Kyle Denton

Identification of novel genetic markers associated with clinical phenotypes of systemic sclerosis through a genome-wide association strategy.

Retinoic acid receptor signaling regulates choroid fissure closure through independent mechanisms in the ventral optic cup and periocular mesenchyme.

Primary care of adults with developmental disabilities: Canadian consensus guidelines.

Association of a non-synonymous functional variant of the ITGAM gene with systemic sclerosis.

Recent advances in the diagnosis and treatment of interstitial lung disease in systemic sclerosis (scleroderma): a review.

One percent tenofovir applied topically to humanized BLT mice and used according to the CAPRISA 004 experimental design demonstrates partial protection from vaginal HIV infection, validating the BLT model for evaluation of new microbicide candidates.

Impact of a medical waste incinerator on mercury levels in lagoon fish from a small tropical island in the Western Pacific.

Identifying research priorities in long term care homes.

The Relations Among Oral and Silent Reading Fluency and Comprehension in Middle School: Implications for Identification and Instruction of Students With Reading Difficulties.

Loss of PTEN expression by dermal fibroblasts causes skin fibrosis.

Thoracic outlet syndrome: a controversial clinical condition. Part 1: anatomy, and clinical examination/diagnosis.

Cortical activation and lamina terminalis functional connectivity during thirst and drinking in humans.

Systemic sclerosis-associated pulmonary hypertension: why disease-specific composite endpoints are needed.

Crowding of polymer coils and demixing in nanoparticle-polymer mixtures.

Social determinants of older adults' awareness of community support services in Hamilton, Ontario.

Catalytic phosphorus(V)-mediated nucleophilic substitution reactions: development of a catalytic Appel reaction.

Relation of addiction genes to hypothalamic gene changes subserving genesis and gratification of a classic instinct, sodium appetite.

Elevated CCN2 expression in scleroderma: a putative role for the TGFβ accessory receptors TGFβRIII and endoglin.

Improving the detection of pulmonary hypertension in systemic sclerosis using pulmonary function tests.

Sequential rhodium-, silver-, and gold-catalyzed synthesis of fused dihydrofurans.

Replies to: The danger to cytopathology of over-specialization and its relevance for histopathology.

Bilateral, geographic, peripapillary, chorioretinal atrophy in a patient with porphyria cutanea tarda and high iron stores.

An Experimental Study of Scheduling and Duration of "Tier 2" First-Grade Reading Intervention.

Humanized mouse models of HIV infection.

Biomarkers for skin involvement and fibrotic activity in scleroderma.

Clinical and serological hallmarks of systemic sclerosis overlap syndromes.

Multiple births: an update.

Toward developing a training pathway for fertility nurses: report of the 2010 training and educational survey.

Confirmation of association of the macrophage migration inhibitory factor gene with systemic sclerosis in a large European population.

Differentiation-dependent functional and epigenetic landscapes for cytokine genes in virus-specific CD8+ T cells.

Pleuroperitoneal leak complicating peritoneal dialysis: a case series.

Thoracic outlet syndrome: a controversial clinical condition. Part 2: non-surgical and surgical management.

The renin-angiotensin system: new horizons.

A rare polymorphism in the gene for Toll-like receptor 2 is associated with systemic sclerosis phenotype and increases the production of inflammatory mediators.

It is time for changes in the analysis of whole effluent toxicity data.

Urine-concentrating defects exacerbate with age in male offspring with a low-nephron endowment.

Optimization of PSA screening policies: a comparison of the patient and societal perspectives.

Analysis of the validation status of quality of life and functional disability measures in pulmonary arterial hypertension related to systemic sclerosis: results of a systematic literature analysis by the Expert Panel on Outcomes Measures in Pulmonary Arterial Hypertension related to Systemic Sclerosis (EPOSS).

The Effect of Sub-MIC β-Lactam Antibiotic Exposure of Pseudomonas aeruginosa Strains from People with Cystic Fibrosis in a Desiccation Survival Model.

Analysis of incidence and clinical outcomes in patients with thromboembolic events and invasive exocrine pancreatic cancer.

Haematopoietic SCT in severe autoimmune diseases: updated guidelines of the European Group for Blood and Marrow Transplantation.

The autoimmune disease-associated IL2RA locus is involved in the clinical manifestations of systemic sclerosis.

Generation of HIV latency in humanized BLT mice.

Characterization of D-glucaric acid using NMR, X-ray crystal structure, and MM3 molecular modeling analyses.

Costs of medical care after open or minimally invasive prostate cancer surgery: a population-based analysis.

Effects of hydrated lime and quicklime on the decay of buried human remains using pig cadavers as human body analogues.

The arterial depressor response to chronic low-dose angiotensin II infusion in female rats is estrogen dependent.

Reproductive health in Irish female renal transplant recipients.

Affinity thresholds for naive CD8+ CTL activation by peptides and engineered influenza A viruses.

Cell death by autophagy: facts and apparent artefacts.

Items for developing revised classification criteria in systemic sclerosis: Results of a consensus exercise with the ACR/EULAR working committee for classification criteria in systemic sclerosis.

Income replacement in retirement: longitudinal evidence from income tax records.

Age of pension eligibility, gains in life expectancy, and social policy.

Disruption of Trichoderma reesei cre2, encoding an ubiquitin C-terminal hydrolase, results in increased cellulase activity.

In the arms of Morpheus.

Cell biology. Pyro-technic control of metabolism.

A GWAS follow-up study reveals the association of the IL12RB2 gene with systemic sclerosis in Caucasian populations.

Fecal incontinence in systemic sclerosis is secondary to neuropathy.

The discovery of UK-369003, a novel PDE5 inhibitor with the potential for oral bioavailability and dose-proportional pharmacokinetics.

PmrB mutations promote polymyxin resistance of Pseudomonas aeruginosa isolated from colistin-treated cystic fibrosis patients.

A resource for the in silico identification of fungal polyketide synthases from predicted fungal proteomes.

Sex differences in the pressor and tubuloglomerular feedback response to angiotensin II.

Risk factors associated with pulmonary arterial hypertension in patients with systemic sclerosis and implications for screening.

Channeling dysglycemia: ion-channel variations perturbing glucose homeostasis.

Good ethical tone in the work setting.

Development and evaluation of an ovine antibody-based platform for treatment of Clostridium difficile infection.

Sex-specific influence of angiotensin type 2 receptor stimulation on renal function: a novel therapeutic target for hypertension.

Deficits in the mitochondrial enzyme α-ketoglutarate dehydrogenase lead to Alzheimer's disease-like calcium dysregulation.

Systems analysis of a maize leaf developmental gradient redefines the current C4 model and provides candidates for regulation.

Differential mechanisms of ang (1-7)-mediated vasodepressor effect in adult and aged candesartan-treated rats.

Headache after substance abuse: a diagnostic dilemma.

Demographic, clinical and antibody characteristics of patients with digital ulcers in systemic sclerosis: data from the DUO Registry.

Haemopoietic stem-cell transplantation for systemic sclerosis.

Postnatal ontogeny of angiotensin receptors and ACE2 in male and female rats.

Discovery, characterization, and structure-activity relationships of an inhibitor of inward rectifier potassium (Kir) channels with preference for Kir2.3, Kir3.x, and Kir7.1.

EVALUATION OF THE TEST OF SIGNIFICANT TOXICITY FOR DETERMINING THE TOXICITY OF EFFLUENTS AND AMBIENT WATER SAMPLES.

Severe interstitial lung disease in connective tissue disease: rituximab as rescue therapy.

Predictors of creatinine rise post-endovascular abdominal aortic aneurysm repair.

Simulation optimization of PSA-threshold based prostate cancer screening policies.

Pressure and pain In Systemic sclerosis/ Scleroderma - an evaluation of a simple intervention (PISCES): randomised controlled trial protocol.

An examination of the dynamic changes in prostate-specific antigen occurring in a population-based cohort of men over time.

Renal responses to furosemide are significantly attenuated in male sheep at 6 months of age following fetal uninephrectomy.

Scientific standards and the regulation of genetically modified insects.

Patterns and predictors of change in outcome measures in clinical trials in scleroderma: an individual patient meta-analysis of 629 subjects with diffuse cutaneous systemic sclerosis.

Effects of tempol and candesartan on neural control of the kidney.

The angiotensin type 2 receptor weighs in on obesity: a promising therapeutic target?

Detecting mineral content in turbid medium using nonlinear Raman imaging: feasibility study.

Control of konzo in DRC using the wetting method on cassava flour.

An in depth analysis of histopathological characteristics found in keratoconus.

Identification of CSK as a systemic sclerosis genetic risk factor through Genome Wide Association Study follow-up.

Bloodstream infections in cystic fibrosis: nine years of experience in both adults and children.

Associations between cardiorespiratory fitness, physical activity and clustered cardiometabolic risk in children and adolescents: the HAPPY study.

A screening method for assessing cumulative impacts.

Does the authenticity of preclinical teaching format affect subsequent clinical clerkship outcomes? A prospective randomized crossover trial.

Response to intervention for reading difficulties in the primary grades: some answers and lingering questions.

Mucosal HIV-1 transmission and prevention strategies in BLT humanized mice.

Primes and flankers: source confusions and discounting.

A multicenter study confirms CD226 gene association with systemic sclerosis-related pulmonary fibrosis.

Are we mindful of psychosis?

Relationship between growth arrest and autophagy in midgut programmed cell death in Drosophila.

IL-2 receptor γ-chain molecule is critical for intestinal T-cell reconstitution in humanized mice.

Long-term alteration in maternal blood pressure and renal function after pregnancy in normal and growth-restricted rats.

Clinical and pathological significance of interleukin 6 overexpression in systemic sclerosis.

Posttraumatic stress and myocardial infarction risk perceptions in hospitalized acute coronary syndrome patients.

Effect of perioperative blood transfusions on long term graft outcomes in renal transplant patients.

Update on the profile of the EUSTAR cohort: an analysis of the EULAR Scleroderma Trials and Research group database.

Family structure, family disruption, and profiles of adolescent religiosity.

Nef functions in BLT mice to enhance HIV-1 replication and deplete CD4+CD8+ thymocytes.

Home haemodialysis in Ireland.

Silicone lymphadenopathy: an unexpected cause of neck lumps.

Relationship between clinical experiences and internal medicine clerkship performance.

Role of N-terminal pro-brain natriuretic peptide in detecting clinically significant cardiac involvement in systemic sclerosis patients.

Clinical trial design in scleroderma: where are we and where do we go next?

The Fear of Others: A Qualitative Analysis of Interpersonal Threat in Social Phobia and Paranoia.

Impact of hallmark autoantibody reactivity on early diagnosis in scleroderma.

A strategy for the synthesis of the fargenone/fargenin family of natural products: synthesis of the tricyclic core.

ChromoHub: a data hub for navigators of chromatin-mediated signalling.

Sustained improvement of diffuse systemic sclerosis following human cytomegalovirus infection offers insight into pathogenesis and therapy.

Factor H autoantibodies in membranoproliferative glomerulonephritis.

Juvenile and young adult-onset systemic sclerosis share the same organ involvement in adulthood: data from the EUSTAR database.

Human breast milk and antiretrovirals dramatically reduce oral HIV-1 transmission in BLT humanized mice.

Studies of implicit prototype extraction in patients with mild cognitive impairment and early Alzheimer's disease.

The successful development of a subacute care service associated with a large academic health system.

Anxiety and inattention as predictors of achievement in early elementary school children.

Augmenting antidepressant medication treatment of depressed women with emotionally focused therapy for couples: a randomized pilot study.

Concordance of outcomes of pairs of kidneys transplanted into different recipients.

Comparing a script concordance examination to a multiple-choice examination on a core internal medicine clerkship.

Sex differences in the renal vascular response to angiotensin II involves the Mas receptor.

Synthesis and biological evaluation of novel flavonols as potential anti-prostate cancer agents.

The use of Enhancing Quality Use of Medication Self-Reported Questionniare (EQUIM-SRQ) among mental health consumers: a pilot study.

Cloning, expression and characterization of lepidopteran isopentenyl diphosphate isomerase.

DNA repair and crossing over favor similar chromosome regions as discovered in radiation hybrid of Triticum.

Pharmacology of DB844, an orally active aza analogue of pafuramidine, in a monkey model of second stage human African trypanosomiasis.

Stable isotope gas chromatography-tandem mass spectrometry determination of aminoethylcysteine ketimine decarboxylated dimer in biological samples.

Increased cardiovascular and renal risk is associated with low nephron endowment in aged females: an ovine model of fetal unilateral nephrectomy.

Phosphate enrichment of dialysate for use in standard and extended haemodialysis.

Confirmation of TNIP1 but not RHOB and PSORS1C1 as systemic sclerosis risk factors in a large independent replication study.

Psychosocial vulnerabilities to depression after acute coronary syndrome: the pivotal role of rumination in predicting and maintaining depression.

Logical Rules and the Classification of Integral-Dimension Stimuli.

Gut fibrosis with altered colonic contractility in a mouse model of scleroderma.

Cytomegalovirus CC chemokine promotes immune cell migration.

Appropriate maternal weight gain in singleton and twin pregnancies: what is the evidence?

Efforts to identify at-risk children for blood lead screening in pediatric clinics--Clark County, Nevada.

Methicillin-resistant Staphylococcus aureus.

Twenty-year survivors of kidney transplantation.

Guidelines for the use and interpretation of assays for monitoring autophagy.

Impact of obesity on perioperative complications and long-term survival of patients with gastric cancer.

Focal adhesion kinase and reactive oxygen species contribute to the persistent fibrotic phenotype of lesional scleroderma fibroblasts.

Accelerometry-assessed sedentary behaviour and physical activity levels during the segmented school day in 10-14-year-old children: the HAPPY study.

Scaffold-hopping with zwitterionic CCR3 antagonists: identification and optimisation of a series with good potency and pharmacokinetics leading to the discovery of AZ12436092.

Influence of the IL6 gene in susceptibility to systemic sclerosis.

Infected calcinosis of the knee in limited cutaneous systemic sclerosis.

Membrane-based oligonucleotide array developed from multiple markers for the detection of many phytophthora species.

Treating chemotherapy induced agranulocytosis with granulocyte colony-stimulating factors in a patient on clozapine.

Glomerular disease recurrence in second and subsequent kidney transplants.

Blunted sodium excretion in response to a saline load in 5 year old female sheep following fetal uninephrectomy.

Discovery and evolution of phenoxypiperidine hydroxyamide dual CCR3/H₁ antagonists. Part II: optimising in vivo clearance.

Epidemiology and Management of Depression Following Coronary Heart Disease Diagnosis in Women.

Physical mapping resources for large plant genomes: radiation hybrids for wheat D-genome progenitor Aegilops tauschii.

The Hypertriglyceridemic Waist, Waist-to-Height Ratio, and Cardiometabolic Risk.

Discovery and evolution of phenoxypiperidine hydroxyamide dual CCR3/H₁ antagonists. Part I.

Discovery of (5S,6S,9R)-5-amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-yl 4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxylate (BMS-927711): an oral calcitonin gene-related peptide (CGRP) antagonist in clinical trials for treating migraine.

Evaluation of whole effluent toxicity data characteristics and use of Welch's T-test in the test of significant toxicity analysis.

Implication of IL-2/IL-21 region in systemic sclerosis genetic susceptibility.

Comparison of surveillance strategies for low-risk bladder cancer patients.

The "his and hers" of the renin-angiotensin system.

An explanation for why it is difficult to form slush nitrogen from liquid nitrogen used previously for this purpose.

Update on the angiotensin AT(2) receptor.

Pressure and breast thickness in mammography--an exploratory calibration study.

Defining the molecular blueprint that drives CD8(+) T cell differentiation in response to infection.

KCNA5 gene is not confirmed as a systemic sclerosis-related pulmonary arterial hypertension genetic susceptibility factor.

Pharmacodynamics of selective inhibition of γ-secretase by avagacestat.

The clinical and functional outcomes of ultrasound-guided vs landmark-guided injections for adults with shoulder pathology--a systematic review and meta-analysis.

Borderline mean pulmonary artery pressure in patients with systemic sclerosis: transpulmonary gradient predicts risk of developing pulmonary hypertension.

The founding of the Howard Florey Institute of Experimental Physiology and Medicine.

Clinical characteristics, haemodynamics and treatment of pulmonary hypertension in sarcoidosis in a single centre, and meta-analysis of the published data.

Changes in the management of benign liver tumours: an analysis of 285 patients.

Mucin 5B promoter polymorphism is associated with idiopathic pulmonary fibrosis but not with development of lung fibrosis in systemic sclerosis or sarcoidosis.

The required written history and physical is alive, but not entirely well, in internal medicine clerkships.

Overnight call: a survey of medical student experiences, attitudes, and skills.

The elimination/challenge diet.

Decision Making about Risk of Infection by Young Adults with CF.

The systemic lupus erythematosus IRF5 risk haplotype is associated with systemic sclerosis.

Serum Interleukin 6 Is Predictive of Early Functional Decline and Mortality in Interstitial Lung Disease Associated with Systemic Sclerosis.

Practitioner compression force variability in mammography: a preliminary study.

Unmasking The Potential Of The At(2) r As A Therapeutic Target In Hypertension In Men And Women: What We Know And What We Still Need To Find Out.

Incidence of Spontaneous Non-Neoplastic Lesions in Transgenic CBYB6F1-Tg(HRAS)2Jic Mice.

Choice of activity-intensity classification thresholds impacts upon accelerometer-assessed physical activity-health relationships in children.

New insight on the Xq28 association with systemic sclerosis.

Wheat Zapper: a flexible online tool for colinearity studies in grass genomes.

A radiation hybrid map of chromosome 1D reveals synteny conservation at a wheat speciation locus.

C4 photosynthesis: from evolutionary analyses to strategies for synthetic reconstruction of the trait.

Halide and proton binding kinetics of yellow fluorescent protein variants.

Estimating the Cost of No-Shows and Evaluating the Effects of Mitigation Strategies.

Rectal Transmission of Transmitted/Founder HIV-1 Is Efficiently Prevented by Topical 1% Tenofovir in BLT Humanized Mice.

A Prognostic Nomogram for Prediction of Recurrence in Desmoid Fibromatosis.

Infertility and assisted reproduction: counselling and psychosocial aspects.

Targeted therapies for systemic sclerosis.

Cardiorespiratory Fitness Is Associated with Hard and Light Intensity Physical Activity but Not Time Spent Sedentary in 10-14 Year Old Schoolchildren: The HAPPY Study.