Zebra II as A Novel System to Record Electrophysiological Signals in ZebrafishRamses Seferino Trigo Torres 1, Mao-Hsiang Huang 2, Mohamed Benomar 2, Tai Le 1, Tim Etchells 3, Xiaolei Xu 4, Michael P. H. Lau 3, Hung Cao 1,2
1Department of Biomedical Engineering, UC Irvine, 2Department of Electrical Engineering and Computer Science, UC Irvine, 3Sensoriis Inc., 4Department of Biochemistry and Molecular Biology, Mayo Clinic
The study introduces Zebra II, an advanced system for prolonged ECG acquisition and analysis in zebrafish. This system features an independent perfusion system and multiple-point electrodes for handling multiple fish in controlled environments. Acute effects of Amiodarone were assessed and analyzed with wild-type zebrafish.
