Anton Wellstein

Distinct Response of Circulating microRNAs to the Treatment of Pancreatic Cancer Xenografts with FGFR and ALK Kinase Inhibitors.

Melanoma angiogenesis and metastasis modulated by ribozyme targeting of the secreted growth factor pleiotrophin.

Human trophoblast and choriocarcinoma expression of the growth factor pleiotrophin attributable to germ-line insertion of an endogenous retrovirus.

Structure and phylogenetic analysis of an endogenous retrovirus inserted into the human growth factor gene pleiotrophin.

Pleiotrophin signaling through anaplastic lymphoma kinase is rate-limiting for glioblastoma growth.

Immunolocalization of an FGF-binding protein reveals a widespread expression pattern during different stages of mouse embryo development.

Significance of the expression of the growth factor pleiotrophin in pancreatic cancer patients.

Anti-apoptotic signaling of pleiotrophin through its receptor, anaplastic lymphoma kinase.

Midkine binds to anaplastic lymphoma kinase (ALK) and acts as a growth factor for different cell types.

A role for TGF-beta in estrogen and retinoid mediated regulation of the nuclear receptor coactivator AIB1 in MCF-7 breast cancer cells.

Estradiol rapidly activates Akt via the ErbB2 signaling pathway.

Complex regulation of the fibroblast growth factor-binding protein in MDA- MB-468 breast cancer cells by CCAAT/enhancer-binding protein beta.

Heregulin-beta1 regulates the estrogen receptor-alpha gene expression and activity via the ErbB2/PI 3-K/Akt pathway.

Effect of estradiol on estrogen receptor-alpha gene expression and activity can be modulated by the ErbB2/PI 3-K/Akt pathway.

Up-regulation of fibroblast growth factor-binding protein, by beta-catenin during colon carcinogenesis.

Impact of the nuclear receptor coactivator AIB1 isoform AIB1-Delta3 on estrogenic ligands with different intrinsic activity.

Systemic morphine administration suppresses genes involved in antigen presentation.

Altered Rho GTPase signaling pathways in breast cancer cells.

Overexpression of the nuclear receptor coactivator AIB1 (SRC-3) during progression of pancreatic adenocarcinoma.

Differential regulation of a fibroblast growth factor-binding protein during skin carcinogenesis and wound healing.

The nuclear receptor coactivator AIB1 mediates insulin-like growth factor I-induced phenotypic changes in human breast cancer cells.

Heregulin-beta1 regulates the estrogen receptor-alpha gene expression and activity via the ErbB2/PI 3-K/Akt pathway.

Vascular leakage in chick embryos after expression of a secreted binding protein for fibroblast growth factors.

Identification of the fibroblast growth factor (FGF)-interacting domain in a secreted FGF-binding protein by phage display.

Role of fibroblast growth factor-binding protein in the pathogenesis of HIV-associated hemolytic uremic syndrome.

RNA silencing in vivo reveals role of p22phox in rat angiotensin slow pressor response.

Expression of a fibroblast growth factor-binding protein during the development of adenocarcinoma of the pancreas and colon.

Expression analysis of mRNA in formalin-fixed, paraffin-embedded archival tissues by mRNA in situ hybridization.

E6AP mediates regulated proteasomal degradation of the nuclear receptor coactivator amplified in breast cancer 1 in immortalized cells.

The angiogenic switch molecule, secreted FGF-binding protein, an indicator of early stages of pancreatic and colorectal adenocarcinoma.

Effects on neurite outgrowth and cell survival of a secreted fibroblast growth factor binding protein upregulated during spinal cord injury.

Epidermal growth factor receptor tyrosine phosphorylation and signaling controlled by a nuclear receptor coactivator, amplified in breast cancer 1.

The nuclear receptor coactivator amplified in breast cancer-1 is required for Neu (ErbB2/HER2) activation, signaling, and mammary tumorigenesis in mice.

Effect of FGF-binding protein 3 on vascular permeability.

Chronic antidepressant treatments increase basic fibroblast growth factor and fibroblast growth factor-binding protein in neurons.

Tyrosine phosphorylation of the nuclear receptor coactivator AIB1/SRC-3 is enhanced by Abl kinase and is required for its activity in cancer cells.

The role and regulation of the nuclear receptor co-activator AIB1 in breast cancer.

A distinct role for secreted fibroblast growth factor-binding proteins in development.

Tumor angiogenesis: initiation and targeting - therapeutic targeting of an FGF-binding protein, an angiogenic switch molecule, and indicator of early stages of gastrointestinal adenocarcinomas -.

Omics-based molecular target and biomarker identification.

Hunting ALK to feed targeted cancer therapy.

Role of the nuclear receptor coactivator AIB1-Delta4 splice variant in the control of gene transcription.

Proteomic analysis of pathways involved in estrogen-induced growth and apoptosis of breast cancer cells.

Tissue and serum microRNAs in the Kras(G12D) transgenic animal model and in patients with pancreatic cancer.

Superoxide modulates myogenic contractions of mouse afferent arterioles.

Impact of fibroblast growth factor-binding protein-1 expression on angiogenesis and wound healing.

p47(phox) is required for afferent arteriolar contractile responses to angiotensin II and perfusion pressure in mice.

Role of the nuclear receptor coactivator AIB1/SRC-3 in angiogenesis and wound healing.

Effects of the antioxidant drug tempol on renal oxygenation in mice with reduced renal mass.

Pleiotrophin (PTN) expression and function and in the mouse mammary gland and mammary epithelial cells.

The mitochondrial citrate transporter, CIC, is essential for mitochondrial homeostasis.

Dietary downregulation of mutant p53 levels via glucose restriction: mechanisms and implications for tumor therapy.

ALK receptor activation, ligands and therapeutic targeting in glioblastoma and in other cancers.

Transcriptional repression of AIB1 by FoxG1 leads to apoptosis in breast cancer cells.

Late failure of a split-thickness skin graft in the setting of homozygous factor V Leiden mutation: a case report and correlative animal model from the Wound Etiology and Healing (WE-HEAL) study.

Utility of a human-mouse xenograft model and in vivo near-infrared fluorescent imaging for studying wound healing.

Recurrence of early stage colon cancer predicted by expression pattern of circulating microRNAs.

Regulation of HER2 oncogene transcription by a multifunctional coactivator/corepressor complex.

SLC25A1, or CIC, is a novel transcriptional target of mutant p53 and a negative tumor prognostic marker.

Downstream of mutant KRAS, the transcription regulator YAP is essential for neoplastic progression to pancreatic ductal adenocarcinoma.

Conditionally reprogrammed normal and transformed mouse mammary epithelial cells display a progenitor-cell-like phenotype.

Expression of a Secreted Fibroblast Growth Factor Binding Protein-1 (FGFBP1) in Angioproliferative Kaposi Sarcoma.

Thromboxane prostanoid receptors enhance contractions, endothelin-1, and oxidative stress in microvessels from mice with chronic kidney disease.

Cell growth density modulates cancer cell vascular invasion via Hippo pathway activity and CXCR2 signaling.

Distinct serum metabolomics profiles associated with malignant progression in the KrasG12D mouse model of pancreatic ductal adenocarcinoma.

Circulating DNA and Micro-RNA in Patients with Pancreatic Cancer.

Cell density regulates cancer metastasis via the Hippo pathway.

Increased Pleiotrophin Concentrations in Papillary Thyroid Cancer.

Circulating microRNA profile predicts disease progression in patients receiving second-line treatment of lapatinib and capecitabine for metastatic pancreatic cancer.

Differential effects of superoxide and hydrogen peroxide on myogenic signaling, membrane potential, and contractions of mouse renal afferent arterioles.

Midkine and Pleiotrophin Concentrations in Amniotic Fluid in Healthy and Complicated Pregnancies.

Circulating biomarkers to monitor cancer progression and treatment.

Keratin-associated protein 5-5 controls cytoskeletal function and cancer cell vascular invasion.

Superoxide and hydrogen peroxide counterregulate myogenic contractions in renal afferent arterioles from a mouse model of chronic kidney disease.

Conditional cell reprogramming involves non-canonical β-catenin activation and mTOR-mediated inactivation of Akt.

The Role of Fibroblast Growth Factor-Binding Protein 1 in Skin Carcinogenesis and Inflammation.

Midkine and pleiotrophin concentrations in needle biopsies of breast and lung masses.

Circulating microRNAs in patients with hormone receptor-positive, metastatic breast cancer treated with dovitinib.

Circulating cell-free DNA mutation patterns in early and late stage colon and pancreatic cancer.

Blood Pressure Control by a Secreted FGFBP1 (Fibroblast Growth Factor-Binding Protein).

NRF2 prevents hypertension, increased ADMA, microvascular oxidative stress, and dysfunction in mice with two weeks of ANG II infusion.

The PPARγ agonist efatutazone delays invasive progression and induces differentiation of ductal carcinoma in situ.

Left Ventricular Dysfunction in Cancer Treatment: Is it Relevant?

Fenofibrate improves vascular endothelial function and contractility in diabetic mice.

High Salt Enhances Reactive Oxygen Species and Angiotensin II Contractions of Glomerular Afferent Arterioles From Mice With Reduced Renal Mass.

Fibroblast Growth Factor Binding Protein 3 (FGFBP3) impacts carbohydrate and lipid metabolism.

Reprint of: Circulating cell-free DNA mutation patterns in early and late stage colon and pancreatic cancer.

Single-Molecule Real-Time (SMRT) Full-Length RNA-Sequencing Reveals Novel and Distinct mRNA Isoforms in Human Bone Marrow Cell Subpopulations.

Short- and Long-Term Effects of CDK4/6 Inhibition on Early-Stage Breast Cancer.

Loss of ANCO1 repression at AIB1/YAP targets drives breast cancer progression.

Cadherin 11 Promotes Immunosuppression and Extracellular Matrix Deposition to Support Growth of Pancreatic Tumors and Resistance to Gemcitabine in Mice.

An AIB1 Isoform Alters Enhancer Access and Enables Progression of Early-Stage Triple-Negative Breast Cancer.