Timothy D. Bigby

The yin and the yang of 5-lipoxygenase pathway activation.

What about the role of the US Food and Drug Administration?

5-lipoxygenase-activating protein gene expression. Key role of CCAAT/enhancer-binding proteins (C/EBP) in constitutive and tumor necrosis factor (TNF) alpha-induced expression in THP-1 cells.

Lipopolysaccharide down-regulates the leukotriene C4 synthase gene in the monocyte-like cell line, THP-1.

Lipopolysaccharide down-regulates leukotriene C4 synthase gene expression in a cell-specific manner in the monocyte-like cell line, THP-1.

Regulation of leukotriene C4 synthase gene expression by SP1 and SP3 in mononuclear phagocytes.

Mechanisms of glomerular immune injury: effects of antioxidant treatment.

Allergen-independent immunostimulatory sequence oligodeoxynucleotide therapy attenuates experimental allergic rhinitis.

Lipopolysaccharide induces 5-lipoxygenase-activating protein gene expression in THP-1 cells via a NF-kappaB and C/EBP-mediated mechanism.

The cobalamin precursor cobinamide detoxifies nitroprusside-generated cyanide.

Nitrosyl-cobinamide, a new and direct nitric oxide releasing drug effective in vivo.

Cyanide produced by human isolates of Pseudomonas aeruginosa contributes to lethality in Drosophila melanogaster.

Innate immunity and asthma.

Cobinamide is superior to other treatments in a mouse model of cyanide poisoning.

The combination of cobinamide and sulfanegen is highly effective in mouse models of cyanide poisoning.