Qingbo Xu

Loss of p53 accelerates neointimal lesions of vein bypass grafts in mice.

Mechanical stress-induced DNA damage and rac-p38MAPK signal pathways mediate p53-dependent apoptosis in vascular smooth muscle cells.

Active and passive smoking, chronic infections, and the risk of carotid atherosclerosis: prospective results from the Bruneck Study.

Smooth muscle cells in transplant atherosclerotic lesions are originated from recipients, but not bone marrow progenitor cells.

Both donor and recipient origins of smooth muscle cells in vein graft atherosclerotic lesions.

Phosphorylation of threonine 154 in p40phox is an important physiological signal for activation of the neutrophil NADPH oxidase.

Plasma cardiac troponin T closely correlates with infarct size in a mouse model of acute myocardial infarction.

Role of heat shock proteins in atherosclerosis.

Mechanical stress-induced apoptosis in the cardiovascular system.

Increased risk of atherosclerosis is confined to CagA-positive Helicobacter pylori strains: prospective results from the Bruneck study.

Mechanical stretch-induced apoptosis in smooth muscle cells is mediated by beta1-integrin signaling pathways.

Cross-reactive B-cell epitopes of microbial and human heat shock protein 60/65 in atherosclerosis.

Activation of heat shock transcription factor 1 in atherosclerosis.

Infections, heat shock proteins, and atherosclerosis.

Mechanical stress-activated PKCdelta regulates smooth muscle cell migration.

Circulating progenitor cells regenerate endothelium of vein graft atherosclerosis, which is diminished in ApoE-deficient mice.

Endothelial replacement and angiogenesis in arteriosclerotic lesions of allografts are contributed by circulating progenitor cells.

Heat-shock protein 60-reactive CD4+CD28null T cells in patients with acute coronary syndromes.

Soluble RANKL and risk of nontraumatic fracture.

Autoimmunity to heat shock proteins in atherosclerosis.

Autoimmune and inflammatory mechanisms in atherosclerosis.

Thrombosis and neointima formation in vein grafts are inhibited by locally applied aspirin through endothelial protection.

Abundant progenitor cells in the adventitia contribute to atherosclerosis of vein grafts in ApoE-deficient mice.

Proteomic and metabolomic analysis of vascular smooth muscle cells: role of PKCdelta.

Mouse models of arteriosclerosis: from arterial injuries to vascular grafts.

Association of anti-heat shock protein 65 antibodies with development of postoperative atrial fibrillation.

Loss of PKC-delta alters cardiac metabolism.

Ischemic preconditioning exaggerates cardiac damage in PKC-delta null mice.

Biomechanical stress-induced signaling in smooth muscle cells: an update.

Pitfalls of proteomics.

Mouse models of vein grafts.

Vascular proteomics: linking proteomic and metabolomic changes.

Biomechanical stress induces IL-6 expression in smooth muscle cells via Ras/Rac1-p38 MAPK-NF-kappaB signaling pathways.

Association of high intracellular, but not serum, heat shock protein 70 with postoperative atrial fibrillation.

Adventitial progenitor cells contribute to arteriosclerosis.

Anti-heat shock protein 60 autoantibodies induce atherosclerosis in apolipoprotein E-deficient mice via endothelial damage.

Proteomic and metabolomic analyses of atherosclerotic vessels from apolipoprotein E-deficient mice reveal alterations in inflammation, oxidative stress, and energy metabolism.

Gene transfer of a broad spectrum CC-chemokine inhibitor reduces vein graft atherosclerosis in apolipoprotein E-knockout mice.

Progenitor cells in vascular disease.

Proteomic dataset of Sca-1+ progenitor cells.

Proteomic dataset of mouse aortic smooth muscle cells.

Role of oxidative stress in angiotensin-II mediated contraction of human conduit arteries in patients with cardiovascular disease.

Association of serum-soluble heat shock protein 60 with carotid atherosclerosis: clinical significance determined in a follow-up study.

New mouse model of vein bypass graft atherosclerosis.

Accelerated arteriosclerosis of vein grafts in inducible NO synthase(-/-) mice is related to decreased endothelial progenitor cell repair.

The impact of progenitor cells in atherosclerosis.

Involvement of the antimicrobial peptide LL-37 in human atherosclerosis.

Oxidized phospholipids predict the presence and progression of carotid and femoral atherosclerosis and symptomatic cardiovascular disease: five-year prospective results from the Bruneck study.

Oxidized low-density lipoprotein autoantibodies, chronic infections, and carotid atherosclerosis in a population-based study.

Characterisation of progenitor cells in human atherosclerotic vessels.

TLR4 expression in mouse embryonic stem cells and in stem cell-derived vascular cells is regulated by epigenetic modifications.

The molecular mechanisms of vascular restenosis: Which genes are crucial?

Genetic and acquired inflammatory conditions are synergistically associated with early carotid atherosclerosis.

Sca-1+ progenitors derived from embryonic stem cells differentiate into endothelial cells capable of vascular repair after arterial injury.

Stem cell-derived Sca-1+ progenitors differentiate into smooth muscle cells, which is mediated by collagen IV-integrin alpha1/beta1/alphav and PDGF receptor pathways.

HDAC3 is crucial in shear- and VEGF-induced stem cell differentiation toward endothelial cells.

Proteomic analysis reveals higher demand for antioxidant protection in embryonic stem cell-derived smooth muscle cells.

Endothelial progenitor cells are mobilized after cardiac surgery.

Mechanical stress-initiated signal transduction in vascular smooth muscle cells in vitro and in vivo.

Proteomics and metabolomics combined in cardiovascular research.

Oxidized phospholipids, lipoprotein(a), lipoprotein-associated phospholipase A2 activity, and 10-year cardiovascular outcomes: prospective results from the Bruneck study.

Soluble receptor activator of nuclear factor-kappa B ligand and risk for cardiovascular disease.

Lacking cytokine production in ES cells and ES-cell-derived vascular cells stimulated by TNF-alpha is rescued by HDAC inhibitor trichostatin A.

Integrated membrane protein analysis of mature and embryonic stem cell-derived smooth muscle cells using a novel combination of CyDye/biotin labeling.

Progenitor cells in vascular repair.

Endothelial progenitor cells, cardiovascular risk factors, cytokine levels and atherosclerosis--results from a large population-based study.

Association of Met439Thr substitution in heat shock protein 70 gene with postoperative atrial fibrillation and serum HSP70 protein levels.

Stem cell therapy for vascular disease.

Combined metabolomic and proteomic analysis of human atrial fibrillation.

Myocardial ischaemia-reperfusion injury in haematopoietic cell-restricted beta1 integrin knockout mice.

Vessel graft atherosclerosis in murine models.

Vascular repair by endothelial progenitor cells.

Rapid endothelial turnover in atherosclerosis-prone areas coincides with stem cell repair in apolipoprotein E-deficient mice.

Proteomic and metabolomic analysis of smooth muscle cells derived from the arterial media and adventitial progenitors of apolipoprotein E-deficient mice.

Common CCR5-del32 frameshift mutation associated with serum levels of inflammatory markers and cardiovascular disease risk in the Bruneck population.

Stem cells and transplant arteriosclerosis.

eNOS-ERalpha complex goes to telomerase.

Letter by Metzler et al regarding article, "Intracoronary KAI-9803 as an adjunct to primary coronary intervention for acute ST-segment elevation myocardial infarction".

Association of genetic variation on chromosome 9p21 with susceptibility and progression of atherosclerosis: a population-based, prospective study.

Regulatory role of thioredoxin in homocysteine-induced monocyte chemoattractant protein-1 secretion in monocytes/macrophages.

Lipoprotein-associated phospholipase A2 activity, ferritin levels, metabolic syndrome, and 10-year cardiovascular and non-cardiovascular mortality: results from the Bruneck study.

Proteomics identifies thymidine phosphorylase as a key regulator of the angiogenic potential of colony-forming units and endothelial progenitor cell cultures.

Proteomic and metabolomic analysis of cardioprotection: Interplay between protein kinase C epsilon and delta in regulating glucose metabolism of murine hearts.

Embryonic stem cell differentiation into smooth muscle cells is mediated by Nox4-produced H2O2.

Vascular remodeling in diabetes: don't leave without your STAT5.

Asymmetric and symmetric dimethylarginines are of similar predictive value for cardiovascular risk in the general population.

SDF1 gene variation is associated with circulating SDF1alpha level and endothelial progenitor cell number: the Bruneck Study.

ADAMTS-7 mediates vascular smooth muscle cell migration and neointima formation in balloon-injured rat arteries.

Splicing of HDAC7 modulates the SRF-myocardin complex during stem-cell differentiation towards smooth muscle cells.

Caspase-8, a double-edged sword for EPC functioning.

Proteomic analysis reveals presence of platelet microparticles in endothelial progenitor cell cultures.

Sustained activation of XBP1 splicing leads to endothelial apoptosis and atherosclerosis development in response to disturbed flow.

Regulatory T cells ameliorate hyperhomocysteinaemia-accelerated atherosclerosis in apoE-/- mice.

PGC-1alpha attenuates neointimal formation via inhibition of vascular smooth muscle cell migration in the injured rat carotid artery.

Single nucleotide polymorphism on chromosome 9p21 and endothelial progenitor cells in a general population cohort.

A role of matrix metalloproteinase-8 in atherosclerosis.

Vascular progenitor cells and atherosclerosis.

Homocysteine promotes vascular smooth muscle cell migration by induction of the adipokine resistin.

Immune-mediated mechanisms of endothelial damage in atherosclerosis.

Cartilage oligomeric matrix protein maintains the contractile phenotype of vascular smooth muscle cells by interacting with alpha(7)beta(1) integrin.

Histone deacetylase 3 is critical in endothelial survival and atherosclerosis development in response to disturbed flow.

Proteomics, metabolomics, and immunomics on microparticles derived from human atherosclerotic plaques.

Crucial role of nrf3 in smooth muscle cell differentiation from stem cells.

Endothelial damage and stem cell repair in atherosclerosis.

Endothelial precursors in vascular repair.

Disturbed flow-enhanced endothelial turnover in atherosclerosis.

Histone deacetylase 7 controls endothelial cell growth through modulation of beta-catenin.

Comparative proteomics profiling reveals role of smooth muscle progenitors in extracellular matrix production.

Short communication: asymmetric dimethylarginine impairs angiogenic progenitor cell function in patients with coronary artery disease through a microRNA-21-dependent mechanism.

The mechanism of stem cell differentiation into smooth muscle cells.

Different effects of angiotensin II and angiotensin-(1-7) on vascular smooth muscle cell proliferation and migration.

Progenitor cells in arteriosclerosis: good or bad guys?

Human cardiac and bone marrow stromal cells exhibit distinctive properties related to their origin.

Coronary artery disease-related genetic variant on chromosome 10q11 is associated with carotid intima-media thickness and atherosclerosis.

Resident vascular progenitor cells.

Protein kinase C{delta} deficiency accelerates neointimal lesions of mouse injured artery involving delayed reendothelialization and vasohibin-1 accumulation.

Topical HDL administration reduces vein graft atherosclerosis in apo E deficient mice.

Pluripotent stem cell differentiation into vascular cells: a novel technology with promises for vascular re(generation).

Bone marrow resident and circulating progenitor cells in patients undergoing cardiac surgery.

Proteomic characterization of human early pro-angiogenic cells.

Signalling pathways that regulate endothelial differentiation from stem cells.

Role of histone deacetylases in vascular cell homeostasis and arteriosclerosis.

Cartilage oligomeric matrix protein inhibits vascular smooth muscle calcification by interacting with bone morphogenetic protein-2.

Metabolic homeostasis is maintained in myocardial hibernation by adaptive changes in the transcriptome and proteome.

Comparative lipidomics profiling of human atherosclerotic plaques.

Extracellular matrix composition and remodeling in human abdominal aortic aneurysms: a proteomics approach.

Chromobox protein homolog 3 is essential for stem cell differentiation to smooth muscles in vitro and in embryonic arteriogenesis.

Adventitial biology: differentiation and function.

Splicing of histone deacetylase 7 modulates smooth muscle cell proliferation and neointima formation through nuclear β-catenin translocation.

Association of variation at the ABO locus with circulating levels of soluble intercellular adhesion molecule-1, soluble P-selectin, and soluble E-selectin: a meta-analysis.

Galectin-9 protein expression in endothelial cells is positively regulated by histone deacetylase 3.

Molecular chaperones and heat shock proteins in atherosclerosis.

Functional impact of heterogeneous nuclear ribonucleoprotein A2/B1 in smooth muscle differentiation from stem cells and embryonic arteriogenesis.

Nrf3-Pla2g7 Interaction Plays an Essential Role in Smooth Muscle Cell Differentiation From Stem Cells.

Pentraxin-3 as a marker of advanced atherosclerosis results from the Bruneck, ARMY and ARFY Studies.

An updated view on stem cell differentiation into smooth muscle cells.

RAGE mediates accelerated diabetic vein graft atherosclerosis induced by combined mechanical stress and AGEs via synergistic ERK activation.

Cathode ray tube (CRT) recycling: current capabilities in China and research progress.

Contribution of stem cells to neointimal formation of decellularized vessel grafts in a novel mouse model.

8,9-Epoxyeicosatrienoic acid inhibits antibody production of B lymphocytes in mice.

Increased stability of phosphatase and tensin homolog by intermedin leading to scavenger receptor A inhibition of macrophages reduces atherosclerosis in apolipoprotein E-deficient mice.

Direct reprogramming of fibroblasts into endothelial cells capable of angiogenesis and reendothelialization in tissue-engineered vessels.

Hyperhomocysteinemia exaggerates adventitial inflammation and angiotensin II-induced abdominal aortic aneurysm in mice.

Upregulation of a disintegrin and metalloproteinase with thrombospondin motifs-7 by miR-29 repression mediates vascular smooth muscle calcification.

Functional role of matrix metalloproteinase-8 in stem/progenitor cell migration and their recruitment into atherosclerotic lesions.

CTLA4-IgG ameliorates homocysteine-accelerated atherosclerosis by inhibiting T-cell overactivation in apoE(-/-) mice.

Oxidation-specific biomarkers, prospective 15-year cardiovascular and stroke outcomes, and net reclassification of cardiovascular events.

XBP1 mRNA splicing triggers an autophagic response in endothelial cells through BECLIN-1 transcriptional activation.

α1-Adrenergic receptors mediate combined signals initiated by mechanical stretch stress and norepinephrine leading to accelerated mouse vein graft atherosclerosis.

ADAMTS7 cleavage and vascular smooth muscle cell migration is affected by a coronary-artery-disease-associated variant.

Blood flow and stem cells in vascular disease.

Smooth muscle cells differentiated from reprogrammed embryonic lung fibroblasts through DKK3 signaling are potent for tissue engineering of vascular grafts.

Vascular endothelial cell growth-activated XBP1 splicing in endothelial cells is crucial for angiogenesis.

Adventitial stem cells in vein grafts display multilineage potential that contributes to neointimal formation.

MicroRNA-200C and -150 play an important role in endothelial cell differentiation and vasculogenesis by targeting transcription repressor ZEB1.

Deficiency of cartilage oligomeric matrix protein causes dilated cardiomyopathy.

Sirolimus stimulates vascular stem/progenitor cell migration and differentiation into smooth muscle cells via epidermal growth factor receptor/extracellular signal-regulated kinase/β-catenin signaling pathway.

Tetrahydrobiopterin determines vascular remodeling through enhanced endothelial cell survival and regeneration.

Histone deacetylase 3 unconventional splicing mediates endothelial-to-mesenchymal transition through transforming growth factor β2.

Matrix metalloproteinase-8 promotes vascular smooth muscle cell proliferation and neointima formation.

Endothelial lineage differentiation from induced pluripotent stem cells is regulated by microRNA-21 and transforming growth factor β2 (TGF-β2) pathways.

Over-expression of HSP47 augments mouse embryonic stem cell smooth muscle differentiation and chemotaxis.

Macrophages control vascular stem/progenitor cell plasticity through tumor necrosis factor-α-mediated nuclear factor-κB activation.

Stem cells accumulate on a decellularized arterial xenograft in vivo.

Stem/Progenitor cells in vascular regeneration.

Role of biomechanical forces in stem cell vascular lineage differentiation.

Bidirectional cross-regulation between the endothelial nitric oxide synthase and β-catenin signalling pathways.

Discrimination and net reclassification of cardiovascular risk with lipoprotein(a): prospective 15-year outcomes in the Bruneck Study.

Unspliced X-box-binding protein 1 (XBP1) protects endothelial cells from oxidative stress through interaction with histone deacetylase 3.

MicroRNA-199b modulates vascular cell fate during iPS cell differentiation by targeting the notch ligand jagged1 and enhancing VEGF signaling.

Genetic targeting of sprouting angiogenesis using Apln-CreER.

Expression of Human Tissue Factor Pathway Inhibitor on Vascular Smooth Muscle Cells Inhibits Secretion of Macrophage Migration Inhibitory Factor and Attenuates Atherosclerosis in ApoE-/- Mice.

ADAMTS-7 Inhibits Re-Endothelialization of Injured Arteries and Promotes Vascular Remodeling Via Cleavage of Thrombospondin-1.