Determining the Optimal Inhibitory Frequency for Cancerous Cells Using Tumor Treating Fields (TTFields)Yaara Porat 1, Moshe Giladi 1, Rosa S. Schneiderman 1, Roni Blat 1, Anna Shteingauz 1, Einav Zeevi 1, Mijal Munster 1, Tali Voloshin 1, Noa Kaynan 1, Orna Tal 1, Eilon D. Kirson 2, Uri Weinberg 3, Yoram Palti 2
1Preclinical Research Department, Novocure Ltd., Haifa, Israel, 2Novocure Ltd., Haifa, Israel, 3Novocure GmbH, Lucerne, Switzerland
Tumor Treating Fields (TTFields) are an effective anti-tumor treatment modality delivered via the continuous, noninvasive application of low-intensity, intermediate-frequency, alternating electric fields. TTFields application to cell lines using a TTFields in vitro application system allows for the determination of the optimal frequency that leads to the highest reduction in cell counts.
