Graham Hatfull

Growth of Mycobacterium tuberculosis biofilms containing free mycolic acids and harbouring drug-tolerant bacteria.

Microbiology. A tail of two specifi-cities.

Bacteriophage Mu genome sequence: analysis and comparison with Mu-like prophages in Haemophilus, Neisseria and Deinococcus.

Imbroglios of viral taxonomy: genetic exchange and failings of phenetic approaches.

Integration and excision of the Mycobacterium tuberculosis prophage-like element, phiRv1.

Specialized transduction: an efficient method for generating marked and unmarked targeted gene disruptions in Mycobacterium tuberculosis, M. bovis BCG and M. smegmatis.

Corrected sequence of the bacteriophage p22 genome.

Control of directionality in L5 integrase-mediated site-specific recombination.

Origins of highly mosaic mycobacteriophage genomes.

Bacteriophages with tails: chasing their origins and evolution.

Rapid identification and susceptibility testing of Mycobacterium tuberculosis from MGIT cultures with luciferase reporter mycobacteriophages.

Mycobacteriophage Bxb1 integrates into the Mycobacterium smegmatis groEL1 gene.

The orientation of mycobacteriophage Bxb1 integration is solely dependent on the central dinucleotide of attP and attB.

The pKO2 linear plasmid prophage of Klebsiella oxytoca.

Complete genomic sequence of the virulent Salmonella bacteriophage SP6.

Bxz1, a new generalized transducing phage for mycobacteria.

The generalized transducing Salmonella bacteriophage ES18: complete genome sequence and DNA packaging strategy.

2004 ASM Conference on the New Phage Biology: the 'Phage Summit'.

Integration and excision by the large serine recombinase phiRv1 integrase.

Synapsis in phage Bxb1 integration: selection mechanism for the correct pair of recombination sites.

GroEL1: a dedicated chaperone involved in mycolic acid biosynthesis during biofilm formation in mycobacteria.

Control of phage Bxb1 excision by a novel recombination directionality factor.

Exploring the mycobacteriophage metaproteome: phage genomics as an educational platform.

Efficient site-specific integration in Plasmodium falciparum chromosomes mediated by mycobacteriophage Bxb1 integrase.

Mycobacteriophage exploit NHEJ to facilitate genome circularization.

A peptidoglycan hydrolase motif within the mycobacteriophage TM4 tape measure protein promotes efficient infection of stationary phase cells.

Recombineering in Mycobacterium tuberculosis.

Inquiry learning. Teaching scientific inquiry.

Genome sequence, structural proteins, and capsid organization of the cyanophage Syn5: a "horned" bacteriophage of marine synechococcus.

Genomic and structural analysis of Syn9, a cyanophage infecting marine Prochlorococcus and Synechococcus.

Comparative genomic analysis of mycobacteriophage Tweety: evolutionary insights and construction of compatible site-specific integration vectors for mycobacteria.

The role of iron in Mycobacterium smegmatis biofilm formation: the exochelin siderophore is essential in limiting iron conditions for biofilm formation but not for planktonic growth.

Genomic characterization of mycobacteriophage Giles: evidence for phage acquisition of host DNA by illegitimate recombination.

Efficient point mutagenesis in mycobacteria using single-stranded DNA recombineering: characterization of antimycobacterial drug targets.

Two-step site selection for serine-integrase-mediated excision: DNA-directed integrase conformation and central dinucleotide proofreading.

Mycobacterial recombineering.

Exploring the prokaryotic virosphere.

Comparative genomics of the mycobacteriophages: insights into bacteriophage evolution.

Bacteriophage genomics.

Recombineering mycobacteria and their phages.

BRED: a simple and powerful tool for constructing mutant and recombinant bacteriophage genomes.

The genome of Bacillus subtilis bacteriophage SPO1.

Fluoromycobacteriophages for rapid, specific, and sensitive antibiotic susceptibility testing of Mycobacterium tuberculosis.

Mycobacteriophage Lysin B is a novel mycolylarabinogalactan esterase.

Mycobacteriophages BPs, Angel and Halo: comparative genomics reveals a novel class of ultra-small mobile genetic elements.

Comparative genomic analysis of 60 Mycobacteriophage genomes: genome clustering, gene acquisition, and gene size.

Do mycobacteria produce endospores?

Enzymatic hydrolysis of trehalose dimycolate releases free mycolic acids during mycobacterial growth in biofilms.

Temperature-dependent regulation of mycolic acid cyclopropanation in saprophytic mycobacteria: role of the Mycobacterium smegmatis 1351 gene (MSMEG_1351) in CIS-cyclopropanation of alpha-mycolates.

Mycobacteriophages: genes and genomes.

Expanding the diversity of mycobacteriophages: insights into genome architecture and evolution.

Evaluation of fluoromycobacteriophages for detecting drug resistance in Mycobacterium tuberculosis.

Single-molecule analysis reveals the molecular bearing mechanism of DNA strand exchange by a serine recombinase.

Successive and targeted DNA integrations in the Drosophila genome by Bxb1 and phiC31 integrases.

Evaluation of a transposase protocol for rapid generation of shotgun high-throughput sequencing libraries from nanogram quantities of DNA.

Phamerator: a bioinformatic tool for comparative bacteriophage genomics.

Reporter phage and breath tests: emerging phenotypic assays for diagnosing active tuberculosis, antibiotic resistance, and treatment efficacy.

Bacteriophages and their Genomes.

Cluster K mycobacteriophages: insights into the evolutionary origins of mycobacteriophage TM4.

Competencies: a cure for pre-med curriculum.

The Bxb1 gp47 recombination directionality factor is required not only for prophage excision, but also for phage DNA replication.

2GFP10: A high-intensity fluorophage enables detection and rapid drug susceptibility testing of Mycobacterium tuberculosis directly from sputum samples.

Complete Genome Sequences of 138 Mycobacteriophages.