Source: Kay Stewart, RVT, RLATG, CMAR; Valerie A. Schroeder, RVT, RLATG. University of Notre Dame, IN

The Guide for the Care and Use of Laboratory Animals ("The Guide") states that pain assessment and alleviation are integral components of the veterinary care of laboratory animals.¹ The definition of anesthesia is the loss of feeling or sensation. It is a dynamic event involving changes in anesthetic depth with respect to an animal's metabolism, surgical stimulation, or variations in the external environment.

The proper choice of anesthetics for surgery and other potentially painful procedures must be determined by a veterinarian. This is based on numerous aspects, including the extent and duration of the procedure, the species and strain, the age, and the physiological status of the animal.

Anesthetics are available as inhalants or injectables. Surgical anesthesia can be accomplished using a combination of injectable and inhalant anesthetics.²

1. Inhalant anest

The proper use of anesthetics for surgery, or other potentially painful procedures, is crucial not only for the animal's wellbeing, but also for the integrity of the scientific data collected during the procedure. There are many variables that factor into choosing the appropriate anesthetic regiment. The depth of anesthesia must be closely monitored, as each individual animal can respond differently to the drug. With the use of the proper anesthetic and careful monitoring, painful procedures can be accomplished with

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