Jiayu Liao

Comparative analysis of human genome assemblies reveals genome-level differences.

Three sweet receptor genes are clustered in human chromosome 1.

Sphingosine 1-phosphate pathway therapeutics: a lipid ligand-receptor paradigm.

A comparative analysis of HGSC and Celera human genome assemblies and gene sets.

Sphingosine 1-phosphate (S1P) receptor subtypes S1P1 and S1P3, respectively, regulate lymphocyte recirculation and heart rate.

A nonpeptidic agonist of glucagon-like peptide 1 receptors with efficacy in diabetic db/db mice.

Protein and cellular engineering with unnatural amino acids.

Boc5, a non-peptidic glucagon-like Peptide-1 receptor agonist, invokes sustained glycemic control and weight loss in diabetic mice.

mTOR supports long-term self-renewal and suppresses mesoderm and endoderm activities of human embryonic stem cells.

Reversal of obesity and insulin resistance by a non-peptidic glucagon-like peptide-1 receptor agonist in diet-induced obese mice.

Development of FRET assay into quantitative and high-throughput screening technology platforms for protein-protein interactions.

Feasible Synthesis of Antagonist of GPR40 by Constructing 2-Thiouracil Ring viaAcid Mediated Cyclization.

Chemoselective fabrication of high density peptide microarray by hetero-bifunctional tetra(ethylene glycol) linker for click chemistry conjugation.

Cyclobutane derivatives as novel nonpeptidic small molecule agonists of glucagon-like peptide-1 receptor.

An in vitro Förster resonance energy transfer-based high-throughput screening assay for inhibitors of protein-protein interactions in SUMOylation pathway.

A fluorescent amino acid probe to monitor efficiency of peptide conjugation to glass surfaces for high density microarrays.

Quantitative Förster resonance energy transfer analysis for kinetic determinations of SUMO-specific protease.

Systematic determinations of SUMOylation activation intermediates and dynamics by a sensitive and quantitative FRET assay.

Protein interaction affinity determination by quantitative FRET technology.

Anaplasma phagocytophilum dihydrolipoamide dehydrogenase 1 affects host-derived immunopathology during microbial colonization.