Orly Reiner

Alternative splice variants of doublecortin-like kinase are differentially expressed and have different kinase activities.

LIS1, CLIP-170's key to the dynein/dynactin pathway.

Pathways of neuronal migration.

LIS1 missense mutations: variable phenotypes result from unpredictable alterations in biochemical and cellular properties.

DCX, a new mediator of the JNK pathway.

DCX's phosphorylation by not just another kinase (JNK).

The structure of the N-terminal domain of the product of the lissencephaly gene Lis1 and its functional implications.

HIV-1 Tat interacts with LIS1 protein.

Binding of microtubule-associated protein 1B to LIS1 affects the interaction between dynein and LIS1.

Similarities and differences between the Wnt and reelin pathways in the forming brain.

Novel functional features of the Lis-H domain: role in protein dimerization, half-life and cellular localization.

Doublecortin-like kinase controls neurogenesis by regulating mitotic spindles and M phase progression.

Cdk5 checks p27kip1 in neuronal migration.

Site-specific dephosphorylation of doublecortin (DCX) by protein phosphatase 1 (PP1).

Common and divergent roles for members of the mouse DCX superfamily.

The evolving doublecortin (DCX) superfamily.

Lissencephaly 1 linking to multiple diseases: mental retardation, neurodegeneration, schizophrenia, male sterility, and more.

Postnatal alterations of the inhibitory synaptic responses recorded from cortical pyramidal neurons in the Lis1/sLis1 mutant mouse.

Migration cues induce chromatin alterations.

Doublecortin supports the development of dendritic arbors in primary hippocampal neurons.

Accurate balance of the polarity kinase MARK2/Par-1 is required for proper cortical neuronal migration.

Gene trapping: an antibody-dependent approach for verifying integration in your favorite gene.

Antagonistic effects of doublecortin and MARK2/Par-1 in the developing cerebral cortex.

Increased LIS1 expression affects human and mouse brain development.

Polarity regulation in migrating neurons in the cortex.

Neuronal migration and neurodegeneration: 2 sides of the same coin.

Ndel1 palmitoylation: a new mean to regulate cytoplasmic dynein activity.

PAF-AH Catalytic Subunits Modulate the Wnt Pathway in Developing GABAergic Neurons.

A JIP3-regulated GSK3β/DCX signaling pathway restricts axon branching.

Interkinetic nuclear movement in the ventricular zone of the cortex.

MARK2/Par-1 guides the directionality of neuroblasts migrating to the olfactory bulb.

Stress-activated protein kinase MKK7 regulates axon elongation in the developing cerebral cortex.

Linking cytoplasmic dynein and transport of Rab8 vesicles to the midbody during cytokinesis by the doublecortin domain-containing 5 protein.

Tau's role in the developing brain: implications for intellectual disability.

Microtubule dynamics alter the interphase nucleus.

Ndel1-derived peptides modulate bidirectional transport of injected beads in the squid giant axon.

Loss of PAFAH1B2 reduces amyloid-β generation by promoting the degradation of amyloid precursor protein C-terminal fragments.

Shootin1 acts in concert with KIF20B to promote polarization of migrating neurons.

LIS1 functions in normal development and disease.