Department of Respiratory Medicine,
Center for Pathogen Biology and Infectious Diseases,
Department of Respiratory Medicine, Center for Pathogen Biology and Infectious Diseases
Yuguo Song is a clinical doctor and professor specialized in Occupational Medicine & Clinical Toxicology. He works as a chief-physician and an associate director at the Department of Occupational Medicine & Clinical Toxicology, Beijing Chaoyang Hospital, Capital Medical University (Beijing, China). He received his B.S degree in clinical medicine from the University of Tsingdao Medical College, Shandong Province in 1990, and then he got his MD and Ph.D degree in Capital Medical University. He is the recipient of several research achievement awards including Wu Zhizhong Prize in occupational medicine (China) and International Travel Award from the American Academy of Clinical Toxicology. He ever worked as a visiting scholar in 2010 at West Virginia University, USA. His research focus is clinical toxicology, nanotoxicology, metal toxicology and occupational lung diseases.
1. Cao W, Zhou Y, Niu Y, Zhu X, Song Y, Guo R. Quantitative analysis of hepatic toxicity in rats induced by inhalable silica nanoparticles using acoustic radiation force imaging. J Ultrasound Med. 2017,36(9) :1829-1839.
2. Zhu X, Cao W, Chang B, Zhang L, Qiao P, Li X, Si L, Niu Y, Song Y . Polyacrylate/nanosilica causes pleural and pericardial effusion, and pulmonary fibrosis and granuloma in rats similar to those observed in exposed workers. Int J Nanomedicine 2016;11:1593-605.
3.Niu YM, Zhu XL, Chang B, Tong ZH, Cao W, Qiao PH, Zhang LY, Zhao J, Song YG. Nanosilica and polyacrylate/nanosilica: a comparative study of acute toxicity. Biomed Res Int. 2016. 2016: 9353275.
4. Song Y, Li X, Wang L, Rojanasakul Y, Castranova V, Li H, Ma J. Nanomaterials in humans: identification, characteristics, and potential damage. Toxicol Pathol. 2011;39(5):841-849.
5. Song Y, Tang S. Nanoexposure, unusual diseases, and new health and safety concerns. TheScientificWorldJOURNAL. 2011, 11: 1821–1828.
6. Song Y, Du X, Hao F, Gu X, Zhang Z, Zhang S, Li C, Li H, Ma J. Immunosuppressive therapy of cyclosporin A for severe benzene-induced haematopoietic disorders and a 6-month follow-up. Chem Biol Interact. 2010;186(1):96-102.
7. Song Y, Li X, Du X. Exposure to nanoparticles is related to pleural effusion, pulmonary fibrosis and granuloma. Eur Respir J. 2009; 34(3):559-567.
rAAV/ABAD-DP-6His attenuates oxidative stress-induced injury of PC12 cells.
Neural regeneration research Mar, 2014 | Pubmed ID: 25206842
piR-55490 inhibits the growth of lung carcinoma by suppressing mTOR signaling.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine Feb, 2016 | Pubmed ID: 26408181
Upregulation of microRNA-31 targeting integrin α5 suppresses tumor cell invasion and metastasis by indirectly regulating PI3K/AKT pathway in human gastric cancer SGC7901 cells.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine Jun, 2016 | Pubmed ID: 26729197
Let-7a modulates particulate matter (≤ 2.5 μm)-induced oxidative stress and injury in human airway epithelial cells by targeting arginase 2.
Journal of applied toxicology : JAT Oct, 2016 | Pubmed ID: 26989813
Strong evidence for LncRNA ZNRD1-AS1, and its functional Cis- eQTL locus contributing more to the susceptibility of lung cancer.
Oncotarget Jun, 2016 | Pubmed ID: 27166266
MicroRNA-21 promotes TGF-β1-induced epithelial-mesenchymal transition in gastric cancer through up-regulating PTEN expression.
Oncotarget Oct, 2016 | Pubmed ID: 27611950
Relationships of MMP-9 and TIMP-1 proteins with chronic obstructive pulmonary disease risk: A systematic review and meta-analysis.
Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences , 2016 | Pubmed ID: 27904558
Inhibition of Beclin-1-Mediated Autophagy by MicroRNA-17-5p Enhanced the Radiosensitivity of Glioma Cells.
Oncology research Jan, 2017 | Pubmed ID: 28081732
Exposure to PM2.5 induces aberrant activation of NF-κB in human airway epithelial cells by downregulating miR-331 expression.
Environmental toxicology and pharmacology Mar, 2017 | Pubmed ID: 28192748
miR-155 Inhibits Mouse Osteoblast Differentiation by Suppressing SMAD5 Expression.
BioMed research international , 2017 | Pubmed ID: 28473977
WITHAFERIN A INDUCES APOPTOSIS IN RAT C6 GLIOMA CELLS THROUGH REGULATING NF-KB NUCLEAR TRANSLOCATION AND ACTIVATION OF CASPASE CASCADE.
African journal of traditional, complementary, and alternative medicines : AJTCAM , 2017 | Pubmed ID: 28573248
Inhibition of MicroRNA-21-5p Promotes the Radiation Sensitivity of Non-Small Cell Lung Cancer Through HMSH2.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology , 2017 | Pubmed ID: 29024929
6'--Galloylpaeoniflorin Attenuates Cerebral Ischemia Reperfusion-Induced Neuroinflammation and Oxidative Stress via PI3K/Akt/Nrf2 Activation.
Oxidative medicine and cellular longevity , 2018 | Pubmed ID: 29765506
miR-144-5p Enhances the Radiosensitivity of Non-Small-Cell Lung Cancer Cells via Targeting ATF2.
BioMed research international , 2018 | Pubmed ID: 29850528
Post-translational regulation of ubiquitin signaling.
The Journal of cell biology Jun, 2019 | Pubmed ID: 31000580
Correction: MicroRNA-21 promotes TGF-β1-induced epithelial-mesenchymal transition in gastric cancer through up-regulating PTEN expression.
Oncotarget Aug, 2020 | Pubmed ID: 32922665
Novel drug delivery systems targeting oxidative stress in chronic obstructive pulmonary disease: a review.
Journal of nanobiotechnology Oct, 2020 | Pubmed ID: 33076918
Ophiopogonin D attenuates PM2.5-induced inflammation via suppressing the AMPK/NF-κB pathway in mouse pulmonary epithelial cells.
Experimental and therapeutic medicine Dec, 2020 | Pubmed ID: 33093877
Epidemiological and clinical characteristics of 2019 novel coronavirus disease (COVID-19) in Jilin, China: A descriptive study.
Medicine Nov, 2020 | Pubmed ID: 33217886
Association Between Clinical Characteristics and Short-Term Outcomes in Adult Male COVID-19 Patients With Mild Clinical Symptoms: A Single-Center Observational Study.
Frontiers in medicine , 2020 | Pubmed ID: 33469542
Perspectives and controversies regarding the use of natural products for the treatment of lung cancer.
Cancer medicine Apr, 2021 | Pubmed ID: 33650320
The protective role of Zingerone in a murine asthma model via activation of the AMPK/Nrf2/HO-1 pathway.
Food & function Apr, 2021 | Pubmed ID: 33725040
Case Report: Histiocytic Necrotizing Lymphadenitis (Kikuchi-Fujimoto Disease) Concurrent With Aseptic Meningitis.
Frontiers in neurology , 2021 | Pubmed ID: 33959084
Calycosin Alleviates Injury in Airway Epithelial Cells Caused by PM 2.5 Exposure via Activation of AMPK Signalling.
Evidence-based complementary and alternative medicine : eCAM , 2021 | Pubmed ID: 34055025
Novel Role of miR-18a-5p and Galanin in Rat Lung Ischemia Reperfusion-Mediated Response.
Oxidative medicine and cellular longevity , 2021 | Pubmed ID: 34497682
The Herbal Compound Thymol Targets Multiple Typhimurium Virulence Factors for Lon Protease Degradation.
Frontiers in pharmacology , 2021 | Pubmed ID: 34512322
Bixin protects mice against bronchial asthma though modulating PI3K/Akt pathway.
International immunopharmacology Dec, 2021 | Pubmed ID: 34678694
inhibits host immunity by a protein phosphatase adapted from glycolysis.
Proceedings of the National Academy of Sciences of the United States of America , | Pubmed ID: 34930823
Exploitation of the Host Ubiquitin System: Means by .
Frontiers in microbiology , | Pubmed ID: 35003021
modulates host energy metabolism by ADP-ribosylation of ADP/ATP translocases.
eLife , | Pubmed ID: 35084332
The dual roles of autophagy and the GPCRs-mediating autophagy signaling pathway after cerebral ischemic stroke.
Molecular brain , | Pubmed ID: 35109896
regulates host cell motility by targeting Phldb2 with a 14-3-3ζ-dependent protease effector.
eLife , | Pubmed ID: 35175192
Maackiain protects against sepsis via activating AMPK/Nrf2/HO-1 pathway.
International immunopharmacology , | Pubmed ID: 35405595
PM2.5 Exposure and Asthma Development: The Key Role of Oxidative Stress.
Oxidative medicine and cellular longevity , | Pubmed ID: 35419163
The Correlation of PM2.5 Exposure with Acute Attack and Steroid Sensitivity in Asthma.
BioMed research international , | Pubmed ID: 36033576
Efficacy of terpenoids in attenuating pulmonary edema in acute lung injury: A meta-analysis of animal studies.
Frontiers in pharmacology , | Pubmed ID: 36034851
A natural compound hyperoside targets Typhimurium T3SS needle protein InvG.
Food & function , | Pubmed ID: 36124641
Subversion of host cell signaling: The arsenal of Rickettsial species.
Frontiers in cellular and infection microbiology , 2022 | Pubmed ID: 36389139
Anwuligan inhibits the progression of non-small cell lung cancer via let-7c-3p/PI3K/AKT/mTOR axis.
Cancer medicine Mar, 2023 | Pubmed ID: 36412203
Acinetobacter baumannii Kills Fungi via a Type VI DNase Effector.
mBio Feb, 2023 | Pubmed ID: 36625573
Characteristics of the Severe Acute Respiratory Syndrome Coronavirus 2 Omicron BA.2 Subvariant in Jilin, China from March to May 2022.
Journal of translational internal medicine Dec, 2022 | Pubmed ID: 36860638
Immune checkpoint inhibitors related respiratory disorders in patients with lung cancer: A meta-analysis of randomized controlled trials.
Frontiers in immunology , 2023 | Pubmed ID: 36926326
Au/Mn nanodot platform for CT/MRI/FI multimodal bioimaging and photothermal therapy against tongue cancer.
Journal of materials chemistry. B May, 2023 | Pubmed ID: 37183453
The versatile defender: exploring the multifaceted role of p62 in intracellular bacterial infection.
Frontiers in cellular and infection microbiology , 2023 | Pubmed ID: 37216179
Editorial: Phytochemicals targeting autophagy in treatment of bacterial infection and malignancies.
Frontiers in pharmacology , 2023 | Pubmed ID: 37256228
Ferroptosis in pulmonary fibrosis: an emerging therapeutic target.
Frontiers in physiology , 2023 | Pubmed ID: 37664432
Activation of PI3K/Akt pathway by G protein-coupled receptor 37 promotes resistance to cisplatin-induced apoptosis in non-small cell lung cancer.
Cancer medicine Oct, 2023 | Pubmed ID: 37732632
The intricate dance: host autophagy and infection.
Frontiers in microbiology , 2023 | Pubmed ID: 37808314
"All in one" nanoprobe Au-TTF-1 for target FL/CT bioimaging, machine learning technology and imaging-guided photothermal therapy against lung adenocarcinoma.
Journal of nanobiotechnology Jan, 2024 | Pubmed ID: 38184620
Novel nanoparticle AuNCs conjugated with Desmoglein-3 antibody for FL/CT dual-mode targeted imaging and precise treatment of lung squamous cell carcinoma.
Journal of colloid and interface science Apr, 2024 | Pubmed ID: 38224630
Unveiling the Intricacies of Autophagy in Asthma: Unraveling Novel Therapeutic Avenues.
Frontiers in bioscience (Landmark edition) Jan, 2024 | Pubmed ID: 38287830
Editorial: Innate immunity against intracellular bacteria: mechanisms and strategies.
Frontiers in immunology , 2024 | Pubmed ID: 38571948
Trim27 aggravates airway inflammation and oxidative stress in asthmatic mice via potentiating the NLRP3 inflammasome.
International immunopharmacology Jun, 2024 | Pubmed ID: 38713938
temporally regulates the activity of ADP/ATP translocases by reversible ADP-ribosylation.
mLife Mar, 2022 | Pubmed ID: 38818321
Legionella maintains host cell ubiquitin homeostasis by effectors with unique catalytic mechanisms.
Research square May, 2024 | Pubmed ID: 38826349
utilizes a unique type VI secretion system to promote its survival in niches with prey bacteria.
mBio Jul, 2024 | Pubmed ID: 38916378
Legionella maintains host cell ubiquitin homeostasis by effectors with unique catalytic mechanisms.
Nature communications Jul, 2024 | Pubmed ID: 39009586
Corrigendum to "Maackiain protects against sepsis via activating AMPK/Nrf2/HO-1 pathway" [Int. Immunopharmacol. 108 (2022) 108710].
International immunopharmacology Oct, 2024 | Pubmed ID: 39127491
Insights into the role of legionella effectors on host metabolic perturbations.
Frontiers in cellular and infection microbiology , 2024 | Pubmed ID: 39324059
A unique cell division protein critical for the assembly of the bacterial divisome.
eLife Oct, 2024 | Pubmed ID: 39361022
Comprehensive pan-genome analysis of Mycobacterium marinum: insights into genomic diversity, evolution, and pathogenicity.
Scientific reports Nov, 2024 | Pubmed ID: 39532890
Nanozyme as Tumor Energy Homeostasis Disruptor to Augment Cascade Catalytic Therapy.
ACS nano Dec, 2024 | Pubmed ID: 39661982
Isoferulic acid facilitates effective clearance of hypervirulent Klebsiella pneumoniae through targeting capsule.
PLoS pathogens Jan, 2025 | Pubmed ID: 39761301
In silico characterization of defense system hotspots in Acinetobacter spp.
Communications biology Jan, 2025 | Pubmed ID: 39794449