Francesca Granucci

IL-2 mediates adjuvant effect of dendritic cells.

Granulocyte-macrophage colony-stimulating factor induces an expression program in neonatal microglia that primes them for antigen presentation.

Toll-like receptor 4 is not required for the full maturation of dendritic cells or for the degradation of Gram-negative bacteria.

Opinion: Interpretation of the complexity of innate immune responses by functional genomics.

Interactions of bacterial pathogens with dendritic cells during invasion of mucosal surfaces.

Early IL-2 production by mouse dendritic cells is the result of microbial-induced priming.

Dendritic cell regulation of immune responses: a new role for interleukin 2 at the intersection of innate and adaptive immunity.

The immune response is initiated by dendritic cells via interaction with microorganisms and interleukin-2 production.

The scavenger receptor MARCO mediates cytoskeleton rearrangements in dendritic cells and microglia.

A type I IFN-dependent pathway induced by Schistosoma mansoni eggs in mouse myeloid dendritic cells generates an inflammatory signature.

The regulatory role of dendritic cells in the immune response.

A contribution of mouse dendritic cell-derived IL-2 for NK cell activation.

The European dimension for the mouse genome mutagenesis program.

Dendritic cell-derived IL-2 production is regulated by IL-15 in humans and in mice.

A central role for tissue-resident dendritic cells in innate responses.

A power law global error model for the identification of differentially expressed genes in microarray data.

A critical role for lipophosphoglycan in proinflammatory responses of dendritic cells to Leishmania mexicana.

Differential expression regulation of the alpha and beta subunits of the PA28 proteasome activator in mature dendritic cells.

TLR-dependent activation stimuli associated with Th1 responses confer NK cell stimulatory capacity to mouse dendritic cells.

Synthesis and biological evaluation of novel lipid A antagonists.

Dendritic cell biology.

Induction of peripheral T cell tolerance by antigen-presenting B cells. I. Relevance of antigen presentation persistence.

Induction of peripheral T cell tolerance by antigen-presenting B cells. II. Chronic antigen presentation overrules antigen-presenting B cell activation.

Dendritic cells in pathogen recognition and induction of immune responses: a functional genomics approach.

Effects of dexamethazone on LPS-induced activationand migration of mouse dendritic cells revealed by a genome-wide transcriptional analysis.

Natural killer (NK) cell functions can be strongly boosted by activated dendritic cells (DC).

Inhibition of lipid a stimulated activation of human dendritic cells and macrophages by amino and hydroxylamino monosaccharides.

Self-tolerance, dendritic cell (DC)-mediated activation and tissue distribution of natural killer (NK) cells.

Gene expression profiling of dendritic cells by microarray.

Central role of dendritic cells in the regulation and deregulation of immune responses.

Image filtering for two-photon deep imaging of lymphonodes.

Role of Toll like receptor-activated dendritic cells in the development of autoimmunity.

Glial TLR4 receptor as new target to treat neuropathic pain: efficacy of a new receptor antagonist in a model of peripheral nerve injury in mice.

Generation of murine growth factor-dependent long-term dendritic cell lines to investigate host-parasite interactions.

CD14 regulates the dendritic cell life cycle after LPS exposure through NFAT activation.

The dendritic cell life cycle.

Straightforward synthesis of novel Akt inhibitors based on a glucose scaffold.

Gene expression profiles identify inflammatory signatures in dendritic cells.

Regulation of antigen uptake, migration, and lifespan of dendritic cell by Toll-like receptors.

Differences in lipopolysaccharide-induced signaling between conventional dendritic cells and macrophages.

The regulatory role of dendritic cells in the induction and maintenance of T-cell tolerance.

Deciphering the complexity of Toll-like receptor signaling.

A dairy bacterium displays in vitro probiotic properties for the pharyngeal mucosa by antagonizing group A streptococci and modulating the immune response.

Accumulative difference image protocol for particle tracking in fluorescence microscopy tested in mouse lymphonodes.

DC-ATLAS: a systems biology resource to dissect receptor specific signal transduction in dendritic cells.

Uniform lipopolysaccharide (LPS)-loaded magnetic nanoparticles for the investigation of LPS-TLR4 signaling.

Vaccination with filamentous bacteriophages targeting DEC-205 induces DC maturation and potent anti-tumor T-cell responses in the absence of adjuvants.

CD14 controls the LPS-induced endocytosis of Toll-like receptor 4.

Similarities and differences of innate immune responses elicited by smooth and rough LPS.

CD14 and NFAT mediate lipopolysaccharide-induced skin edema formation in mice.

Regulation and dysregulation of innate immunity by NFAT signaling downstream of pattern recognition receptors (PRRs).

Migratory, and not lymphoid-resident, dendritic cells maintain peripheral self-tolerance and prevent autoimmunity via induction of iTreg cells.

The timing of IFNβ production affects early innate responses to Listeria monocytogenes and determines the overall outcome of lethal infection.

EFIS-EJI Ita Askonas Award. Q&A with Francesca Granucci, winner of the EFIS-EJI Ita Askonas Award 2012.

The nature of activatory and tolerogenic dendritic cell-derived signal 2.

Migratory conventional dendritic cells in the induction of peripheral T cell tolerance.

Role of CD14 in host protection against infections and in metabolism regulation.

Systemically administered DNA and fowlpox recombinants expressing four vaccinia virus genes although immunogenic do not protect mice against the highly pathogenic IHD-J vaccinia strain.

IL-15 cis presentation is required for optimal NK cell activation in lipopolysaccharide-mediated inflammatory conditions.

Modeling leukocyte-leukocyte non-contact interactions in a lymph node.

Wiskott-Aldrich syndrome protein deficiency in natural killer and dendritic cells affects antitumor immunity.

Modulation of CD14 and TLR4·MD-2 activities by a synthetic lipid A mimetic.

The nature of activatory and tolerogenic dendritic cell-derived signal 2.

rBet v 1 immunotherapy of sensitized mice with Streptococcus thermophilus as vehicle and adjuvant.

Murein lytic enzyme TgaA of Bifidobacterium bifidum MIMBb75 modulates dendritic cell maturation through its cysteine- and histidine-dependent amidohydrolase/peptidase (CHAP) amidase domain.

Microbe- and danger-induced inflammation.

"Endotoxin, TLR4 signaling and beyond".

Cream formulation impact on topical administration of engineered colloidal nanoparticles.

A role for CCR5(+)CD4 T cells in cutaneous psoriasis and for CD103(+) CCR4(+) CD8 Teff cells in the associated systemic inflammation.

Prolonged contact with dendritic cells turns lymph node-resident NK cells into anti-tumor effectors.

Blood to skin recirculation of CD4 memory T cells associates with cutaneous and systemic manifestations of psoriatic disease.

Inflammatory role of dendritic cells in Amyotrophic Lateral Sclerosis revealed by an analysis of patients' peripheral blood.

IFN-λ suppresses intestinal inflammation by non-translational regulation of neutrophil function.

Drug nanocarriers to treat autoimmunity and chronic inflammatory diseases.

Skin infections are eliminated by cooperation of the fibrinolytic and innate immune systems.

Nanoparticles: "magic bullets" for targeting the immune system.

Interferon (IFN)-λ Takes the Helm: Immunomodulatory Roles of Type III IFNs.

The Family of LPS Signal Transducers Increases: the Arrival of Chanzymes.

Toll-like receptor 4 modulation influences human neural stem cell proliferation and differentiation.