Conditional Reprogramming of Pediatric Human Esophageal Epithelial Cells for Use in Tissue Engineering and Disease InvestigationTodd J. Jensen 1, Christopher Foster 1, Wael Sayej 2, Christine M. Finck 3
1Department of Pediatrics, UConn Health, 2Department of Gastroenterology, Connecticut Children's Medical Center, 3Department of Surgery, Connecticut Children's Medical Center
Expansion of human pediatric esophageal epithelial cells utilizing conditional reprogramming provides investigators with a patient-specific population of cells that can be utilized for engineering esophageal constructs for autologous implantation to treat defects or injury and serve as a reservoir for therapeutic screening assays.