Michael Brand

The zebrafish spiel-ohne-grenzen (spg) gene encodes the POU domain protein Pou2 related to mammalian Oct4 and is essential for formation of the midbrain and hindbrain, and for pre-gastrula morphogenesis.

Spiel-ohne-grenzen/pou2 mediates regional competence to respond to Fgf8 during zebrafish early neural development.

Cloning and expression of Ventrhoid, a novel vertebrate homologue of the Drosophila EGF pathway gene rhomboid.

Retinoic acid signalling in the zebrafish embryo is necessary during pre-segmentation stages to pattern the anterior-posterior axis of the CNS and to induce a pectoral fin bud.

A novel positive transcriptional feedback loop in midbrain-hindbrain boundary development is revealed through analysis of the zebrafish pax2.1 promoter in transgenic lines.

Molecular characterization of Calymmin, a novel notochord sheath-associated extracellular matrix protein in the zebrafish embryo.

Pax2.1 is required for the development of thyroid follicles in zebrafish.

Association between mitochondrial dysfunction and severity and outcome of septic shock.

Patterning the zebrafish central nervous system.

Fgf8 and Fgf3 are required for zebrafish ear placode induction, maintenance and inner ear patterning.

Engrailed and Fgf8 act synergistically to maintain the boundary between diencephalon and mesencephalon.

Cloning, expression and relationship of zebrafish gbx1 and gbx2 genes to Fgf signaling.

Anger types and the use of cigarettes and smokeless tobacco among Native American adolescents.

Integrity of the midbrain region is required to maintain the diencephalic-mesencephalic boundary in zebrafish no isthmus/pax2.1 mutants.

Imaging brain development and organogenesis in zebrafish using immobilized embryonic explants.

Isthmus-to-midbrain transformation in the absence of midbrain-hindbrain organizer activity.

The POU domain protein spg (pou2/Oct4) is essential for endoderm formation in cooperation with the HMG domain protein casanova.

Isolation and expression of the homeobox gene Gbx1 during mouse development.

Zebrafish fgfr1 is a member of the fgf8 synexpression group and is required for fgf8 signalling at the midbrain-hindbrain boundary.

Endocytosis controls spreading and effective signaling range of Fgf8 protein.

Divide et Impera--the midbrain-hindbrain boundary and its organizer.

Distinct tissue-specificity of three zebrafish ext1 genes encoding proteoglycan modifying enzymes and their relationship to somitic Sonic hedgehog signaling.

Positioning of the midbrain-hindbrain boundary organizer through global posteriorization of the neuroectoderm mediated by Wnt8 signaling.

Self-assessment in the measurement of public health workforce preparedness for bioterrorism or other public health disasters.

Are public health workers aware of what they don't know?

Target-selected mutant screen by TILLING in Drosophila.

Lineage restriction maintains a stable organizer cell population at the zebrafish midbrain-hindbrain boundary.

Partnering for preparedness: the project public health ready experience.

Fgf signals from a novel signaling center determine axial patterning of the prospective neural retina.

Global and local mechanisms of forebrain and midbrain patterning.

Hedgehog signalling from the zona limitans intrathalamica orchestrates patterning of the zebrafish diencephalon.

Analysis and visualization of cell movement in the developing zebrafish brain.

Neural stem cells and neurogenesis in the adult zebrafish brain: origin, proliferation dynamics, migration and cell fate.

Maternal control of vertebrate dorsoventral axis formation and epiboly by the POU domain protein Spg/Pou2/Oct4.

Pbx proteins cooperate with Engrailed to pattern the midbrain-hindbrain and diencephalic-mesencephalic boundaries.

Proliferation, neurogenesis and regeneration in the non-mammalian vertebrate brain.

Early developmental specification of the thyroid gland depends on han-expressing surrounding tissue and on FGF signals.

Micro fluid segment technique for screening and development studies on Danio rerio embryos.

Learning from Katrina: environmental health observations from the SWCPHP response team in Houston.

The endosomal protein Appl1 mediates Akt substrate specificity and cell survival in vertebrate development.

Implications of public understanding of avian influenza for fostering effective risk communication.

Temporally-controlled site-specific recombination in zebrafish.

Zebrafish gbx1 refines the midbrain-hindbrain boundary border and mediates the Wnt8 posteriorization signal.

Tissue micromanipulation in zebrafish embryos.

Stem cells in the adult zebrafish cerebellum: initiation and maintenance of a novel stem cell niche.

Modular scanning FCS quantifies receptor-ligand interactions in living multicellular organisms.

Duplication of fgfr1 permits Fgf signaling to serve as a target for selection during domestication.

Fgf8 morphogen gradient forms by a source-sink mechanism with freely diffusing molecules.

Dynamic coupling of pattern formation and morphogenesis in the developing vertebrate retina.

Heterogeneity and Fgf dependence of adult neural progenitors in the zebrafish telencephalon.

Generation of a non-leaky heat shock-inducible Cre line for conditional Cre/lox strategies in zebrafish.

Boundary formation and maintenance in tissue development.

Interpretation of the FGF8 morphogen gradient is regulated by endocytic trafficking.

Distinct and conserved prominin-1/CD133-positive retinal cell populations identified across species.

Compressed Genotyping.

Dose reduction in abdominal computed tomography: intraindividual comparison of image quality of full-dose standard and half-dose iterative reconstructions with dual-source computed tomography.

Zebrafish limb development is triggered by a retinoic acid signal during gastrulation.

Bone regenerates via dedifferentiation of osteoblasts in the zebrafish fin.

Adult neurogenesis and brain regeneration in zebrafish.

Which concentration to choose in dual flow cardiac CT?: dual flow cardiac CT.

Cxcl12 evolution--subfunctionalization of a ligand through altered interaction with the chemokine receptor.

Mutant generation in vertebrate model organisms by TILLING.

Subdivisions of the adult zebrafish subpallium by molecular marker analysis.

Regeneration of the adult zebrafish brain from neurogenic radial glia-type progenitors.

Cerebroventricular microinjection (CVMI) into adult zebrafish brain is an efficient misexpression method for forebrain ventricular cells.

X-ray induced DNA double-strand breaks in coronary CT angiography: comparison of sequential, low-pitch helical and high-pitch helical data acquisition.

Fgf Signaling is Required for Photoreceptor Maintenance in the Adult Zebrafish Retina.

Latino/as in substance abuse treatment: substance use patterns, family history of addiction, and depression.

Effect of antioxidants on X-ray-induced γ-H2AX foci in human blood lymphocytes: preliminary observations.

β-arrestin control of late endosomal sorting facilitates decoy receptor function and chemokine gradient formation.

The chemokine receptor cxcr5 regulates the regenerative neurogenesis response in the adult zebrafish brain.

Induction and repair of DNA double-strand breaks in blood lymphocytes of patients undergoing (18)F-FDG PET/CT examinations.

Acute inflammation initiates the regenerative response in the adult zebrafish brain.

Regenerative neurogenesis from neural progenitor cells requires injury-induced expression of Gata3.

Comparative aspects of adult neural stem cell activity in vertebrates.

The effect of calyculin A on the dephosphorylation of the histone γ-H2AX after formation of X-ray-induced DNA double-strand breaks in human blood lymphocytes.

Substance abuse patterns and psychiatric symptomatology among three healthcare provider groups evaluated in an out-patient program for impaired healthcare professionals.

Morphogen transport.

Zebrafish Foxi1 provides a neuronal ground state during inner ear induction preceding the Dlx3b/4b-regulated sensory lineage.

Development and specification of cerebellar stem and progenitor cells in zebrafish: from embryo to adult.

The Zebrafish CreZoo: An Easy-to-Handle Database for Novel CreER(T2)-Driver Lines.

Generation and interpretation of FGF morphogen gradients in vertebrates.