyocytes: Anatomical Localization, Function and Future Perspectives.
Frontiers in physiology , 2019 | Pubmed ID: 31354504
A Protocol for Dual Calcium-Voltage Optical Mapping in Murine Sinoatrial Preparation With Optogenetic Pacing.
Frontiers in physiology , 2019 | Pubmed ID: 31456689
Principles of Optogenetic Methods and Their Application to Cardiac Experimental Systems.
Frontiers in physiology , 2019 | Pubmed ID: 31572204
Generation of three iPSC lines (XACHi007-A, XACHi008-A, XACHi009-A) from a Chinese family with long QT syndrome type 5 with heterozygous c.226G>A (p.D76N) mutation in KCNE1gene.
Stem cell research May, 2020 | Pubmed ID: 32344329
Generation of two induced pluripotent stem cell lines (XACHi0010-A, XACHi0011-A) from a Chinese family with combined oxidative phosphorylation deficiency carrying homozygous and heterozygous C1QBP-L275F mutation.
Stem cell research Jul, 2020 | Pubmed ID: 32707487
RAD-Deficient Human Cardiomyocytes Develop Hypertrophic Cardiomyopathy Phenotypes Due to Calcium Dysregulation.
Frontiers in cell and developmental biology , 2020 | Pubmed ID: 33195237
P21‑activated kinase 1 mediates angiotensin II‑induced differentiation of human atrial fibroblasts via the JNK/c‑Jun pathway.
Molecular medicine reports Mar, 2021 | Pubmed ID: 33495806
Amelioration of Endothelial Dysfunction in Diabetes: Role of Takeda G Protein-Coupled Receptor 5.
Frontiers in pharmacology , 2021 | Pubmed ID: 33995040
Establishment of iPSC line from a Chinese infant (XACHi012-A) with Jervell and Lange-Nielsen syndrome carrying combined KCNQ1 frameshift c.431delC(p.I145Sfs*92) and nonsense c.1175G > A (p.W392X) variants and two iPSC lines from the parents (XACHi013-A, XACHi014-A).
Stem cell research May, 2021 | Pubmed ID: 34088017
Generation of induced pluripotent stem cells (iPSCs) from a Chinese infant (XACHi015-A) with type 2 Long QT syndrome carrying the heterozygous mutation c.1814C>T(p.P605L) in KCNH2.
Stem cell research Oct, 2021 | Pubmed ID: 34438161
Ventricular SK2 upregulation following angiotensin II challenge: Modulation by p21-activated kinase-1.
Journal of molecular and cellular cardiology Mar, 2022 | Pubmed ID: 34774547
A dataset of dual calcium and voltage optical mapping in healthy and hypertrophied murine hearts.
Scientific data Dec, 2021 | Pubmed ID: 34916511
Ageing Increases Cardiac Electrical Remodelling in Rats and Mice via NOX4/ROS/CaMKII-Mediated Calcium Signalling.
Oxidative medicine and cellular longevity , 2022 | Pubmed ID: 35387264
Drug-Induced Immune Thrombocytopenia Toxicity Prediction Based on Machine Learning.
Pharmaceutics Apr, 2022 | Pubmed ID: 35631529
High-Resolution 3D Heart Models of Cardiomyocyte Subpopulations in Cleared Murine Heart.
Frontiers in physiology , 2022 | Pubmed ID: 35665220
An examination of the protective effects and molecular mechanisms of curcumin, a polyphenol curcuminoid in diabetic nephropathy.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie Sep, 2022 | Pubmed ID: 36076553
Messenger Nanozyme for Reprogramming the Microenvironment of Rheumatoid Arthritis.
ACS applied materials & interfaces Jan, 2023 | Pubmed ID: 36580409
Patient-specific induced pluripotent stem cell properties implicate Ca-homeostasis in clinical arrhythmia associated with combined heterozygous and variants.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences Jun, 2023 | Pubmed ID: 37122207
Generation of cardiomyocytes from human-induced pluripotent stem cells resembling atrial cells with ability to respond to adrenoceptor agonists.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences Jun, 2023 | Pubmed ID: 37122218
Small-conductance calcium-activated potassium channels in the heart: expression, regulation and pathological implications.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences Jun, 2023 | Pubmed ID: 37122223
Leukocyte-Specific Morrbid Promotes Leukocyte Differentiation and Atherogenesis.
Research (Washington, D.C.) , 2023 | Pubmed ID: 37426471
Single-cell RNA sequencing of murine hearts for studying the development of the cardiac conduction system.
Scientific data Sep, 2023 | Pubmed ID: 37666871
Oxidative stress signaling in the pathogenesis of diabetic cardiomyopathy and the potential therapeutic role of antioxidant naringenin.
Redox report : communications in free radical research Dec, 2023 | Pubmed ID: 37747066
The characteristics and molecular targets of antiarrhythmic natural products.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie Dec, 2023 | Pubmed ID: 37897974
Dbh catecholaminergic cardiomyocytes contribute to the structure and function of the cardiac conduction system in murine heart.
Nature communications Nov, 2023 | Pubmed ID: 38016975
Yangpeng Li*,1,2,
Jun Yang*,1,
Rui Zhang1,
Tangting Chen1,
Shiyu Zhang1,
Yuqing Zheng1,
Qiang Wen3,
Tao Li1,
Xiaoqiu Tan1,2,
Ming Lei1,4,
Xianhong Ou1
1Key Laboratory of Medical Electrophysiology of Ministry of Education, Collaborative Innovation Center for Prevention and Treatment of Cardiovascular Disease, Institute of Cardiovascular Research, Southwest Medical University,
2Department of Cardiology, the Affiliated Hospital of Southwest Medical University,
3Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology,
4Department of Pharmacology, University of Oxford