Masamitsu Iino

Phosphatidylinositol 3-kinase suppresses glucose-stimulated insulin secretion by affecting post-cytosolic [Ca(2+)] elevation signals.

Two-photon excitation imaging of pancreatic islets with various fluorescent probes.

Simultaneous imaging of Ca2+ signals in interstitial cells of Cajal and longitudinal smooth muscle cells during rhythmic activity in mouse ileum.

Genome-wide transcriptional orchestration of circadian rhythms in Drosophila.

Transient receptor potential 1 regulates capacitative Ca(2+) entry and Ca(2+) release from endoplasmic reticulum in B lymphocytes.

Functional characterization of the type 1 inositol 1,4,5-trisphosphate receptor coupling domain SII(+/-) splice variants and the Opisthotonos mutant form.

Novel mutations in C-terminal channel region of the ryanodine receptor in malignant hyperthermia patients.

Hydrophobic modifications at 1-phosphate of inositol 1,4,5-trisphosphate analogues enhance receptor binding.

The high-affinity calcium[bond]calmodulin-binding site does not play a role in the modulation of type 1 inositol 1,4,5-trisphosphate receptor function by calcium and calmodulin.

Intercellular coupling mechanism for synchronized and noise-resistant circadian oscillators.

A transcription factor response element for gene expression during circadian night.

Family affairs of intracellular Ca(2+)-release channels.

Molecular basis and physiological functions of dynamic Ca2+ signalling in smooth muscle cells.

Switch to anaerobic glucose metabolism with NADH accumulation in the beta-cell model of mitochondrial diabetes. Characteristics of betaHC9 cells deficient in mitochondrial DNA transcription.

Effects of insulin-like growth factor I on climbing fibre synapse elimination during cerebellar development.

Glucose metabolism and glutamate analog acutely alkalinize pH of insulin secretory vesicles of pancreatic beta-cells.

Intracellular delivery of glutathione S-transferase into mammalian cells.

Functional and biochemical analysis of the type 1 inositol (1,4,5)-trisphosphate receptor calcium sensor.

Spatiotemporal laser inactivation of inositol 1,4,5-trisphosphate receptors using synthetic small-molecule probes.

NFAT functions as a working memory of Ca2+ signals in decoding Ca2+ oscillation.

Isoform-specific phosphorylation of metabotropic glutamate receptor 5 by protein kinase C (PKC) blocks Ca2+ oscillation and oscillatory translocation of Ca2+-dependent PKC.

Enzymatic production of RNAi libraries from cDNAs.

[Ca2+ imaging in interstitial cells of Cajal during rhythmic activity].

Universality and flexibility in gene expression from bacteria to human.

Molecular-timetable methods for detection of body time and rhythm disorders from single-time-point genome-wide expression profiles.

Modification of intracellular Ca2+ dynamics by laser inactivation of inositol 1,4,5-trisphosphate receptor using membrane-permeant probes.

Real-time imaging of myosin II regulatory light-chain phosphorylation using a new protein biosensor.

Cross talk between metabotropic and ionotropic glutamate receptor-mediated signaling in parallel fiber-induced inositol 1,4,5-trisphosphate production in cerebellar Purkinje cells.

System-level identification of transcriptional circuits underlying mammalian circadian clocks.

Rapid Ca2+-dependent increase in oxygen consumption by mitochondria in single mammalian central neurons.

[Not Available].

BAD detects coincidence of G2/M phase and growth factor deprivation to regulate apoptosis.

NO signalling decodes frequency of neuronal activity and generates synapse-specific plasticity in mouse cerebellum.

[Analysis of intracellular membrane protein function by small molecule-based chromophore-assisted laser inactivation].

Maintenance of presynaptic function by AMPA receptor-mediated excitatory postsynaptic activity in adult brain.

Ca2+ shuttling between endoplasmic reticulum and mitochondria underlying Ca2+ oscillations.

Ca2+-dependent inositol 1,4,5-trisphosphate and nitric oxide signaling in cerebellar neurons.

Postsynaptic inositol 1,4,5-trisphosphate signaling maintains presynaptic function of parallel fiber-Purkinje cell synapses via BDNF.

Ca2+ lightning conveys cell-cell contact information inside the cells.

Coupling of STIM1 to store-operated Ca2+ entry through its constitutive and inducible movement in the endoplasmic reticulum.

[Trends in Physiology].

Regulation of cell functions by Ca2+ oscillation.

Junctophilin-mediated channel crosstalk essential for cerebellar synaptic plasticity.

Optical glutamate sensor for spatiotemporal analysis of synaptic transmission.

Induction of cerebellar long-term depression requires activation of calcineurin in Purkinje cells.

Regulation of neurite growth by spontaneous Ca2+ oscillations in astrocytes.

Abnormal features in mutant cerebellar Purkinje cells lacking junctophilins.

Postsynaptic GABAB receptor signalling enhances LTD in mouse cerebellar Purkinje cells.

Involvement of protein-tyrosine phosphatase PTPMEG in motor learning and cerebellar long-term depression.

Regulation of long-term depression and climbing fiber territory by glutamate receptor delta2 at parallel fiber synapses through its C-terminal domain in cerebellar Purkinje cells.

Identification of new functions of Ca2+ release from intracellular stores in central nervous system.

Selective photoinactivation of protein function through environment-sensitive switching of singlet oxygen generation by photosensitizer.

Functional crosstalk between cell-surface and intracellular channels mediated by junctophilins essential for neuronal functions.

Temporal switching and cell-to-cell variability in Ca2+ release activity in mammalian cells.

Spatiotemporal dynamics of Ca2+ signaling and its physiological roles.

Imaging extrasynaptic glutamate dynamics in the brain.

Imaging of Ca2+ and related signaling molecules and investigation of their functions in the brain.

Inositol 1,4,5-trisphosphate signaling maintains the activity of glutamate uptake in Bergmann glia.

Visualization of glutamate as a volume transmitter.

Nitric oxide-induced calcium release via ryanodine receptors regulates neuronal function.

β-catenin regulates parathyroid hormone/parathyroid hormone-related protein receptor signals and chondrocyte hypertrophy through binding to the intracellular C-terminal region of the receptor.

Nitric oxide-induced calcium release: activation of type 1 ryanodine receptor by endogenous nitric oxide.

Calcium-dependent N-cadherin up-regulation mediates reactive astrogliosis and neuroprotection after brain injury.

Imaging intraorganellar Ca2+ at subcellular resolution using CEPIA.

In vivo visualization of subtle, transient, and local activity of astrocytes using an ultrasensitive Ca(2+) indicator.

Divergent Activity Profiles of Type 1 Ryanodine Receptor Channels Carrying Malignant Hyperthermia and Central Core Disease Mutations in the Amino-Terminal Region.

Neuronal Regulation of Schwann Cell Mitochondrial Ca(2+) Signaling during Myelination.

Visualization of Ca2+ Filling Mechanisms upon Synaptic Inputs in the Endoplasmic Reticulum of Cerebellar Purkinje Cells.

Whisker experience-dependent mGluR signaling maintains synaptic strength in the mouse adolescent cortex.

Genetically Encoded Fluorescent Indicators for Organellar Calcium Imaging.

Nitric Oxide-induced Activation of the Type 1 Ryanodine Receptor Is Critical for Epileptic Seizure-induced Neuronal Cell Death.