Holden T. Maecker

Dynamics of CD4 and CD8 T cell responses to cytomegalovirus in healthy human donors.

Epigenetic changes in tumor Fas levels determine immune escape and response to therapy.

Increased brain size and glial cell number in CD81-null mice.

Human CD81 directly enhances Th1 and Th2 cell activation, but preferentially induces proliferation of Th2 cells upon long-term stimulation.

Analysis of the frequencies and of the memory T cell phenotypes of human CD8+ T cells specific for influenza A viruses.

Optimal preparation of rhesus macaque blood for cytokine flow cytometric analysis.

Performance of plate-based cytokine flow cytometry with automated data analysis.

TNF-alpha detection using a flow cytometric assay to determine cellular responses to anthrax vaccine.

Strong cell-mediated immune responses are associated with the maintenance of low-level viremia in antiretroviral-treated individuals with drug-resistant human immunodeficiency virus type 1.

Cytokine flow cytometry.

Persistent and selective deficiency of CD4+ T cell immunity to cytomegalovirus in immunocompetent young children.

T cell immunity to HIV: defining parameters of protection.

Cytokine flow cytometry: a multiparametric approach for assessing cellular immune responses to viral antigens.

Results of a cytomegalovirus (CMV)-specific CD8+/interferon- gamma+ cytokine flow cytometry assay correlate with clinical evidence of protective immunity in patients with AIDS with CMV retinitis.

Analyzing T-cell responses to cytomegalovirus by cytokine flow cytometry.

Selecting fluorochrome conjugates for maximum sensitivity.

Multicolor flow cytometric analysis in SIV-infected rhesus macaque.

Dysfunction of simian immunodeficiency virus/simian human immunodeficiency virus-induced IL-2 expression by central memory CD4+ T lymphocytes.

Immune dysfunction and micrometastases in women with breast cancer.

Ex vivo analysis of T-cell function.

Standardization of cytokine flow cytometry assays.

Impact of cryopreservation on tetramer, cytokine flow cytometry, and ELISPOT.

Maximizing the retention of antigen specific lymphocyte function after cryopreservation.

Immune responses in the draining lymph nodes against cancer: implications for immunotherapy.

IL-2 production correlates with effector cell differentiation in HIV-specific CD8+ T cells.

Flow cytometry controls, instrument setup, and the determination of positivity.

Protective immunity to cytomegalovirus (CMV) retinitis in AIDS is associated with CMV-specific T cells that express interferon- gamma and interleukin-2 and have a CD8+ cell early maturational phenotype.

Phenotype and in vitro function of mature MDDC generated from cryopreserved PBMC of cancer patients are equivalent to those from healthy donors.

Functional T cell responses to tumor antigens in breast cancer patients have a distinct phenotype and cytokine signature.

Results and harmonization guidelines from two large-scale international Elispot proficiency panels conducted by the Cancer Vaccine Consortium (CVC/SVI).

An analytical workflow for investigating cytokine profiles.

Poor predictive value of cytomegalovirus (CMV)-specific T cell assays for the development of CMV retinitis in patients with AIDS.

Development and dynamics of robust T-cell responses to CML under imatinib treatment.

Precision and linearity targets for validation of an IFNgamma ELISPOT, cytokine flow cytometry, and tetramer assay using CMV peptides.

Standardization and optimization of multiparameter intracellular cytokine staining.

Multiparameter flow cytometry monitoring of T cell responses.

"MIATA"-minimal information about T cell assays.

New technologies for autoimmune disease monitoring.

Quality assurance of intracellular cytokine staining assays: analysis of multiple rounds of proficiency testing.

A model for harmonizing flow cytometry in clinical trials.

Multiparameter intracellular cytokine staining.

Recommendations from the iSBTc-SITC/FDA/NCI Workshop on Immunotherapy Biomarkers.

Standardizing immunophenotyping for the Human Immunology Project.

The Stanford Data Miner: a novel approach for integrating and exploring heterogeneous immunological data.

New tools for classification and monitoring of autoimmune diseases.