Assessment of Ovarian Cancer Spheroid Attachment and Invasion of Mesothelial Cells in Real TimeMaree Bilandzic 1, Kaye L. Stenvers 1,2
1Reproductive Development and Cancer Laboratory, MIMR-PHI Institute of Medical Research, 2Department of Developmental Biology and Anatomy, Monash University
Ovarian cancer cell invasion into the mesothelial lining of the peritoneum is a dynamic process over time. Utilizing a real time analyzer, the invasive capacity of ovarian cancer cells in a spheroid-mesothelial cell co-culture model can be quantified over prolonged time periods, providing insights into factors regulating the metastatic process.
