Laboratory of Translational Cancer Genomics,
Biomedical Center,
Faculty of Medicine in Pilsen,
Laboratory of Translational Cancer Genomics, Biomedical Center, Faculty of Medicine in Pilsen
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A gene-wide investigation on polymorphisms in the taste receptor 2R14 (TAS2R14) and susceptibility to colorectal cancer.
BMC medical genetics Jun, 2010 | Pubmed ID: 20534144
Polymorphisms of genes coding for ghrelin and its receptor in relation to colorectal cancer risk: a two-step gene-wide case-control study.
BMC gastroenterology Sep, 2010 | Pubmed ID: 20920174
Association between TAS2R38 gene polymorphisms and colorectal cancer risk: a case-control study in two independent populations of Caucasian origin.
PloS one , 2011 | Pubmed ID: 21674048
A comprehensive investigation on common polymorphisms in the MDR1/ABCB1 transporter gene and susceptibility to colorectal cancer.
PloS one , 2012 | Pubmed ID: 22396794
Shared ancestral susceptibility to colorectal cancer and other nutrition related diseases.
BMC medical genetics Oct, 2012 | Pubmed ID: 23036011
Single nucleotide polymorphisms within interferon signaling pathway genes are associated with colorectal cancer susceptibility and survival.
PloS one , 2014 | Pubmed ID: 25350395
Structural chromosomal aberrations as potential risk markers in incident cancer patients.
Mutagenesis Jul, 2015 | Pubmed ID: 25800034
Interactions of DNA repair gene variants modulate chromosomal aberrations in healthy subjects.
Carcinogenesis Nov, 2015 | Pubmed ID: 26354780
Genetic variation in the major mitotic checkpoint genes associated with chromosomal aberrations in healthy humans.
Cancer letters Oct, 2016 | Pubmed ID: 27424524
Genomewide association study on monoclonal gammopathy of unknown significance (MGUS).
European journal of haematology Jul, 2017 | Pubmed ID: 28375557
Bleomycin-induced chromosomal damage and shortening of telomeres in peripheral blood lymphocytes of incident cancer patients.
Genes, chromosomes & cancer Feb, 2018 | Pubmed ID: 29052312
Investigation of single and synergic effects of NLRC5 and PD-L1 variants on the risk of colorectal cancer.
PloS one , 2018 | Pubmed ID: 29408916
Short article: Influence of regulatory NLRC5 variants on colorectal cancer survival and 5-fluorouracil-based chemotherapy.
European journal of gastroenterology & hepatology Aug, 2018 | Pubmed ID: 29762254
Coding variants in NOD-like receptors: An association study on risk and survival of colorectal cancer.
PloS one , 2018 | Pubmed ID: 29928061
Genetic variation associated with chromosomal aberration frequency: A genome-wide association study.
Environmental and molecular mutagenesis Jan, 2019 | Pubmed ID: 30368896
Genetic variation of acquired structural chromosomal aberrations.
Mutation research. Genetic toxicology and environmental mutagenesis Dec, 2018 | Pubmed ID: 30389156
Genome-wide association study of monoclonal gammopathy of unknown significance (MGUS): comparison with multiple myeloma.
Leukemia Jul, 2019 | Pubmed ID: 30737484
Single nucleotide polymorphisms within MUC4 are associated with colorectal cancer survival.
PloS one , 2019 | Pubmed ID: 31091244
Distinct pathways associated with chromosomal aberration frequency in a cohort exposed to genotoxic compounds compared to general population.
Mutagenesis Dec, 2019 | Pubmed ID: 31586183
Eight novel loci implicate shared genetic etiology in multiple myeloma, AL amyloidosis, and monoclonal gammopathy of unknown significance.
Leukemia Apr, 2020 | Pubmed ID: 31695157
Epistatic effect of TLR3 and cGAS-STING-IKKε-TBK1-IFN signaling variants on colorectal cancer risk.
Cancer medicine Feb, 2020 | Pubmed ID: 31869529
Genetic predisposition for multiple myeloma.
Leukemia Mar, 2020 | Pubmed ID: 31913320
TERT promoter mutations in actinic keratosis before and after treatment.
International journal of cancer May, 2020 | Pubmed ID: 31970758
Association between tumor characteristics and second primary cancers with cutaneous melanoma survival: A nationwide cohort study.
Pigment cell & melanoma research Jul, 2020 | Pubmed ID: 32012479
Second Primary Cancers in Melanoma Patients Critically Shorten Survival.
Clinical epidemiology , 2020 | Pubmed ID: 32158273
Identification of Familial Hodgkin Lymphoma Predisposing Genes Using Whole Genome Sequencing.
Frontiers in bioengineering and biotechnology , 2020 | Pubmed ID: 32211398
Determining the Appropriate Risk-Adapted Screening Age for Familial Breast Cancer.
JAMA oncology Jun, 2020 | Pubmed ID: 32379276
Search for multiple myeloma risk factors using Mendelian randomization.
Blood advances May, 2020 | Pubmed ID: 32433745
A Germline Mutation in the Gene Is a Candidate for Familial Non-Medullary Thyroid Cancer.
Cancers Jun, 2020 | Pubmed ID: 32492864
Genomic imprinting analyses identify maternal effects as a cause of phenotypic variability in type 1 diabetes and rheumatoid arthritis.
Scientific reports Jul, 2020 | Pubmed ID: 32665606
Familial risks between Graves disease and Hashimoto thyroiditis and other autoimmune diseases in the population of Sweden.
Journal of translational autoimmunity , 2020 | Pubmed ID: 32743538
Informing patients about their mutation tests: CDKN2A c.256G>A in melanoma as an example.
Hereditary cancer in clinical practice , 2020 | Pubmed ID: 32760473
Incidence Differences Between First Primary Cancers and Second Primary Cancers Following Skin Squamous Cell Carcinoma as Etiological Clues.
Clinical epidemiology , 2020 | Pubmed ID: 32821171
Rate differences between first and second primary cancers may outline immune dysfunction as a key risk factor.
Cancer medicine Nov, 2020 | Pubmed ID: 32960498
Cancer Predisposition Genes in Cancer-Free Families.
Cancers Sep, 2020 | Pubmed ID: 32992489
Chromosomal damage and telomere length in peripheral blood lymphocytes of cancer patients.
Oncology reports Nov, 2020 | Pubmed ID: 33000239
Familial associations between autoimmune hepatitis and primary biliary cholangitis and other autoimmune diseases.
PloS one , 2020 | Pubmed ID: 33079961
Familial associations for Addison's disease and between Addison's disease and other autoimmune diseases.
Endocrine connections Nov, 2020 | Pubmed ID: 33112839
Impact of genetic polymorphisms in kinetochore and spindle assembly genes on chromosomal aberration frequency in healthy humans.
Mutation research. Genetic toxicology and environmental mutagenesis , 2020 | Pubmed ID: 33198934
Familial associations for rheumatoid autoimmune diseases.
Rheumatology advances in practice , 2020 | Pubmed ID: 33241174
Familial risks between giant cell arteritis and Takayasu arteritis and other autoimmune diseases in the population of Sweden.
Scientific reports Nov, 2020 | Pubmed ID: 33257751
Telomere length in peripheral blood lymphocytes related to genetic variation in telomerase, prognosis and clinicopathological features in breast cancer patients.
Mutagenesis Dec, 2020 | Pubmed ID: 33367858
A rare large duplication of MLH1 identified in Lynch syndrome.
Hereditary cancer in clinical practice Jan, 2021 | Pubmed ID: 33468175
Familial Risks between Pernicious Anemia and Other Autoimmune Diseases in the Population of Sweden.
Autoimmune diseases , 2021 | Pubmed ID: 33505716
Characterization of rare germline variants in familial multiple myeloma.
Blood cancer journal Feb, 2021 | Pubmed ID: 33583942
Whole Exome Sequencing Identifies and Genes as Potentially Cancer Predisposing in Familial Colorectal Cancer.
International journal of molecular sciences Feb, 2021 | Pubmed ID: 33673279
DNA repair gene polymorphisms and chromosomal aberrations in healthy, nonsmoking population.
DNA repair May, 2021 | Pubmed ID: 33676360
Whole Genome Sequencing Prioritizes , and as Possible Predisposition Genes for Familial Non-Medullary Thyroid Cancer.
Frontiers in endocrinology , 2021 | Pubmed ID: 33692755
Polymorphisms within Autophagy-Related Genes Influence the Risk of Developing Colorectal Cancer: A Meta-Analysis of Four Large Cohorts.
Cancers Mar, 2021 | Pubmed ID: 33809172
A Novel Low-Risk Germline Variant in the SH2 Domain of the SRC Gene Affects Multiple Pathways in Familial Colorectal Cancer.
Journal of personalized medicine Apr, 2021 | Pubmed ID: 33916261
Incidence trends in bladder and lung cancers between Denmark, Finland and Sweden may implicate oral tobacco (snuff/snus) as a possible risk factor.
BMC cancer May, 2021 | Pubmed ID: 34034676
Incidence trends in lung and bladder cancers in the Nordic Countries before and after the smoking epidemic.
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) May, 2022 | Pubmed ID: 34074862
Bladder and upper urinary tract cancers as first and second primary cancers.
Cancer reports (Hoboken, N.J.) Dec, 2021 | Pubmed ID: 34114732
Family history of early onset acute lymphoblastic leukemia is suggesting genetic associations.
Scientific reports Jun, 2021 | Pubmed ID: 34117277
Progress in survival in renal cell carcinoma through 50 years evaluated in Finland and Sweden.
PloS one , 2021 | Pubmed ID: 34157049
DNA Repair Gene Polymorphisms and Chromosomal Aberrations in Exposed Populations.
Frontiers in genetics , 2021 | Pubmed ID: 34220964
Search for AL amyloidosis risk factors using Mendelian randomization.
Blood advances Jul, 2021 | Pubmed ID: 34228109
Second Primary Cancers After Gastric Cancer, and Gastric Cancer as Second Primary Cancer.
Clinical epidemiology , 2021 | Pubmed ID: 34239328
Survival in colon and rectal cancers in Finland and Sweden through 50 years.
BMJ open gastroenterology Jul, 2021 | Pubmed ID: 34272211
Second Primary Cancers After Kidney Cancers, and Kidney Cancers as Second Primary Cancers.
European urology open science Feb, 2021 | Pubmed ID: 34337496
Combinations of Low-Frequency Genetic Variants Might Predispose to Familial Pancreatic Cancer.
Journal of personalized medicine Jul, 2021 | Pubmed ID: 34357098
Second Primary Cancers After Liver, Gallbladder and Bile Duct Cancers, and These Cancers as Second Primary Cancers.
Clinical epidemiology , 2021 | Pubmed ID: 34377034
Epidemiology, genetics and treatment of multiple myeloma and precursor diseases.
International journal of cancer Dec, 2021 | Pubmed ID: 34398972
Family History of Head and Neck Cancers.
Cancers Aug, 2021 | Pubmed ID: 34439270
Incidence, mortality and survival in multiple myeloma compared to other hematopoietic neoplasms in Sweden up to year 2016.
Scientific reports Aug, 2021 | Pubmed ID: 34446811
Familial Risks and Proportions Describing Population Landscape of Familial Cancer.
Cancers Aug, 2021 | Pubmed ID: 34503195
Types of second primary cancer influence overall survival in cutaneous melanoma.
BMC cancer Oct, 2021 | Pubmed ID: 34663263
Incidence, mortality and survival in malignant pleural mesothelioma before and after asbestos in Denmark, Finland, Norway and Sweden.
BMC cancer Nov, 2021 | Pubmed ID: 34749677
Prevalence of the GFI1-36N SNP in Multiple Myeloma Patients and Its Impact on the Prognosis.
Frontiers in oncology , 2021 | Pubmed ID: 34760702
The Asthma Family Tree: Evaluating Associations Between Childhood, Parental, and Grandparental Asthma in Seven Chinese Cities.
Frontiers in pediatrics , 2021 | Pubmed ID: 34778126
Survival in bladder and upper urinary tract cancers in Finland and Sweden through 50 years.
PloS one , 2022 | Pubmed ID: 34982793
Functional dissection of inherited non-coding variation influencing multiple myeloma risk.
Nature communications Jan, 2022 | Pubmed ID: 35013207
T- and B-Cells in the Inner Invasive Margin of Hepatocellular Carcinoma after Resection Associate with Favorable Prognosis.
Cancers Jan, 2022 | Pubmed ID: 35158872
Germline Variants of and Predispose to Familial Colorectal Cancer.
Cancers Jan, 2022 | Pubmed ID: 35158942
Whole-Exome Sequencing Identifies a Novel Germline Variant in Gene in Familial Colorectal Cancer.
International journal of molecular sciences Jan, 2022 | Pubmed ID: 35163215
Long-term incidence and survival trends in cancer of the gallbladder and extrahepatic bile ducts in Denmark, Finland, Norway and Sweden with etiological implications related to Thorotrast.
International journal of cancer Jul, 2022 | Pubmed ID: 35213036
Incidence and survival in oral and pharyngeal cancers in Finland and Sweden through half century.
BMC cancer Mar, 2022 | Pubmed ID: 35236321
Genome-wide meta-analysis of monoclonal gammopathy of undetermined significance (MGUS) identifies risk loci impacting IRF-6.
Blood cancer journal Apr, 2022 | Pubmed ID: 35418122
Long-term incidence in hepatocellular carcinoma and intrahepatic bile duct cancer in Denmark, Finland, Norway and Sweden, role of Thorotrast?
International journal of cancer Aug, 2022 | Pubmed ID: 35429352
Familial Risks for Liver, Gallbladder and Bile Duct Cancers and for Their Risk Factors in Sweden, a Low-Incidence Country.
Cancers Apr, 2022 | Pubmed ID: 35454845
Cervical, vaginal and vulvar cancer incidence and survival trends in Denmark, Finland, Norway and Sweden with implications to treatment.
BMC cancer Apr, 2022 | Pubmed ID: 35473606
Whole exome sequencing identifies novel germline variants of SLC15A4 gene as potentially cancer predisposing in familial colorectal cancer.
Molecular genetics and genomics : MGG Jul, 2022 | Pubmed ID: 35562597
Validation and functional characterization of GWAS-identified variants for chronic lymphocytic leukemia: a CRuCIAL study.
Blood cancer journal May, 2022 | Pubmed ID: 35581176
Incidence and survival in laryngeal and lung cancers in Finland and Sweden through a half century.
PloS one , 2022 | Pubmed ID: 35622857
Does a Multiple Myeloma Polygenic Risk Score Predict Overall Survival of Patients with Myeloma?
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology Sep, 2022 | Pubmed ID: 35700034
Family history of any cancer for childhood leukemia patients in Sweden.
EJHaem Aug, 2021 | Pubmed ID: 35844716
CTNNB1 mutations, TERT polymorphism and CD8+ cell densities in resected hepatocellular carcinoma are associated with longer time to recurrence.
BMC cancer Aug, 2022 | Pubmed ID: 35962322
Genetic signature of differentiated thyroid carcinoma susceptibility: a machine learning approach.
European thyroid journal Oct, 2022 | Pubmed ID: 35976137
Survival trends in solid cancers in the Nordic countries through 50 years.
European journal of cancer (Oxford, England : 1990) Nov, 2022 | Pubmed ID: 36096040
Personal comorbidities and their subsequent risks for liver, gallbladder and bile duct cancers.
International journal of cancer Mar, 2023 | Pubmed ID: 36196489
Monitoring of telomere dynamics in peripheral blood leukocytes in relation to colorectal cancer patients' outcomes.
Frontiers in oncology , 2022 | Pubmed ID: 36203452
Survival trends in hematological malignancies in the Nordic countries through 50 years.
Blood cancer journal Nov, 2022 | Pubmed ID: 36336699
Long-term survival trends for primary liver and pancreatic cancers in the Nordic countries.
JHEP reports : innovation in hepatology Dec, 2022 | Pubmed ID: 36352895
Long Non-Coding RNA and microRNA Interplay in Colorectal Cancer and Their Effect on the Tumor Microenvironment.
Cancers Nov, 2022 | Pubmed ID: 36358867
Overview on population screening for carriers with germline BRCA mutation in China.
Frontiers in oncology , 2022 | Pubmed ID: 36439508
Incidence, Mortality and Survival Trends in Breast Cancers Coincident with Introduction of Mammography in the Nordic Countries.
Cancers Nov, 2022 | Pubmed ID: 36497389
Activated Hepatic Stellate Cells in Hepatocellular Carcinoma: Their Role as a Potential Target for Future Therapies.
International journal of molecular sciences Dec, 2022 | Pubmed ID: 36499616
Author Correction: Functional dissection of inherited non-coding variation influencing multiple myeloma risk.
Nature communications Dec, 2022 | Pubmed ID: 36513657
Long-term survival trends in solid cancers in the Nordic countries marking timing of improvements.
International journal of cancer May, 2023 | Pubmed ID: 36571455
Investigation of Rare Non-Coding Variants in Familial Multiple Myeloma.
Cells Dec, 2022 | Pubmed ID: 36611892
An investigation of DNA damage and DNA repair in chemical carcinogenesis triggered by small-molecule xenobiotics and in cancer: Thirty years with the comet assay.
Mutation research. Genetic toxicology and environmental mutagenesis Jan, 2023 | Pubmed ID: 36669813
Autoimmune diseases as comorbidities for liver, gallbladder, and biliary duct cancers in Sweden.
Cancer Jan, 2023 | Pubmed ID: 36715017
Survival in Colon, Rectal and Small Intestinal Cancers in the Nordic Countries through a Half Century.
Cancers Feb, 2023 | Pubmed ID: 36765946
Response to letter entitled: Re: Survival trends in solid cancers in the Nordic countries through 50 years.
European journal of cancer (Oxford, England : 1990) Apr, 2023 | Pubmed ID: 36792396
Survival in hematological malignancies in the Nordic countries through a half century with correlation to treatment.
Leukemia Apr, 2023 | Pubmed ID: 36828868
Survival in gastric and esophageal cancers in the Nordic countries through a half century.
Cancer medicine May, 2023 | Pubmed ID: 36846972
Are population level familial risks and germline genetics meeting each other?
Hereditary cancer in clinical practice Mar, 2023 | Pubmed ID: 36882784
GWAS-Identified Variants for Obesity Do Not Influence the Risk of Developing Multiple Myeloma: A Population-Based Study and Meta-Analysis.
International journal of molecular sciences Mar, 2023 | Pubmed ID: 37047000
Re: Mark N. Brook, Holly Ní Raghallaigh, Koveela Govindasami, et al. Family History of Prostate Cancer and Survival Outcomes in the UK Genetic Prostate Cancer Study. Eur Urol 2023;83:257-66.
European urology Jul, 2023 | Pubmed ID: 37061447
Survival in melanoma in the nordic countries into the era of targeted and immunological therapies.
European journal of cancer (Oxford, England : 1990) Jun, 2023 | Pubmed ID: 37068406
Survival in Lung Cancer in the Nordic Countries Through A Half Century.
Clinical epidemiology , 2023 | Pubmed ID: 37153073
Theranostics Nanomedicine Applications for Colorectal Cancer and Metastasis: Recent Advances.
International journal of molecular sciences Apr, 2023 | Pubmed ID: 37175627
Do GWAS-Identified Risk Variants for Chronic Lymphocytic Leukemia Influence Overall Patient Survival and Disease Progression?
International journal of molecular sciences Apr, 2023 | Pubmed ID: 37175717
Polymorphisms within Autophagy-Related Genes as Susceptibility Biomarkers for Multiple Myeloma: A Meta-Analysis of Three Large Cohorts and Functional Characterization.
International journal of molecular sciences May, 2023 | Pubmed ID: 37239846
Survival in Kidney and Bladder Cancers in Four Nordic Countries through a Half Century.
Cancers May, 2023 | Pubmed ID: 37345119
Population-Attributable Fractions of Personal Comorbidities for Liver, Gallbladder, and Bile Duct Cancers.
Cancers Jun, 2023 | Pubmed ID: 37370702
Association between intake of the n-3 polyunsaturated fatty acid docosahexaenoic acid (n-3 PUFA DHA) and reduced risk of ovarian cancer: A systematic Mendelian Randomization study.
Clinical nutrition (Edinburgh, Scotland) Aug, 2023 | Pubmed ID: 37421851
Survival, Incidence, and Mortality Trends in Female Cancers in the Nordic Countries.
Obstetrics and gynecology international , 2023 | Pubmed ID: 37457920
Conditional survival in breast cancer up to 10 years in the Nordic countries.
Cancer medicine Sep, 2023 | Pubmed ID: 37578395
Conditional Survival in Prostate Cancer in the Nordic Countries Elucidates the Timing of Improvements.
Cancers Aug, 2023 | Pubmed ID: 37627160
Early mortality critically impedes improvements in thyroid cancer survival through a half century.
European journal of endocrinology Sep, 2023 | Pubmed ID: 37675794
Steady survival improvements in soft tissue and bone sarcoma in the Nordic countries through 50 years.
Cancer epidemiology Sep, 2023 | Pubmed ID: 37679266
Long-Term Periodic and Conditional Survival Trends in Prostate, Testicular, and Penile Cancers in the Nordic Countries, Marking Timing of Improvements.
Cancers Aug, 2023 | Pubmed ID: 37686536
Identification of novel genetic loci for risk of multiple myeloma by functional annotation.
Leukemia Nov, 2023 | Pubmed ID: 37723249
miRNA and lncRNA as potential tissue biomarkers in hepatocellular carcinoma.
Non-coding RNA research Mar, 2024 | Pubmed ID: 38075204
Survival in oral and pharyngeal cancers is catching up with laryngeal cancer in the NORDIC countries through a half century.
Cancer medicine Jan, 2024 | Pubmed ID: 38164108
Prognostic role of macrophages and mast cells in the microenvironment of hepatocellular carcinoma after resection.
BMC cancer Jan, 2024 | Pubmed ID: 38287290
Genetic And Environmental Associations Of Nonspecific Chromosomal Aberrations.
Mutagenesis Feb, 2024 | Pubmed ID: 38422374
Major improvement in thyroid cancer survival of elderly patients in the Nordic countries.
European journal of endocrinology Mar, 2024 | Pubmed ID: 38436478
Large differencies in age-specific survival in multiple myeloma in the nordic countries.
Blood cancer journal Mar, 2024 | Pubmed ID: 38467614
Age-specific survival in acute myeloid leukemia in the Nordic countries through a half century.
Blood cancer journal Mar, 2024 | Pubmed ID: 38480693
Critical survival periods in prostate cancer in Sweden explored by conditional survival analysis.
Cancer medicine Apr, 2024 | Pubmed ID: 38545829
Esraa Ali1,
Lenka Červenková2,3,
Richard Pálek2,4,
Filip Ambrozkiewicz1,
Sergii Pavlov1,
Wenjing Ye1,
Petr Hošek2,
Ondrej Daum5,6,
Václav Liška2,4,
Kari Hemminki1,7,
Andriy Trailin1
1Laboratory of Translational Cancer Genomics, Biomedical Center, Faculty of Medicine in Pilsen, Charles University,
2Laboratory of Cancer Treatment and Tissue Regeneration, Biomedical Center, Faculty of Medicine in Pilsen, Charles University,
3Department of Pathology, Third Faculty of Medicine, Charles University,
4Department of Surgery and Biomedical Center, Faculty of Medicine in Pilsen, Charles University,
5Sikl's Institute of Pathology, Faculty of Medicine and Teaching Hospital in Pilsen, Charles University,
6, Bioptická Laboratoř s.r.o.,
7Department of Cancer Epidemiology, German Cancer Research Center