Department of Pharmacology,
Graduate School of Medicine,
Department of Pharmacology, Graduate School of Medicine
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Phosphatidylinositol 3-kinase suppresses glucose-stimulated insulin secretion by affecting post-cytosolic [Ca(2+)] elevation signals.
Diabetes Jan, 2002 | Pubmed ID: 11756327
Two-photon excitation imaging of pancreatic islets with various fluorescent probes.
Diabetes Feb, 2002 | Pubmed ID: 11815453
Simultaneous imaging of Ca2+ signals in interstitial cells of Cajal and longitudinal smooth muscle cells during rhythmic activity in mouse ileum.
The Journal of physiology Feb, 2002 | Pubmed ID: 11826167
Genome-wide transcriptional orchestration of circadian rhythms in Drosophila.
The Journal of biological chemistry Apr, 2002 | Pubmed ID: 11854264
Transient receptor potential 1 regulates capacitative Ca(2+) entry and Ca(2+) release from endoplasmic reticulum in B lymphocytes.
The Journal of experimental medicine Mar, 2002 | Pubmed ID: 11901194
Functional characterization of the type 1 inositol 1,4,5-trisphosphate receptor coupling domain SII(+/-) splice variants and the Opisthotonos mutant form.
Biophysical journal Apr, 2002 | Pubmed ID: 11916857
Novel mutations in C-terminal channel region of the ryanodine receptor in malignant hyperthermia patients.
Japanese journal of pharmacology Feb, 2002 | Pubmed ID: 11928716
Hydrophobic modifications at 1-phosphate of inositol 1,4,5-trisphosphate analogues enhance receptor binding.
Bioorganic & medicinal chemistry letters Mar, 2002 | Pubmed ID: 11958992
The high-affinity calcium[bond]calmodulin-binding site does not play a role in the modulation of type 1 inositol 1,4,5-trisphosphate receptor function by calcium and calmodulin.
The Biochemical journal Aug, 2002 | Pubmed ID: 11972451
Intercellular coupling mechanism for synchronized and noise-resistant circadian oscillators.
Journal of theoretical biology Jun, 2002 | Pubmed ID: 12151263
A transcription factor response element for gene expression during circadian night.
Nature Aug, 2002 | Pubmed ID: 12152080
Family affairs of intracellular Ca(2+)-release channels.
The Journal of physiology Aug, 2002 | Pubmed ID: 12154169
Molecular basis and physiological functions of dynamic Ca2+ signalling in smooth muscle cells.
Novartis Foundation symposium , 2002 | Pubmed ID: 12164306
Switch to anaerobic glucose metabolism with NADH accumulation in the beta-cell model of mitochondrial diabetes. Characteristics of betaHC9 cells deficient in mitochondrial DNA transcription.
The Journal of biological chemistry Nov, 2002 | Pubmed ID: 12169697
Effects of insulin-like growth factor I on climbing fibre synapse elimination during cerebellar development.
The European journal of neuroscience Feb, 2003 | Pubmed ID: 12581172
Glucose metabolism and glutamate analog acutely alkalinize pH of insulin secretory vesicles of pancreatic beta-cells.
American journal of physiology. Endocrinology and metabolism Aug, 2003 | Pubmed ID: 12644449
Intracellular delivery of glutathione S-transferase into mammalian cells.
Biochemical and biophysical research communications Jun, 2003 | Pubmed ID: 12763035
Functional and biochemical analysis of the type 1 inositol (1,4,5)-trisphosphate receptor calcium sensor.
Biophysical journal Jul, 2003 | Pubmed ID: 12829484
Spatiotemporal laser inactivation of inositol 1,4,5-trisphosphate receptors using synthetic small-molecule probes.
Chemistry & biology Jun, 2003 | Pubmed ID: 12837383
NFAT functions as a working memory of Ca2+ signals in decoding Ca2+ oscillation.
The EMBO journal Aug, 2003 | Pubmed ID: 12881417
Isoform-specific phosphorylation of metabotropic glutamate receptor 5 by protein kinase C (PKC) blocks Ca2+ oscillation and oscillatory translocation of Ca2+-dependent PKC.
The Journal of biological chemistry Jan, 2004 | Pubmed ID: 14561742
Enzymatic production of RNAi libraries from cDNAs.
Nature genetics Feb, 2004 | Pubmed ID: 14704669
[Ca2+ imaging in interstitial cells of Cajal during rhythmic activity].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica Mar, 2004 | Pubmed ID: 14993727
Universality and flexibility in gene expression from bacteria to human.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2004 | Pubmed ID: 14999098
Molecular-timetable methods for detection of body time and rhythm disorders from single-time-point genome-wide expression profiles.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2004 | Pubmed ID: 15273285
Modification of intracellular Ca2+ dynamics by laser inactivation of inositol 1,4,5-trisphosphate receptor using membrane-permeant probes.
Chemistry & biology Aug, 2004 | Pubmed ID: 15324806
Real-time imaging of myosin II regulatory light-chain phosphorylation using a new protein biosensor.
The Biochemical journal Jan, 2005 | Pubmed ID: 15362955
Cross talk between metabotropic and ionotropic glutamate receptor-mediated signaling in parallel fiber-induced inositol 1,4,5-trisphosphate production in cerebellar Purkinje cells.
The Journal of neuroscience : the official journal of the Society for Neuroscience Oct, 2004 | Pubmed ID: 15509738
System-level identification of transcriptional circuits underlying mammalian circadian clocks.
Nature genetics Feb, 2005 | Pubmed ID: 15665827
Rapid Ca2+-dependent increase in oxygen consumption by mitochondria in single mammalian central neurons.
Cell calcium Apr, 2005 | Pubmed ID: 15755497
[Not Available].
Clinical calcium Apr, 2003 | Pubmed ID: 15775120
BAD detects coincidence of G2/M phase and growth factor deprivation to regulate apoptosis.
The Journal of biological chemistry Jul, 2005 | Pubmed ID: 15901741
NO signalling decodes frequency of neuronal activity and generates synapse-specific plasticity in mouse cerebellum.
The Journal of physiology Aug, 2005 | Pubmed ID: 15919714
[Analysis of intracellular membrane protein function by small molecule-based chromophore-assisted laser inactivation].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme Aug, 2005 | Pubmed ID: 16104611
Maintenance of presynaptic function by AMPA receptor-mediated excitatory postsynaptic activity in adult brain.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2005 | Pubmed ID: 16357208
Ca2+ shuttling between endoplasmic reticulum and mitochondria underlying Ca2+ oscillations.
EMBO reports Apr, 2006 | Pubmed ID: 16415789
Ca2+-dependent inositol 1,4,5-trisphosphate and nitric oxide signaling in cerebellar neurons.
Journal of pharmacological sciences , 2006 | Pubmed ID: 16682789
Postsynaptic inositol 1,4,5-trisphosphate signaling maintains presynaptic function of parallel fiber-Purkinje cell synapses via BDNF.
Proceedings of the National Academy of Sciences of the United States of America May, 2006 | Pubmed ID: 16709674
Ca2+ lightning conveys cell-cell contact information inside the cells.
EMBO reports Nov, 2006 | Pubmed ID: 17039254
Coupling of STIM1 to store-operated Ca2+ entry through its constitutive and inducible movement in the endoplasmic reticulum.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2006 | Pubmed ID: 17075073
[Trends in Physiology].
Nihon seirigaku zasshi. Journal of the Physiological Society of Japan , 2006 | Pubmed ID: 17175877
Regulation of cell functions by Ca2+ oscillation.
Advances in experimental medicine and biology , 2007 | Pubmed ID: 17278375
Junctophilin-mediated channel crosstalk essential for cerebellar synaptic plasticity.
The EMBO journal Apr, 2007 | Pubmed ID: 17347645
Optical glutamate sensor for spatiotemporal analysis of synaptic transmission.
The European journal of neuroscience Apr, 2007 | Pubmed ID: 17445223
Induction of cerebellar long-term depression requires activation of calcineurin in Purkinje cells.
Neuropharmacology Jun, 2007 | Pubmed ID: 17485101
Regulation of neurite growth by spontaneous Ca2+ oscillations in astrocytes.
The Journal of neuroscience : the official journal of the Society for Neuroscience Aug, 2007 | Pubmed ID: 17699677
Abnormal features in mutant cerebellar Purkinje cells lacking junctophilins.
Biochemical and biophysical research communications Nov, 2007 | Pubmed ID: 17904530
Postsynaptic GABAB receptor signalling enhances LTD in mouse cerebellar Purkinje cells.
The Journal of physiology Dec, 2007 | Pubmed ID: 17947316
Involvement of protein-tyrosine phosphatase PTPMEG in motor learning and cerebellar long-term depression.
The European journal of neuroscience Oct, 2007 | Pubmed ID: 17953619
Regulation of long-term depression and climbing fiber territory by glutamate receptor delta2 at parallel fiber synapses through its C-terminal domain in cerebellar Purkinje cells.
The Journal of neuroscience : the official journal of the Society for Neuroscience Oct, 2007 | Pubmed ID: 17978051
Identification of new functions of Ca2+ release from intracellular stores in central nervous system.
Biochemical and biophysical research communications Apr, 2008 | Pubmed ID: 18053793
Selective photoinactivation of protein function through environment-sensitive switching of singlet oxygen generation by photosensitizer.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2008 | Pubmed ID: 18172220
Functional crosstalk between cell-surface and intracellular channels mediated by junctophilins essential for neuronal functions.
Cerebellum (London, England) , 2008 | Pubmed ID: 18607668
Temporal switching and cell-to-cell variability in Ca2+ release activity in mammalian cells.
Molecular systems biology , 2009 | Pubmed ID: 19293827
Spatiotemporal dynamics of Ca2+ signaling and its physiological roles.
Proceedings of the Japan Academy. Series B, Physical and biological sciences , 2010 | Pubmed ID: 20228624
Imaging extrasynaptic glutamate dynamics in the brain.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2010 | Pubmed ID: 20308566
Imaging of Ca2+ and related signaling molecules and investigation of their functions in the brain.
Antioxidants & redox signaling Apr, 2011 | Pubmed ID: 20615120
Inositol 1,4,5-trisphosphate signaling maintains the activity of glutamate uptake in Bergmann glia.
The European journal of neuroscience Nov, 2010 | Pubmed ID: 20958799
Visualization of glutamate as a volume transmitter.
The Journal of physiology Feb, 2011 | Pubmed ID: 21115644
Nitric oxide-induced calcium release via ryanodine receptors regulates neuronal function.
The EMBO journal Jan, 2012 | Pubmed ID: 22036948
β-catenin regulates parathyroid hormone/parathyroid hormone-related protein receptor signals and chondrocyte hypertrophy through binding to the intracellular C-terminal region of the receptor.
Arthritis and rheumatism Feb, 2013 | Pubmed ID: 23124878
Nitric oxide-induced calcium release: activation of type 1 ryanodine receptor by endogenous nitric oxide.
Channels (Austin, Tex.) Jan, 2013 | Pubmed ID: 23247505
Calcium-dependent N-cadherin up-regulation mediates reactive astrogliosis and neuroprotection after brain injury.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2013 | Pubmed ID: 23798419
Imaging intraorganellar Ca2+ at subcellular resolution using CEPIA.
Nature communications , 2014 | Pubmed ID: 24923787
In vivo visualization of subtle, transient, and local activity of astrocytes using an ultrasensitive Ca(2+) indicator.
Cell reports Jul, 2014 | Pubmed ID: 24981861
Divergent Activity Profiles of Type 1 Ryanodine Receptor Channels Carrying Malignant Hyperthermia and Central Core Disease Mutations in the Amino-Terminal Region.
PloS one , 2015 | Pubmed ID: 26115329
Neuronal Regulation of Schwann Cell Mitochondrial Ca(2+) Signaling during Myelination.
Cell reports Sep, 2015 | Pubmed ID: 26365190
Visualization of Ca2+ Filling Mechanisms upon Synaptic Inputs in the Endoplasmic Reticulum of Cerebellar Purkinje Cells.
The Journal of neuroscience : the official journal of the Society for Neuroscience Dec, 2015 | Pubmed ID: 26631466
Whisker experience-dependent mGluR signaling maintains synaptic strength in the mouse adolescent cortex.
The European journal of neuroscience Aug, 2016 | Pubmed ID: 27225340
Genetically Encoded Fluorescent Indicators for Organellar Calcium Imaging.
Biophysical journal Jul, 2016 | Pubmed ID: 27477268
Nitric Oxide-induced Activation of the Type 1 Ryanodine Receptor Is Critical for Epileptic Seizure-induced Neuronal Cell Death.
EBioMedicine Aug, 2016 | Pubmed ID: 27544065
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