A Robust Discovery Platform for the Identification of Novel Mediators of Melanoma MetastasisArman Alberto Sorin Shadaloey 1,2, Alcida Karz 1,2, Rana S. Moubarak 1,2, Praveen Agrawal 1,2, Grace Levinson 1,2, Kevin Kleffman 1,2, Orlando Aristizabal 3,4, Iman Osman 2,5, Youssef Z. Wadghiri 3,4, Eva Hernando 1,2
1Department of Pathology, NYU Grossman School of Medicine, 2Interdisciplinary Melanoma Cooperative Group, Perlmutter Cancer Center, 3Department of Radiology, NYU Grossman School of Medicine, 4Preclinical Imaging Core, NYU Grossman School of Medicine, 5Ronald Perelman Department of Dermatology, NYU Grossman School of Medicine
This article describes a workflow of techniques employed for testing novel candidate mediators of melanoma metastasis and their mechanism(s) of action.