Jonathan F. Lovell

Bcl-XL inhibits membrane permeabilization by competing with Bax.

A tumor mRNA-triggered photodynamic molecular beacon based on oligonucleotide hairpin control of singlet oxygen production.

Membrane binding by tBid initiates an ordered series of events culminating in membrane permeabilization by Bax.

FRET quenching of photosensitizer singlet oxygen generation.

Biomimetic nanocarrier for direct cytosolic drug delivery.

HDL-mimicking peptide-lipid nanoparticles with improved tumor targeting.

Activatable photosensitizers for imaging and therapy.

Facile synthesis of advanced photodynamic molecular beacon architectures.

Programmed nanoparticle aggregation using molecular beacons.

Cytosolic delivery of LDL nanoparticle cargo using photochemical internalization.

Efficient cytosolic delivery of siRNA using HDL-mimicking nanoparticles.

Porphysome nanovesicles generated by porphyrin bilayers for use as multimodal biophotonic contrast agents.

Lipoprotein-inspired nanoparticles for cancer theranostics.

Porphyrin-cross-linked hydrogel for fluorescence-guided monitoring and surgical resection.

Biodegradable star polymers shine for cancer drug delivery.

Porphyrin FRET acceptors for apoptosis induction and monitoring.

Downsizing nanoparticles for better tumor penetration and accumulation.

Bursting the bubble: microbubble–nanoparticle composites for ultrasound-mediated drug delivery.

A challenger appears: a copper nanocolloid for MR detection of atherosclerotic plaques.

A new endogenous and immunologically inert siRNA delivery vehicle for targeting the brain.

Mechanistic insights into LDL nanoparticle-mediated siRNA delivery.

Enzymatic regioselection for the synthesis and biodegradation of porphysome nanovesicles.

Porphyrin shell microbubbles with intrinsic ultrasound and photoacoustic properties.

Porphyrins and phthalocyanines for theranostics.

Porphyrins as theranostic agents from prehistoric to modern times.

Ablation of hypoxic tumors with dose-equivalent photothermal, but not photodynamic, therapy using a nanostructured porphyrin assembly.

Self-assembled porphyrin nanodiscs with structure-dependent activation for phototherapy and photodiagnostic applications.

The use of nanoparticulate delivery systems in metronomic chemotherapy.