Using Inducible Osteoblastic Lineage-Specific Stat3 Knockout Mice to Study Alveolar Bone Remodeling During Orthodontic Tooth MovementYuanqi Liu *1,2,3,4,5, Siyuan Sun *1,2,3,4,5, Ziyi Jiang *6, Xinyi Gong 1,2,3,4,5, Yiling Yang 1,2,3,4,5, Yanfei Zhu 1,2,3,4,5, Hongyuan Xu 1,2,3,4,5, Anting Jin 1,2,3,4,5, Xiangru Huang 1,2,3,4,5, Xin Gao 1,2,3,4,5, Tingwei Lu 1,2,3,4,5, Jingyi Liu 1,2,3,4,5, Xinyu Wang 1,2,3,4,5, Qinggang Dai 2,3,4,5,7, Lingyong Jiang 1,2,3,4,5
1Center of Craniofacial Orthodontics, Department of Oral and Cranio-maxillofacial Surgery, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, 2College of Stomatology, Shanghai Jiao Tong University, 3National Center for Stomatology, 4National Clinical Research Center for Oral Diseases, 5Shanghai Key Laboratory of Stomatology, 6Shanghai Starriver Bilingual School, 7The 2nd Dental Center, Ninth People’s Hospital, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine
This study provides a protocol for using inducible osteoblast lineage-specific Stat3 knockout mice to study bone remodeling under orthodontic force and describes methods for analyzing alveolar bone remodeling during orthodontic tooth movement, thus shedding light on skeletal mechanical biology.
