Laminotomy for Lumbar Dorsal Root Ganglion Access and Injection in SwineMark D. Unger 1, Timothy P. Maus 2, Ross C. Puffer 3, Laura K. Newman 1, Bradford L. Currier 4, Andreas S. Beutler 1
1Departments of Anesthesiology and Oncology, Mayo Clinic, Translational Science Track, Mayo Graduate School, 2Department of Radiology (Section of Interventional Pain Management), Mayo Clinic, 3Department of Neurologic Surgery, Mayo Clinic, 4Department of Orthopedic Surgery, Mayo Clinic
We describe a method for laminotomy in swine that provides access to lumbar dorsal root ganglia (DRG) for intraganglionic injection. Injection progress is monitored intraoperatively and histologically confirmed up to 21 days after surgery. This protocol could be used for future preclinical studies involving DRG injection.
