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Department of Microbiology & Immunology
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Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease.
Nature Jan, 2002 | Pubmed ID: 11823861
T cell response in experimental autoimmune encephalomyelitis (EAE): role of self and cross-reactive antigens in shaping, tuning, and regulating the autopathogenic T cell repertoire.
Annual review of immunology , 2002 | Pubmed ID: 11861599
Detection of autoreactive myelin proteolipid protein 139-151-specific T cells by using MHC II (IAs) tetramers.
Journal of immunology (Baltimore, Md. : 1950) Jan, 2003 | Pubmed ID: 12517952
Activation of antigen-presenting cells by microbial products breaks self tolerance and induces autoimmune disease.
The Journal of clinical investigation Apr, 2004 | Pubmed ID: 15057305
Disease-related epitope spread in a humanized T cell receptor transgenic model of multiple sclerosis.
European journal of immunology Jul, 2004 | Pubmed ID: 15214032
Cross-reactive TCR responses to self antigens presented by different MHC class II molecules.
Journal of immunology (Baltimore, Md. : 1950) Aug, 2004 | Pubmed ID: 15265898
Modified amino acid copolymers suppress myelin basic protein 85-99-induced encephalomyelitis in humanized mice through different effects on T cells.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2004 | Pubmed ID: 15292513
High incidence of spontaneous disease in an HLA-DR15 and TCR transgenic multiple sclerosis model.
Journal of immunology (Baltimore, Md. : 1950) Feb, 2005 | Pubmed ID: 15699121
Epitope spreading initiates in the CNS in two mouse models of multiple sclerosis.
Nature medicine Mar, 2005 | Pubmed ID: 15735651
TIM-4 is the ligand for TIM-1, and the TIM-1-TIM-4 interaction regulates T cell proliferation.
Nature immunology May, 2005 | Pubmed ID: 15793576
Specific T regulatory cells display broad suppressive functions against experimental allergic encephalomyelitis upon activation with cognate antigen.
Journal of immunology (Baltimore, Md. : 1950) Jun, 2005 | Pubmed ID: 15905518
T cell tolerance induced by cross-reactive TCR ligands can be broken by superagonist resulting in anti-inflammatory T cell cytokine production.
Journal of immunology (Baltimore, Md. : 1950) Aug, 2005 | Pubmed ID: 16034086
Cutting edge: CD4+CD25+ regulatory T cells contribute to gender differences in susceptibility to experimental autoimmune encephalomyelitis.
Journal of immunology (Baltimore, Md. : 1950) Nov, 2005 | Pubmed ID: 16237044
Copolymer effects on microglia and T cells in the central nervous system of humanized mice.
European journal of immunology Dec, 2005 | Pubmed ID: 16259003
Induction of oral tolerization in CD86 deficient mice: a role for CD86 and B cells in the up-regulation of TGF-beta.
Journal of autoimmunity Mar, 2006 | Pubmed ID: 16439314
The autoimmune diabetes locus Idd9 regulates development of type 1 diabetes by affecting the homing of islet-specific T cells.
Journal of immunology (Baltimore, Md. : 1950) May, 2006 | Pubmed ID: 16622013
Identifying druglike inhibitors of myelin-reactive T cells by phenotypic high-throughput screening of a small-molecule library.
Journal of biomolecular screening Jun, 2007 | Pubmed ID: 17478482
Modulation of CD4 co-receptor limits spontaneous autoimmunity when high-affinity transgenic TCR specific for self-antigen is expressed on a genetically resistant background.
International immunology Oct, 2007 | Pubmed ID: 17804690
Inhibition of experimental autoimmune myocarditis: peripheral deletion of TcR Vbeta 8.1, 8.2+ CD4+ T cells in TLR-4 deficient mice.
Journal of autoimmunity Sep, 2008 | Pubmed ID: 18715752
The role of innate immune responses in autoimmune disease development.
Autoimmunity reviews Mar, 2009 | Pubmed ID: 19162250
Halofuginone inhibits TH17 cell differentiation by activating the amino acid starvation response.
Science (New York, N.Y.) Jun, 2009 | Pubmed ID: 19498172
Promoting tolerance to proteolipid protein-induced experimental autoimmune encephalomyelitis through targeting dendritic cells.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2010 | Pubmed ID: 20855626
The innate immune adaptor MyD88 is dispensable for spontaneous autoimmune demyelination in a mouse model of multiple sclerosis.
Journal of neuroimmunology Feb, 2013 | Pubmed ID: 23269203
Pennsylvania State University College of Medicine
Gregory Berry1,
Hanspeter Waldner1
1Department of Microbiology & Immunology, Pennsylvania State University College of Medicine
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