Department of Bioengineering,
Department of Medicine,
Department of Bioengineering, Department of Medicine
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NF-kappaB mediates alphavbeta3 integrin-induced endothelial cell survival.
The Journal of cell biology May, 1998 | Pubmed ID: 9585425
Ectopic calcification: gathering hard facts about soft tissue mineralization.
The American journal of pathology Mar, 1999 | Pubmed ID: 10079244
Effects of cyclosporine in osteopontin null mice.
Kidney international Jul, 2002 | Pubmed ID: 12081566
Inactivation of the osteopontin gene enhances vascular calcification of matrix Gla protein-deficient mice: evidence for osteopontin as an inducible inhibitor of vascular calcification in vivo.
The Journal of experimental medicine Oct, 2002 | Pubmed ID: 12391016
Osteopontin inhibits mineral deposition and promotes regression of ectopic calcification.
The American journal of pathology Dec, 2002 | Pubmed ID: 12466120
Immunohistologic labeling of murine endothelium.
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology Mar-Apr, 2003 | Pubmed ID: 12684163
Vascular calcification: in vitro evidence for the role of inorganic phosphate.
Journal of the American Society of Nephrology : JASN Sep, 2003 | Pubmed ID: 12939385
Biomimetic peptides that engage specific integrin-dependent signaling pathways and bind to calcium phosphate surfaces.
Journal of biomedical materials research. Part A Oct, 2003 | Pubmed ID: 14517863
Characterization and analysis of osteopontin-immobilized poly(2-hydroxyethyl methacrylate) surfaces.
Journal of biomedical materials research. Part A Oct, 2003 | Pubmed ID: 14517893
Expression and function of the integrin alpha9beta1 in bovine aortic valve interstitial cells.
The Journal of heart valve disease Sep, 2003 | Pubmed ID: 14565714
Adhesive protein interactions with chitosan: consequences for valve endothelial cell growth on tissue-engineering materials.
Journal of biomedical materials research. Part A Nov, 2003 | Pubmed ID: 14566796
Regulation of cardiovascular calcification.
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology , 2004 | Pubmed ID: 15033154
Enhancing the biological activity of immobilized osteopontin using a type-1 collagen affinity coating.
Journal of biomedical materials research. Part A Jul, 2004 | Pubmed ID: 15174104
Hyaluronic acid grafting mitigates calcification of glutaraldehyde-fixed bovine pericardium.
Journal of biomedical materials research. Part A Aug, 2004 | Pubmed ID: 15227678
Mechanisms of vascular calcification in uremia.
Seminars in nephrology Sep, 2004 | Pubmed ID: 15490398
Elevated extracellular calcium levels induce smooth muscle cell matrix mineralization in vitro.
Kidney international Dec, 2004 | Pubmed ID: 15569318
The CC chemokine ligand, CCL2/MCP1, participates in macrophage fusion and foreign body giant cell formation.
The American journal of pathology Dec, 2004 | Pubmed ID: 15579457
Vascular calcification mechanisms.
Journal of the American Society of Nephrology : JASN Dec, 2004 | Pubmed ID: 15579497
Src kinase activity is required for integrin alphaVbeta3-mediated activation of nuclear factor-kappaB.
The Journal of biological chemistry Apr, 2005 | Pubmed ID: 15695822
Free fatty acid impairment of nitric oxide production in endothelial cells is mediated by IKKbeta.
Arteriosclerosis, thrombosis, and vascular biology May, 2005 | Pubmed ID: 15731493
Mitigation of ectopic calcification in osteopontin-deficient mice by exogenous osteopontin.
Calcified tissue international Apr, 2005 | Pubmed ID: 15812576
Smooth muscle cells deficient in osteopontin have enhanced susceptibility to calcification in vitro.
Cardiovascular research May, 2005 | Pubmed ID: 15820201
Regulation of vascular calcification: roles of phosphate and osteopontin.
Circulation research Apr, 2005 | Pubmed ID: 15831823
Calcification of advanced atherosclerotic lesions in the innominate arteries of ApoE-deficient mice: potential role of chondrocyte-like cells.
Arteriosclerosis, thrombosis, and vascular biology Jul, 2005 | Pubmed ID: 15845913
Esophageal epithelial cell interaction with synthetic and natural scaffolds for tissue engineering.
Biomaterials Nov, 2005 | Pubmed ID: 15913763
Controlling osteopontin orientation on surfaces to modulate endothelial cell adhesion.
Journal of biomedical materials research. Part A Jul, 2005 | Pubmed ID: 15920735
The role of osteopontin in foreign body giant cell formation.
Biomaterials Oct, 2005 | Pubmed ID: 15949549
Activation of IKKbeta by glucose is necessary and sufficient to impair insulin signaling and nitric oxide production in endothelial cells.
Journal of molecular and cellular cardiology Aug, 2005 | Pubmed ID: 15978611
Arteriosclerosis, calcium phosphate deposition and cardiovascular disease in uremia: current concepts at the bench.
Current opinion in nephrology and hypertension Nov, 2005 | Pubmed ID: 16205469
Role of the sodium-dependent phosphate cotransporter, Pit-1, in vascular smooth muscle cell calcification.
Circulation research Apr, 2006 | Pubmed ID: 16527991
Development of an esophagus acellular matrix tissue scaffold.
Tissue engineering Feb, 2006 | Pubmed ID: 16548690
Mimicking cell-cell interactions at the biomaterial-cell interface for control of stem cell differentiation.
Journal of biomedical materials research. Part A Oct, 2006 | Pubmed ID: 16758464
Osteoprotegerin inactivation accelerates advanced atherosclerotic lesion progression and calcification in older ApoE-/- mice.
Arteriosclerosis, thrombosis, and vascular biology Sep, 2006 | Pubmed ID: 16840715
Molecular mediators of alphavbeta3-induced endothelial cell survival.
Journal of vascular research , 2006 | Pubmed ID: 16888388
Mechanisms of vascular calcification.
Advances in chronic kidney disease Jan, 2007 | Pubmed ID: 17200044
Sodium-dependent phosphate cotransporters and vascular calcification.
Current opinion in nephrology and hypertension Jul, 2007 | Pubmed ID: 17565274
Delivery of non-viral gene carriers from sphere-templated fibrin scaffolds for sustained transgene expression.
Biomaterials Nov, 2007 | Pubmed ID: 17675152
Osteopontin: a multifunctional molecule regulating chronic inflammation and vascular disease.
Arteriosclerosis, thrombosis, and vascular biology Nov, 2007 | Pubmed ID: 17717292
A fibrinogen-based precision microporous scaffold for tissue engineering.
Biomaterials Dec, 2007 | Pubmed ID: 17765302
BMP-2 promotes phosphate uptake, phenotypic modulation, and calcification of human vascular smooth muscle cells.
Atherosclerosis Aug, 2008 | Pubmed ID: 18179800
Role of carbonic anhydrase II in ectopic calcification.
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology , 2009 | Pubmed ID: 18402839
The influence of surface mineral and osteopontin on the formation and function of murine bone marrow-derived osteoclasts.
Journal of materials science. Materials in medicine Oct, 2008 | Pubmed ID: 18483788
Crosslinking of an oesophagus acellular matrix tissue scaffold.
Journal of tissue engineering and regenerative medicine Aug, 2008 | Pubmed ID: 18618611
Microporous nanofibrous fibrin-based scaffolds for bone tissue engineering.
Biomaterials Oct, 2008 | Pubmed ID: 18640716
Methods to promote Notch signaling at the biomaterial interface and evaluation in a rafted organ culture model.
Journal of biomedical materials research. Part A Nov, 2009 | Pubmed ID: 18985776
Osteoprotegerin and RANKL differentially regulate angiogenesis and endothelial cell function.
Angiogenesis , 2009 | Pubmed ID: 19105036
The emerging role of phosphate in vascular calcification.
Kidney international May, 2009 | Pubmed ID: 19145240
Smooth muscle cells give rise to osteochondrogenic precursors and chondrocytes in calcifying arteries.
Circulation research Mar, 2009 | Pubmed ID: 19197075
Phosphate feeding induces arterial medial calcification in uremic mice: role of serum phosphorus, fibroblast growth factor-23, and osteopontin.
Kidney international Jun, 2009 | Pubmed ID: 19322138
Immobilization of alkaline phosphatase on microporous nanofibrous fibrin scaffolds for bone tissue engineering.
Biomaterials Sep, 2009 | Pubmed ID: 19501906
The role of osteopontin in inflammatory processes.
Journal of cell communication and signaling Dec, 2009 | Pubmed ID: 19798593
Generation of mouse conditional and null alleles of the type III sodium-dependent phosphate cotransporter PiT-1.
Genesis (New York, N.Y. : 2000) Dec, 2009 | Pubmed ID: 19882669
Discoidin domain receptor-1 deficiency attenuates atherosclerotic calcification and smooth muscle cell-mediated mineralization.
The American journal of pathology Dec, 2009 | Pubmed ID: 19893047
Vitamin D receptor activators induce an anticalcific paracrine program in macrophages: requirement of osteopontin.
Arteriosclerosis, thrombosis, and vascular biology Feb, 2010 | Pubmed ID: 19948844
Characterization of mandibular bone in a mouse model of chronic kidney disease.
Journal of periodontology Feb, 2010 | Pubmed ID: 20151810
Runx2/Cbfa1, but not loss of myocardin, is required for smooth muscle cell lineage reprogramming toward osteochondrogenesis.
Journal of cellular biochemistry Jul, 2010 | Pubmed ID: 20564193
Phosphate and vascular calcification: Emerging role of the sodium-dependent phosphate co-transporter PiT-1.
Thrombosis and haemostasis Sep, 2010 | Pubmed ID: 20664908
Matrix remodeling in vascular calcification associated with chronic kidney disease.
Journal of the American Society of Nephrology : JASN Oct, 2010 | Pubmed ID: 20798261
Elastin degradation and vascular smooth muscle cell phenotype change precede cell loss and arterial medial calcification in a uremic mouse model of chronic kidney disease.
The American journal of pathology Feb, 2011 | Pubmed ID: 21281809
Direct effects of phosphate on vascular cell function.
Advances in chronic kidney disease Mar, 2011 | Pubmed ID: 21406295
Arterial calcification in chronic kidney disease: key roles for calcium and phosphate.
Circulation research Sep, 2011 | Pubmed ID: 21885837
Combination of Sleeping Beauty transposition and chemically induced dimerization selection for robust production of engineered cells.
Nucleic acids research Jun, 2012 | Pubmed ID: 22402491
Sources of cells that contribute to atherosclerotic intimal calcification: an in vivo genetic fate mapping study.
Cardiovascular research Jun, 2012 | Pubmed ID: 22436847
Engineering biomaterials to integrate and heal: the biocompatibility paradigm shifts.
Biotechnology and bioengineering Aug, 2012 | Pubmed ID: 22592568
Vitamin D receptor agonists increase klotho and osteopontin while decreasing aortic calcification in mice with chronic kidney disease fed a high phosphate diet.
Kidney international Dec, 2012 | Pubmed ID: 22932118
RANKL enhances macrophage paracrine pro-calcific activity in high phosphate-treated smooth muscle cells: dependence on IL-6 and TNF-α.
Journal of vascular research , 2012 | Pubmed ID: 22948607
High phosphate feeding promotes mineral and bone abnormalities in mice with chronic kidney disease.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association Jan, 2013 | Pubmed ID: 23045434
Smooth muscle cell plasticity: fact or fiction?
Circulation research Jan, 2013 | Pubmed ID: 23093573
Osteopontin mediates macrophage chemotaxis via α4 and α9 integrins and survival via the α4 integrin.
Journal of cellular biochemistry May, 2013 | Pubmed ID: 23192608
Prevascularized microtemplated fibrin scaffolds for cardiac tissue engineering applications.
Tissue engineering. Part A Apr, 2013 | Pubmed ID: 23317311
Fibroblast growth factor 23 is not associated with and does not induce arterial calcification.
Kidney international Jun, 2013 | Pubmed ID: 23389416
Vascular calcification: an update on mechanisms and challenges in treatment.
Calcified tissue international Oct, 2013 | Pubmed ID: 23456027
Sodium-dependent phosphate cotransporters and phosphate-induced calcification of vascular smooth muscle cells: redundant roles for PiT-1 and PiT-2.
Arteriosclerosis, thrombosis, and vascular biology Nov, 2013 | Pubmed ID: 23968976
An inducible, ligand-independent receptor activator of NF-κB gene to control osteoclast differentiation from monocytic precursors.
PloS one , 2013 | Pubmed ID: 24386387
Engineered biomaterials control differentiation and proliferation of human-embryonic-stem-cell-derived cardiomyocytes via timed Notch activation.
Stem cell reports Mar, 2014 | Pubmed ID: 24672751
Loss of PiT-1 results in abnormal endocytosis in the yolk sac visceral endoderm.
Mechanisms of development Aug, 2014 | Pubmed ID: 25138534
A current understanding of vascular calcification in CKD.
American journal of physiology. Renal physiology Oct, 2014 | Pubmed ID: 25143458
Calcific aortic valve disease: a consensus summary from the Alliance of Investigators on Calcific Aortic Valve Disease.
Arteriosclerosis, thrombosis, and vascular biology Nov, 2014 | Pubmed ID: 25189570
Phosphate uptake-independent signaling functions of the type III sodium-dependent phosphate transporter, PiT-1, in vascular smooth muscle cells.
Experimental cell research Apr, 2015 | Pubmed ID: 25684711
Runx2 Expression in Smooth Muscle Cells Is Required for Arterial Medial Calcification in Mice.
The American journal of pathology Jul, 2015 | Pubmed ID: 25987250
SLC20A2 Deficiency in Mice Leads to Elevated Phosphate Levels in Cerbrospinal Fluid and Glymphatic Pathway-Associated Arteriolar Calcification, and Recapitulates Human Idiopathic Basal Ganglia Calcification.
Brain pathology (Zurich, Switzerland) 01, 2017 | Pubmed ID: 26822507
Slc20a2 deficiency results in fetal growth restriction and placental calcification associated with thickened basement membranes and novel CD13 and lamininα1 expressing cells.
Reproductive biology Mar, 2016 | Pubmed ID: 26952749
Osteopontin protects against high phosphate-induced nephrocalcinosis and vascular calcification.
Kidney international May, 2016 | Pubmed ID: 27083280
Runx2 deletion in smooth muscle cells inhibits vascular osteochondrogenesis and calcification but not atherosclerotic lesion formation.
Cardiovascular research Nov, 2016 | Pubmed ID: 27671804
Vascular calcification in CKD-MBD: Roles for phosphate, FGF23, and Klotho.
Bone Jul, 2017 | Pubmed ID: 27847254
Osteoclast precursors do not express CD68: results from CD68 promoter-driven RANK transgenic mice.
FEBS letters Mar, 2017 | Pubmed ID: 28173622
Noncanonical Wnts at the Cusp of Fibrocalcific Signaling Processes in Human Calcific Aortic Valve Disease.
Arteriosclerosis, thrombosis, and vascular biology Mar, 2017 | Pubmed ID: 28228443
Loss of PiT-2 results in abnormal bone development and decreased bone mineral density and length in mice.
Biochemical and biophysical research communications Jan, 2018 | Pubmed ID: 29133259
Role of smooth muscle cells in vascular calcification: implications in atherosclerosis and arterial stiffness.
Cardiovascular research Mar, 2018 | Pubmed ID: 29514202
Increased Calcific Aortic Valve Disease in response to a diabetogenic, procalcific diet in the LDLrApoB mouse model.
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology , 2018 | Pubmed ID: 29539583
PiT-2, a type III sodium-dependent phosphate transporter, protects against vascular calcification in mice with chronic kidney disease fed a high-phosphate diet.
Kidney international Oct, 2018 | Pubmed ID: 30041812
Slc20a1/Pit1 and Slc20a2/Pit2 are essential for normal skeletal myofiber function and survival.
Scientific reports Feb, 2020 | Pubmed ID: 32080237
Adapter Protein RapGEF1 Is Required for ERK1/2 Signaling in Response to Elevated Phosphate in Vascular Smooth Muscle Cells.
Journal of vascular research , 2021 | Pubmed ID: 33951626
Engineered osteoclasts resorb necrotic alveolar bone in anti-RANKL antibody-treated mice.
Bone Dec, 2021 | Pubmed ID: 34375732
Role of Runx2 in Calcific Aortic Valve Disease in Mouse Models.
Frontiers in cardiovascular medicine , 2021 | Pubmed ID: 34778386
Dissecting specific Wnt components governing osteogenic differentiation potential by human periodontal ligament stem cells through interleukin-6.
Scientific reports Jun, 2023 | Pubmed ID: 37270571
Comparison of osteoclast differentiation protocols from human induced pluripotent stem cells of different tissue origins.
Research square Jul, 2023 | Pubmed ID: 37461708
Comparison of osteoclast differentiation protocols from human induced pluripotent stem cells of different tissue origins.
Stem cell research & therapy Nov, 2023 | Pubmed ID: 37936199