Stefan Raunser

High-yield expression, reconstitution and structure of the recombinant, fully functional glutamate transporter GLT-1 from Rattus norvegicus.

Oligomeric structure of the carnitine transporter CaiT from Escherichia coli.

A virulence locus of Pseudomonas aeruginosa encodes a protein secretion apparatus.

Assembly of the major light-harvesting chlorophyll-a/b complex: Thermodynamics and kinetics of neoxanthin binding.

Heterologously expressed GLT-1 associates in approximately 200-nm protein-lipid islands.

Structure and function of prokaryotic glutamate transporters from Escherichia coli and Pyrococcus horikoshii.

The architecture of the multisubunit TRAPP I complex suggests a model for vesicle tethering.

Structure of GlnK1 with bound effectors indicates regulatory mechanism for ammonia uptake.

Death domain assembly mechanism revealed by crystal structure of the oligomeric PIDDosome core complex.

Structural insight into pre-B cell receptor function.

Revival of electron crystallography.

Rubisco in complex with Rubisco large subunit methyltransferase.

STIM1 clusters and activates CRAC channels via direct binding of a cytosolic domain to Orai1.

Oligomeric structure and functional characterization of the urea transporter from Actinobacillus pleuropneumoniae.

Electron crystallography as a technique to study the structure on membrane proteins in a lipidic environment.

The Fas-FADD death domain complex structure reveals the basis of DISC assembly and disease mutations.

Structural characterization of polyglutamine fibrils by solid-state NMR spectroscopy.

Real-space processing of helical filaments in SPARX.

Molecular architecture of the multisubunit homotypic fusion and vacuole protein sorting (HOPS) tethering complex.

Functional characterization of the human α-cardiac actin mutations Y166C and M305L involved in hypertrophic cardiomyopathy.

Membrane fusion intermediates via directional and full assembly of the SNARE complex.

Structure of the rigor actin-tropomyosin-myosin complex.

Ras GTPase activating (RasGAP) activity of the dual specificity GAP protein Rasal requires colocalization and C2 domain binding to lipid membranes.

FHOD1 is a combined actin filament capping and bundling factor that selectively associates with actin arcs and stress fibers.

A syringe-like injection mechanism in Photorhabdus luminescens toxins.

Molecular architecture of the human protein deacetylase Sirt1 and its regulation by AROS and resveratrol.

Gestalt-binding of tropomyosin on actin during thin filament activation.

Role of centrosomal adaptor proteins of the TACC family in the regulation of microtubule dynamics during mitotic cell division.

A facile method for preparation of tailored scaffolds for DNA-origami.

Functional characterization of human myosin-18A and its interaction with F-actin and GOLPH3.

The centrosomal adaptor TACC3 and the microtubule polymerase chTOG interact via defined C-terminal subdomains in an Aurora-A kinase-independent manner.

The role of Cdc42 and Gic1 in the regulation of septin filament formation and dissociation.

Modular assembly of RWD domains on the Mis12 complex underlies outer kinetochore organization.

Mechanism of Tc toxin action revealed in molecular detail.

Prebiotic cell membranes that survive extreme environmental pressure conditions.

The pseudo GTPase CENP-M drives human kinetochore assembly.

Structural identification of the Vps18 β-propeller reveals a critical role in the HOPS complex stability and function.

Architecture and conformational switch mechanism of the ryanodine receptor.

Structure of the F-actin-tropomyosin complex.

Structure of mega-hemocyanin reveals protein origami in snails.

Exploring the stability limits of actin and its suprastructures.

The Habc domain of the SNARE Vam3 interacts with the HOPS tethering complex to facilitate vacuole fusion.

pH-regulated selectivity in supramolecular polymerizations: switching between Co- and homopolymers.

Deciphering the tubulin code.

Functional homologies in vesicle tethering.

Condensation agents determine the temperature-pressure stability of F-actin bundles.

The role of Bni5 in the regulation of septin higher-order structure formation.

Determinants of amyloid fibril degradation by the PDZ protease HTRA1.

An interbacterial NAD(P)(+) glycohydrolase toxin requires elongation factor Tu for delivery to target cells.

Insights from the reconstitution of the divergent outer kinetochore of Drosophila melanogaster.

Molecular requirements for the inter-subunit interaction and kinetochore recruitment of SKAP and Astrin.

Cryo-EM structure of a human cytoplasmic actomyosin complex at near-atomic resolution.

Membrane insertion of a Tc toxin in near-atomic detail.

Haptoglobin.

Multivalent Rab interactions determine tether-mediated membrane fusion.

Electron Cryo-microscopy as a Tool for Structure-Based Drug Development.

The mother of all actins?

Architecture and mechanism of the late endosomal Rab7-like Ypt7 guanine nucleotide exchange factor complex Mon1-Ccz1.

Retromer-driven membrane tubulation separates endosomal recycling from Rab7/Ypt7-dependent fusion.

Structure of the RZZ complex and molecular basis of its interaction with Spindly.