Ringraziamo partecipano bambini e le famiglie, tutto il personale presso l&#39;Ospedale dei Bambini di Boston (CHB) con particolare apprezzamento ai tecnici risonanza magnetica, senza il quale i nostri studi non è stato possibile condurre. Siamo particolarmente grati ad Arnold Cyr di partecipazione e di aiuto durante le nostre riprese video e al funzionamento direttore Patricia Devine a Waltham CHB. Grazie alla ricerca e allo staff tecnico al MIT di Athinoula A. Martinos Imaging Center per la condivisione di esperienza nella acquisizione delle immagini RM e analisi. Questa ricerca è stata finanziata dalla Fondazione H. Charles Hood, un ospedale pediatrico di Boston pilota sovvenzione e il Fondo nazionale svizzero (NMR)

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The authors have nothing to disclose.

L&#39;emergere di risonanza magnetica funzionale e strutturale per studiare il cervello umano ha facilitato le possibilità di esaminare tipici così come la struttura cerebrale atipica e funzioni e detiene quindi una grande promessa sia per scopi di ricerca e clinica 6. Tuttavia, studi di risonanza magnetica nelle fasce d&#39;età più giovani rimangono meno numerosi rispetto a quelli degli adulti, adolescenti o bambini, che è principalmente a causa di difficoltà tecniche e pratic...

making mr imaging child's play - pediatric neuroimaging protocol, guidelines and procedure

Nell&#39;ultimo decennio c&#39;è stato un aumento dell&#39;uso di strutturale e la risonanza magnetica funzionale (fMRI) per studiare le basi neuronali della percezione umana, la cognizione e del comportamento<sup&gt; 1, 2</sup&gt;. Inoltre, questo metodo non invasivo di imaging si è trasformata in uno strumento per i medici e ricercatori per esplorare lo sviluppo del cervello tipico e atipico. Anche se i progressi in strumenti di neuroimaging e le tecniche sono evidenti, (f), risonanza magnetica in giovani pazienti pediatrici è relativamente infrequente<sup&gt; 2</sup&gt;. Sfide pratiche e tecniche di imaging, quando i bambini presenti i clinici e gruppi di ricerca con un unico insieme di problemi<sup&gt; 3, 2</sup&gt;. Per citarne solo alcuni, i partecipanti si sono sfidati bambino da un bisogno di motivazione, la vigilanza e la cooperazione. L&#39;ansia può essere un ulteriore fattore da affrontare. Ricercatori o medici devono considerare vincoli di tempo, limitazione di movimento, il rumore di fondo dello scanner e scarsa familiarità con l&#39;ambiente scanner MR<sup&gt; 2,4-10</sup&gt;. Un uso progressivo di neuroimaging funzionale e strutturale nelle fasce di età più giovani, però, potrebbe ulteriormente aggiungere alla nostra comprensione dello sviluppo cerebrale. Per fare un esempio, molti gruppi di ricerca stanno attualmente lavorando per l&#39;individuazione precoce di disturbi dello sviluppo, potenzialmente ancor prima che i bambini presentano caratteristiche comportamentali associati<sup&gt; Eg11</sup&gt;. Varie strategie e tecniche sono stati segnalati come un mezzo per garantire il comfort e la cooperazione dei bambini durante le sessioni di neuroimaging. Gioca terapia<sup&gt; 12</sup&gt;, Approcci comportamentali<sup&gt; 13, 14,15, 16-18</sup&gt; E simulazione<sup&gt; 19</sup&gt;, L&#39;utilizzo delle aree scanner finto<sup&gt; 20,21</sup&gt;, Il rilassamento di base<sup&gt; 22</sup&gt; E una combinazione di queste tecniche<sup&gt; 23</sup&gt; Hanno tutti dimostrato di migliorare il rispetto dei partecipanti e quindi la risonanza magnetica qualità dei dati. Ancora più importante, queste strategie hanno dimostrato di aumentare il comfort delle famiglie e dei bambini coinvolti<sup&gt; 12</sup&gt;. Uno dei principali progressi di tali tecniche per la pratica clinica è la possibilità di evitare la sedazione o anestesia generale (GA) come un modo per gestire la conformità dei bambini durante le sessioni di imaging RM<sup&gt; 19,20</sup&gt;. Nel report video corrente, vi presentiamo un protocollo pediatrico neuroimaging con linee guida e procedure che hanno dimostrato di avere successo fino ad oggi nei bambini piccoli.

Watch this Scientific Journal Video about Making MR Imaging Child's Play - Pediatric Neuroimaging Protocol, Guidelines and Procedure at JoVE.com

Making MR Imaging Child&#039;s Play - Pediatric Neuroimaging Protocol, Guidelines and Procedure

Nonostante l&#39;aumento nell&#39;uso dei strutturali e la risonanza magnetica funzionale (fMRI) negli esseri umani, lo studio delle giovani popolazioni pediatriche rimane una sfida. Vi presentiamo un hands-on, passo-passo protocollo video, tra cui linee guida per medici e ricercatori che intendono svolgere (f), risonanza magnetica nei bambini piccoli.

Fare Giocare MR Child Imaging - Protocollo Neuroimaging Pediatrica, linee guida e procedure

Within the last decade there has been an increase in the use of structural and functional magnetic resonance imaging (fMRI) to investigate the neural ...

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Making MR Imaging Child's Play - Pediatric Neuroimaging Protocol, Guidelines and Procedure

18.0K Views.  Children’s Hospital Boston. Nonostante l'aumento nell'uso dei strutturali e la risonanza magnetica funzionale (fMRI) negli esseri umani, lo studio delle giovani popolazioni pediatriche rimane una sfida. Vi presentiamo un hands-on, passo-passo protocollo video, tra cui linee guida per medici e ricercatori che intendono svolgere (f), risonanza magnetica nei bambini piccoli.