Thymus Biology Section,
Experimental Immunology Branch,
Center for Cancer Research,
National Cancer Institute,
Thymus Biology Section, Experimental Immunology Branch, Center for Cancer Research, National Cancer Institute
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Defective brain development in mice lacking the Hif-1alpha gene in neural cells.
Molecular and cellular biology Oct, 2003 | Pubmed ID: 12972594
Role of hypoxia-inducible factor 1alpha in T cells as a negative regulator in development of vascular remodeling.
Arteriosclerosis, thrombosis, and vascular biology Feb, 2010 | Pubmed ID: 20007912
TRAF3 enforces the requirement for T cell cross-talk in thymic medullary epithelial development.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2013 | Pubmed ID: 24324158
Thymic medullary epithelium and thymocyte self-tolerance require cooperation between CD28-CD80/86 and CD40-CD40L costimulatory pathways.
Journal of immunology (Baltimore, Md. : 1950) Jan, 2014 | Pubmed ID: 24337745
TCR affinity for thymoproteasome-dependent positively selecting peptides conditions antigen responsiveness in CD8(+) T cells.
Nature immunology Oct, 2015 | Pubmed ID: 26301566
The immunoproteasome and thymoproteasome: functions, evolution and human disease.
Nature immunology Sep, 2018 | Pubmed ID: 30104634
Thymoproteasome and peptidic self.
Immunogenetics Mar, 2019 | Pubmed ID: 30324237
A Distinct Subset of Fibroblastic Stromal Cells Constitutes the Cortex-Medulla Boundary Subcompartment of the Lymph Node.
Frontiers in immunology , 2018 | Pubmed ID: 30333825
Thymus machinery for T-cell selection.
International immunology Mar, 2019 | Pubmed ID: 30476234
Biology, evolution, and history of antigen processing and presentation: Immunogenetics special issue 2019.
Immunogenetics Mar, 2019 | Pubmed ID: 30706092
TCR Affinity for In Vivo Peptide-Induced Thymic Positive Selection Fine-Tunes TCR Responsiveness of Peripheral CD8 T Cells.
Journal of immunology (Baltimore, Md. : 1950) Aug, 2019 | Pubmed ID: 31235550
Identification of an Intronic Regulatory Element Necessary for Tissue-Specific Expression of in Thymic Epithelial Cells.
Journal of immunology (Baltimore, Md. : 1950) Aug, 2019 | Pubmed ID: 31243087
Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition).
European journal of immunology Oct, 2019 | Pubmed ID: 31633216
Trans-omics Impact of Thymoproteasome in Cortical Thymic Epithelial Cells.
Cell reports Nov, 2019 | Pubmed ID: 31775054
Myc controls a distinct transcriptional program in fetal thymic epithelial cells that determines thymus growth.
Nature communications Dec, 2019 | Pubmed ID: 31792212
PITHD1 is a proteasome-interacting protein essential for male fertilization.
The Journal of biological chemistry Feb, 2020 | Pubmed ID: 31915251
Diversity in medullary thymic epithelial cells controls the activity and availability of iNKT cells.
Nature communications May, 2020 | Pubmed ID: 32366944
Postnatal Involution and Counter-Involution of the Thymus.
Frontiers in immunology , 2020 | Pubmed ID: 32477366
Epigenetic Protection of Vertebrate Lymphoid Progenitor Cells by Dnmt1.
iScience Jul, 2020 | Pubmed ID: 32585597
The thymoproteasome hardwires the TCR repertoire of CD8+ T cells in the cortex independent of negative selection.
The Journal of experimental medicine Apr, 2021 | Pubmed ID: 33555295
Medullary stromal cells synergize their production and capture of CCL21 for T-cell emigration from neonatal mouse thymus.
Blood advances Jan, 2021 | Pubmed ID: 33570638
Thymoproteasome optimizes positive selection of CD8 T cells without contribution of negative selection.
Advances in immunology , 2021 | Pubmed ID: 33993918
Specific impact of β5t on proteasome subunit composition in cortical thymic epithelial cells.
Cell reports Sep, 2021 | Pubmed ID: 34496235
Peptides for T cell selection in the thymus.
Peptides Dec, 2021 | Pubmed ID: 34624431
mTEC damage risks immune recovery.
The Journal of experimental medicine Feb, 2022 | Pubmed ID: 34919145
Fine-tuning of β-catenin in mouse thymic epithelial cells is required for postnatal T-cell development.
eLife Jan, 2022 | Pubmed ID: 35042581
Recycling of memory B cells between germinal center and lymph node subcapsular sinus supports affinity maturation to antigenic drift.
Nature communications May, 2022 | Pubmed ID: 35513371
Tissue-specific proteasomes in generation of MHC class I peptides and CD8 T cells.
Current opinion in immunology Aug, 2022 | Pubmed ID: 35689940
Large-Scale Isolation of Mouse Thymic Epithelial Cells.
Methods in molecular biology (Clifton, N.J.) , 2023 | Pubmed ID: 36374458
The thymoproteasome in shaping the CD8 T-cell repertoire.
Current opinion in immunology Aug, 2023 | Pubmed ID: 37210932
Endogenous CCL21-Ser deficiency reduces B16-F10 melanoma growth by enhanced antitumor immunity.
Heliyon Aug, 2023 | Pubmed ID: 37664721
Developmental conversion of thymocyte-attracting cells into self-antigen-displaying cells in embryonic thymus medulla epithelium.
bioRxiv : the preprint server for biology Dec, 2023 | Pubmed ID: 37873155
Developmental conversion of thymocyte-attracting cells into self-antigen-displaying cells in embryonic thymus medulla epithelium.
eLife Mar, 2024 | Pubmed ID: 38466627
Functionally diverse thymic medullary epithelial cells interplay to direct central tolerance.
Cell reports Apr, 2024 | Pubmed ID: 38581680
Generation and repair of thymic epithelial cells.
The Journal of experimental medicine Oct, 2024 | Pubmed ID: 38980292