Handcrafted Silicone Coated Filament for Mice Middle Cerebral Artery Occlusion ModelsMin Zhang 1,2, Yitong Yuan 3, Ruochen Du 3, Chunli Wen 1, Shiqin Lin 2, Yaqiong Zhang 2, Zhenyu Xiang 4, Fengyun Hu 1, Chunfang Wang 3
1Department of Neurology, Fifth Hospital of Shanxi Medical University, Shanxi Provincial People's Hospital, 2Department of Neurology, Taiyuan Central Hospital, Shan Xi Medical University, 3Experimental Animal Center, Shanxi Medical University, 4Collaborative Innovation Center for Molecular Imaging of Precision Medicine, Shan Xi Medical University
This protocol describes a straightforward method for creating coated filaments for the middle cerebral artery occlusion (MCAO) model in mice using silicone, nylon sutures, and syringe needles. This method allows for the production of filaments with a consistent diameter and various silicone wrapping lengths tailored to experimental needs.
