Eaton Industries (Austria) GmbH
2 ARTICLES PUBLISHED IN JoVE
Medicine
Semi-Minimal Invasive Method to Induce Myocardial Infarction in Rats and the Assessment of Cardiac Function by an Isolated Working Heart System
Patrick M. Pilz 1, Miriam Lang 1, Ouafa Hamza 1, Petra L. Szabo 1, Milat Inci 1, Anne M. Kramer 1, Michael Koch 2, Johann Huber 3, Bruno K. Podesser 1, Attila Kiss 1
1Ludwig-Boltzmann-Institute for Cardiovascular Research at the Center for Biomedical Research, Medical University of Vienna, 2Concept & Ideation, Electrical Sector/EMEA/Power Distribution Division, Eaton Industries (Austria) GmbH, 3Vetfarm and Clinical Unit for Herd Health Management in Ruminants, Clinic for Ruminants, Vetmeduni Vienna
This article presents an efficient method to perform myocardial ischemia and subsequent chronic reperfusion in rats using a minimally invasive approach. In addition, left ventricular hemodynamic function of rats is assessed by echocardiography and isolated working heart methods.
Behavior
An Open-Source, Fully Customizable 5-Choice Serial Reaction Time Task Toolbox for Automated Behavioral Training of Rodents
Julia Morais Gancz 1, Nada El Jundi 2, Eva Strippelmann 2, Michael Koch 2, Detlef Wegener 1
1Cognitive Neurophysiology Department, Brain Research Institute, University of Bremen, 2Neuropharmacology Department, Brain Research Institute, University of Bremen
The present protocol describes the development of an open-source 5-choice serial reaction time task toolbox for rodent animal models, using Arduino and related hardware and a versatile Matlab toolbox, including an optional script for automated behavioral training. The scripts are customizable and facilitate the implementation of different trial-and-test designs.
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