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Cancer Research

Proximity Ligation Assay Allows the Detection, Localization, and Quantification of Protein Arginine Methylation in Fixed Tissue
Coralie Poulard *1,2,3, Julien Jacquemetton *1,2,3, Julie Valantin 1,2,3,4,5, Isabelle Treilleux 1,2,3,4, Muriel Le Romancer 1,2,3
1Université de Lyon, 2Inserm U1052, Centre de Recherche en Cancérologie de Lyon, 3CNRS UMR5286, Centre de Recherche en Cancérologie de Lyon, 4Pathology Department, Centre Leon Bérard, 5Plateforme Anatomopathologie Recherche

Proximity ligation assay is a very useful technique to localize and quantify arginine methylation of a given protein when the modified arginine residue is unknown and/or if no specific antibody is available.

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